9th International Conference on Neonatal and Childhood Pulmonary Vascular Disease
erated from 4D RV-Function 2, as this method measures TAPSE differently than the traditional M-mode measurement of TAPSE.
San Francisco, March 10–12, 2016
Bronchopulmonary dysplasia–associated pulmonary hypertension (BPD-PH) is a prominent source of morbidity and mortality in the premature infant population. Both hypoxia and hyperoxia have been implicated as potential contributors to the pathogenesis of BPD-PH. The optimal oxygen saturation target range to minimize risk for BPD-PH is in dispute. A large, single-center neonatal intensive care unit has changed its pulse oximetry targets twice in the past 7 years for reasons unrelated to PH risk. We hypothesized that exposure to increased pulse oximetry targets would result in lower rates of BPD-PH. We retrospectively compared rates of PH and use of PH medications (sildenafil, inhaled nitric oxide [iNO], and bosentan) in at-risk infants exposed to varying saturation targets. Infants with birth weight of