A CASE OF IDIOPATHIC TETANUS TREATED WITH SUBCUTANEOUS INJECTION
OF ESERINE SULPHAS?RECOVERY. By Sorabji Furdoonji Gazdhar, l.m. Medical Officer, Nausari Hospital. M. R., a Hindoo of the labouring class, found himself one morning on awaking that he was unable to open his mouth completely and his whole body stiff. Ascribing this to the effects of cold from sleeping in the open air he went to his work as usual; but he soon began to experience shocks passing through the body which rendered work impossible, and he returned to his house. The stiffness of the body increased and Graduthe spasms came at shorter intervals. ally the jaws became locked up completely, and The he could take nourishment with difficulty. ordinary run of medicines proving ineffectual, I tried hypodermic injections of eserine sulphas in grain doses. The effect was marvellous; for after two or three injections the tonic spasmodic condition of the body became less marked, the intervals between the clonic spasms increased, and the stiffness of the jaws lessened considerably. Within a week from the commencement of the injections the spasms had completely disappeared and the mouth could be opened to its full extent. About a dozen injections were performed in all, and the patient made a
complete
recovery. Remarks.?I have given this case in order that a more extended trial may be giveu to the drug by the profession. The disease runs so very fatal a course and the fatal termination is sometimes so rapid that any remedy which might prove efficacious may with advantage be brought to the notice of the profession.
OF ESERINE SULPHAS?RECOVERY. By Sorabji Furdoonji Gazdhar, l.m. Medical Officer, Nausari Hospital. M. R., a Hindoo of the labouring class, found himself one morning on awaking that he was unable to open his mouth completely and his whole body stiff. Ascribing this to the effects of cold from sleeping in the open air he went to his work as usual; but he soon began to experience shocks passing through the body which rendered work impossible, and he returned to his house. The stiffness of the body increased and Graduthe spasms came at shorter intervals. ally the jaws became locked up completely, and The he could take nourishment with difficulty. ordinary run of medicines proving ineffectual, I tried hypodermic injections of eserine sulphas in grain doses. The effect was marvellous; for after two or three injections the tonic spasmodic condition of the body became less marked, the intervals between the clonic spasms increased, and the stiffness of the jaws lessened considerably. Within a week from the commencement of the injections the spasms had completely disappeared and the mouth could be opened to its full extent. About a dozen injections were performed in all, and the patient made a
complete
recovery. Remarks.?I have given this case in order that a more extended trial may be giveu to the drug by the profession. The disease runs so very fatal a course and the fatal termination is sometimes so rapid that any remedy which might prove efficacious may with advantage be brought to the notice of the profession.
