Suppl.completo reimpag._4b_. 04/10/13 15:55 Pagina 44
Case Report
A rare case of oral anthracosis resembling an oral leukoplakia C. Tiberio, M. Venturi, D. Servidio, F. Diano, D.B. Gissi Department of Biomedical and Neuromotor Sciences, Section of Oral Sciences, University of Bologna, Italy Anthracosis is a non pathologic condition characterized by deposit of carbon particles in the lungs and in the lymph nodes. It is caused by excessive exposure to carbonaceous material including tobacco smoke. Anthracosis is given by deposits of carbon particles phagocytized by macrophages that subsequently move to perivascular connective tissue and lymph nodes. Extrapulmonary anthracosis is very rare, and its etiology is not well established. We report a case of anthracotic pigment deposit in the cheek mucosa of a 56 years old strong smoker woman. The patient presented with a white diffuse oral lesion in the cheek mucosa. The presence of any traumatic factor was excluded and the patients underwent an incisional biopsy. The histological examination showed hyperkeratosis of the epithelium and carbon-laden macrophages located in the superficial chorion. The diagnosis of oral anthracosis associated with tobacco related keratosis was established basing on the histological findings and personal history of tabagism. The patient was convinced to stop smoking. After some time the white diffused lesions disappeared confirming the previously established diagnosis of tobacco related keratosis associated with anthracosis. The pathogenesis of extrapulmonary anthracosis is still unclear. A few case reports described anthracosis of the esophagus 1 but, to the best of our knowledge, there are no reports in the literature describing this condition in the oral cavity. The presence of white plaques diffused to all oral cavity requires differentiation from oral leukoplakia which is a lesion at risk of malignant transformation and that requires a radical surgical approach. Instead, the diagnosis of oral anthracosis in a smoker patient only imposes to convince the patient to stop smoking. References 1.
44
Murata T, Imai T, Hoshino K, Kato M, Tanigawa K, Higuchi T, Kozuka Y, Inoue R, Watanabe M, Shiraishi T, Takubo K. Esophageal anthracosis: lesion mimicking malignant melanoma. Pathol Int 2002 Jul; 52(7):488-91.
Annali di Stomatologia 2013; Suppl. 2: 1-48
Case Report
A rare case of oral anthracosis resembling an oral leukoplakia C. Tiberio, M. Venturi, D. Servidio, F. Diano, D.B. Gissi Department of Biomedical and Neuromotor Sciences, Section of Oral Sciences, University of Bologna, Italy Anthracosis is a non pathologic condition characterized by deposit of carbon particles in the lungs and in the lymph nodes. It is caused by excessive exposure to carbonaceous material including tobacco smoke. Anthracosis is given by deposits of carbon particles phagocytized by macrophages that subsequently move to perivascular connective tissue and lymph nodes. Extrapulmonary anthracosis is very rare, and its etiology is not well established. We report a case of anthracotic pigment deposit in the cheek mucosa of a 56 years old strong smoker woman. The patient presented with a white diffuse oral lesion in the cheek mucosa. The presence of any traumatic factor was excluded and the patients underwent an incisional biopsy. The histological examination showed hyperkeratosis of the epithelium and carbon-laden macrophages located in the superficial chorion. The diagnosis of oral anthracosis associated with tobacco related keratosis was established basing on the histological findings and personal history of tabagism. The patient was convinced to stop smoking. After some time the white diffused lesions disappeared confirming the previously established diagnosis of tobacco related keratosis associated with anthracosis. The pathogenesis of extrapulmonary anthracosis is still unclear. A few case reports described anthracosis of the esophagus 1 but, to the best of our knowledge, there are no reports in the literature describing this condition in the oral cavity. The presence of white plaques diffused to all oral cavity requires differentiation from oral leukoplakia which is a lesion at risk of malignant transformation and that requires a radical surgical approach. Instead, the diagnosis of oral anthracosis in a smoker patient only imposes to convince the patient to stop smoking. References 1.
44
Murata T, Imai T, Hoshino K, Kato M, Tanigawa K, Higuchi T, Kozuka Y, Inoue R, Watanabe M, Shiraishi T, Takubo K. Esophageal anthracosis: lesion mimicking malignant melanoma. Pathol Int 2002 Jul; 52(7):488-91.
Annali di Stomatologia 2013; Suppl. 2: 1-48
