Accepted Article
Received Date : 14-Feb-2014 Revised Date : 14-May-2014 Accepted Date : 17-May-2014 Article type : Systematic Review
090-2014.R1 Systematic Review
A systematic review of enhanced recovery care after colorectal surgery in elderly patients
(2)
Authors, qualifications and main appointments:
Nigel M Bagnall1 – BMedSc MBChB MSc MRCS, Clinical Research Fellow George Malietzis1,2 – MBBS MSc MRCS, Clinical Research Fellow Robin H Kennedy1,2 – MBBS MS FRCS, Adjunct Professor of Surgery Thanos Athanasiou1 – MD PhD FETCS FRCS, Professor of Surgery Omar Faiz1,2 – BSc MBBS MS FRCS, Honorary Senior Lecturer Ara Darzi1 – MD FMedSci FRCS, Professor of Surgery 1. Department of Surgery and Cancer, Imperial College London, St Mary’s Hospital, Paddington, London, W2 1NY, United Kingdom 2. St Marks Hospital and Academic Institute, Northwick Park NHS Trust, Watford Road, Harrow, Middlesex, HA1 3UJ, United Kingdom
(3)
Corresponding Author:
Nigel Bagnall, Department of Surgery & Cancer, Imperial College London, Room 1029, QEQM, St Mary’s Hospital, London, United Kingdom, W2 1NY. This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process which may lead to differences between this version and the Version of Record. Please cite this article as an 'Accepted Article', doi: 10.1111/codi.12718 This article is protected by copyright. All rights reserved.
Accepted Article
E-mail: [email protected] Tel: +44 (0)203 3127619 Fax: +44 (0)203 3126309 (5)
Contribution of each author:
All authors substantially contributed to the development the study, including the systematic review strategy and design methodology, contributed in the analysis and presentation of results, drafting and critically revising the manuscript for submission. All authors have reviewed the final version and agree to be accountable for the integrity of the work. In addition, specifically Nigel Bagnall and George Malietzis were the two independent reviewers of selected articles for the systematic review and extracted data for analysis, Omar Faiz acted as third reviewer to resolve disagreements. Thanos Athanasiou also appraised and reviewed the extracted data. Robin Kennedy and Ara Darzi provided additional expert knowledge and experience on enhanced recovery in originating and revising the manuscript. (6)
Word count for text excluding abstract and references: 3,339.
Abstract Aim: Enhanced recovery after surgery (ERAS) can decrease complications and reduces hospital stay. Less certain is whether elderly patients can fully adhere to and benefit from ERAS. We aimed to determine the safety, feasibility and efficacy of enhanced recovery after colorectal surgery in patients aged ≥65 years old. Method: A systematic search of Medline, EMBASE and Cochrane (was performed to identify: (1) studies comparing elderly patients managed with ERAS versus traditional care, (2) cohort studies of ERAS with results of elderly versus younger patients, and (3) any case series of ERAS in elderly patients. End points of interest were length of hospital stay, complications, mortality, readmission and re-operation, and ERAS protocol adherence. Results: Sixteen studies were included. Two randomised controlled trials demonstrated shorter hospital stay in elderly patients with ERAS compared to elderly patients with non-
This article is protected by copyright. All rights reserved.
Accepted Article
ERAS (9 vs 13.2 days; P
Received Date : 14-Feb-2014 Revised Date : 14-May-2014 Accepted Date : 17-May-2014 Article type : Systematic Review
090-2014.R1 Systematic Review
A systematic review of enhanced recovery care after colorectal surgery in elderly patients
(2)
Authors, qualifications and main appointments:
Nigel M Bagnall1 – BMedSc MBChB MSc MRCS, Clinical Research Fellow George Malietzis1,2 – MBBS MSc MRCS, Clinical Research Fellow Robin H Kennedy1,2 – MBBS MS FRCS, Adjunct Professor of Surgery Thanos Athanasiou1 – MD PhD FETCS FRCS, Professor of Surgery Omar Faiz1,2 – BSc MBBS MS FRCS, Honorary Senior Lecturer Ara Darzi1 – MD FMedSci FRCS, Professor of Surgery 1. Department of Surgery and Cancer, Imperial College London, St Mary’s Hospital, Paddington, London, W2 1NY, United Kingdom 2. St Marks Hospital and Academic Institute, Northwick Park NHS Trust, Watford Road, Harrow, Middlesex, HA1 3UJ, United Kingdom
(3)
Corresponding Author:
Nigel Bagnall, Department of Surgery & Cancer, Imperial College London, Room 1029, QEQM, St Mary’s Hospital, London, United Kingdom, W2 1NY. This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process which may lead to differences between this version and the Version of Record. Please cite this article as an 'Accepted Article', doi: 10.1111/codi.12718 This article is protected by copyright. All rights reserved.
Accepted Article
E-mail: [email protected] Tel: +44 (0)203 3127619 Fax: +44 (0)203 3126309 (5)
Contribution of each author:
All authors substantially contributed to the development the study, including the systematic review strategy and design methodology, contributed in the analysis and presentation of results, drafting and critically revising the manuscript for submission. All authors have reviewed the final version and agree to be accountable for the integrity of the work. In addition, specifically Nigel Bagnall and George Malietzis were the two independent reviewers of selected articles for the systematic review and extracted data for analysis, Omar Faiz acted as third reviewer to resolve disagreements. Thanos Athanasiou also appraised and reviewed the extracted data. Robin Kennedy and Ara Darzi provided additional expert knowledge and experience on enhanced recovery in originating and revising the manuscript. (6)
Word count for text excluding abstract and references: 3,339.
Abstract Aim: Enhanced recovery after surgery (ERAS) can decrease complications and reduces hospital stay. Less certain is whether elderly patients can fully adhere to and benefit from ERAS. We aimed to determine the safety, feasibility and efficacy of enhanced recovery after colorectal surgery in patients aged ≥65 years old. Method: A systematic search of Medline, EMBASE and Cochrane (was performed to identify: (1) studies comparing elderly patients managed with ERAS versus traditional care, (2) cohort studies of ERAS with results of elderly versus younger patients, and (3) any case series of ERAS in elderly patients. End points of interest were length of hospital stay, complications, mortality, readmission and re-operation, and ERAS protocol adherence. Results: Sixteen studies were included. Two randomised controlled trials demonstrated shorter hospital stay in elderly patients with ERAS compared to elderly patients with non-
This article is protected by copyright. All rights reserved.
Accepted Article
ERAS (9 vs 13.2 days; P
