Oral Abstracts Antiretroviral Therapy and its Complications O1 The Protease Inhibitor Versus Ongoing Triple-therapy (PIVOT) trial N Paton, W Stohr, A Arenas-Pinto, D Dunn and for the PIVOT Trial Group MRC Clinical Trials Unit at UCL, London, UK Background: Previous randomised trials show patients switching to PI monotherapy maintain high rates of viral load (VL) suppression over 4896 weeks, sometimes meeting VL non-inferiority criteria. However, longerterm resistance and toxicity risks are uncertain and the place of PI monotherapy in long-term management therefore remains controversial. Methods: PIVOT was a pragmatic 5-year prospective, randomised, controlled, open-label strategy trial in HIV-positive adults taking a stable NNRTI or PIbased regimen who had no previous VL failure and had VL

Abstracts of the Third Joint Conference of the British HIV Association (BHIVA) with the British Association for Sexual Health and HIV (BASHH), 1-4 April 2014, Liverpool, UK.

Abstracts of the Third Joint Conference of the British HIV Association (BHIVA) with the British Association for Sexual Health and HIV (BASHH), 1-4 April 2014, Liverpool, UK. - PDF Download Free
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