RESEARCH ARTICLE
Acceptance of Combined Coronary CT Angiography and Myocardial CT Perfusion versus Conventional Coronary Angiography in Patients with Coronary Stents— Intraindividual Comparison Matthias Rief1☯, Sarah Feger1☯, Peter Martus2, Michael Laule3, Marc Dewey1‡*, Eva Schönenberger4‡ 1 Department of Radiology, Charité, Medical School, Berlin, Germany, 2 Institute for Clinical Epidemiology and Applied Biostatistics, Eberhard Karls University Tübingen, Germany, 3 Department of Cardiology, Charité, Medical School, Berlin, Germany, 4 Department of Medicine, Medical School Hannover, Hannover, Germany
OPEN ACCESS Citation: Rief M, Feger S, Martus P, Laule M, Dewey M, Schönenberger E (2015) Acceptance of Combined Coronary CT Angiography and Myocardial CT Perfusion versus Conventional Coronary Angiography in Patients with Coronary Stents— Intraindividual Comparison. PLoS ONE 10(9): e0136737. doi:10.1371/journal.pone.0136737 Editor: Carmine Pizzi, University of Bologna, ITALY Received: January 5, 2015 Accepted: August 3, 2015 Published: September 1, 2015 Copyright: © 2015 Rief et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Data Availability Statement: All relevant data are within the paper and its Supporting Information files. Funding: The CARS-320 study was supported by a grant from BRACCO. The authors of this manuscript declare relationships with the following companies: Prof. Dewey has received grant support from the Heisenberg Program of the DFG for a professorship (DE 1361/14-1), the FP7 Program of the European Commission for the randomized multicenter DISCHARGE trial (603266-2, HEALTH-2012.2.4.-2), the European Regional Development Fund (20072013 2/05, 20072013 2/48), the German Heart
☯ These authors contributed equally to this work. ‡ These authors are joint senior authors on this work. * [email protected]
Abstract Objectives To evaluate how well patients with coronary stents accept combined coronary computed tomography angiography (CTA) and myocardial CT perfusion (CTP) compared with conventional coronary angiography (CCA).
Background While combined CTA and CTP may improve diagnostic accuracy compared with CTA alone, patient acceptance of CTA/CTP remains to be defined.
Methods A total of 90 patients with coronary stents prospectively underwent CTA/CTP (both with contrast agent, CTP with adenosine) and CCA as part of the CARS-320 study. In this group, an intraindividual comparison of patient acceptance of CTA, CTP, and CCA was performed.
Results CTP was experienced to be significantly more painful than CTA (p
Acceptance of Combined Coronary CT Angiography and Myocardial CT Perfusion versus Conventional Coronary Angiography in Patients with Coronary Stents— Intraindividual Comparison Matthias Rief1☯, Sarah Feger1☯, Peter Martus2, Michael Laule3, Marc Dewey1‡*, Eva Schönenberger4‡ 1 Department of Radiology, Charité, Medical School, Berlin, Germany, 2 Institute for Clinical Epidemiology and Applied Biostatistics, Eberhard Karls University Tübingen, Germany, 3 Department of Cardiology, Charité, Medical School, Berlin, Germany, 4 Department of Medicine, Medical School Hannover, Hannover, Germany
OPEN ACCESS Citation: Rief M, Feger S, Martus P, Laule M, Dewey M, Schönenberger E (2015) Acceptance of Combined Coronary CT Angiography and Myocardial CT Perfusion versus Conventional Coronary Angiography in Patients with Coronary Stents— Intraindividual Comparison. PLoS ONE 10(9): e0136737. doi:10.1371/journal.pone.0136737 Editor: Carmine Pizzi, University of Bologna, ITALY Received: January 5, 2015 Accepted: August 3, 2015 Published: September 1, 2015 Copyright: © 2015 Rief et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Data Availability Statement: All relevant data are within the paper and its Supporting Information files. Funding: The CARS-320 study was supported by a grant from BRACCO. The authors of this manuscript declare relationships with the following companies: Prof. Dewey has received grant support from the Heisenberg Program of the DFG for a professorship (DE 1361/14-1), the FP7 Program of the European Commission for the randomized multicenter DISCHARGE trial (603266-2, HEALTH-2012.2.4.-2), the European Regional Development Fund (20072013 2/05, 20072013 2/48), the German Heart
☯ These authors contributed equally to this work. ‡ These authors are joint senior authors on this work. * [email protected]
Abstract Objectives To evaluate how well patients with coronary stents accept combined coronary computed tomography angiography (CTA) and myocardial CT perfusion (CTP) compared with conventional coronary angiography (CCA).
Background While combined CTA and CTP may improve diagnostic accuracy compared with CTA alone, patient acceptance of CTA/CTP remains to be defined.
Methods A total of 90 patients with coronary stents prospectively underwent CTA/CTP (both with contrast agent, CTP with adenosine) and CCA as part of the CARS-320 study. In this group, an intraindividual comparison of patient acceptance of CTA, CTP, and CCA was performed.
Results CTP was experienced to be significantly more painful than CTA (p
