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J Adolesc Health. Author manuscript; available in PMC 2017 July 01. Published in final edited form as: J Adolesc Health. 2016 July ; 59(1): 30–37. doi:10.1016/j.jadohealth.2016.03.004.
Exposure to Violence and Virologic and Immunological Outcomes Among Youth with Perinatal HIV Deborah Kacanek, Sc.D.a, Kathleen Malee, Ph.D.b, Claude A. Mellins, Ph.D.c, Katherine Tassiopoulos, D.Sc., M.P.H.d, Renee Smith, Ph.D.e, Mitzie Grant, Ph.D.f, Sonia Lee, Ph.D.g, Danish Q. Siddiqui, M.P.H.h, and Ana Puga, M.D., M.P.H.i for the Pediatric HIV/AIDS Cohort Study
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aDepartment
of Biostatistics, Center for Biostatistics in AIDS Research, Harvard TH Chan School of Public Health, Boston, MA
bDepartment
of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago IL cHIV
Center for Clinical and Behavioral Studies, Department of Psychiatry, Columbia University Medical Center, NY, NY
dDepartment
of Epidemiology, Harvard TH Chan School of Public Health, Boston, MA
eDepartment
of Pediatrics, University of Illinois at Chicago, Chicago, IL
fDepartment
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of Psychiatry, Drexel University College of Medicine & St. Christopher's Hospital for Children, Philadelphia, PA gEunice
Kennedy Shriver National Institute of Child Health and Human Development, Bethesda,
MD hDepartment iChildren's
of Pediatrics Infectious Diseases, Tulane School of Medicine, New Orleans, LA
Diagnostic and Treatment Center, Fort Lauderdale, FL
Abstract
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Purpose—Exposure to violence in childhood has been linked to adverse health outcomes. Little is known about the prevalence and relationship of youth and caregiver violence exposure to clinical outcomes among youth with perinatal HIV infection (PHIV). We evaluated associations of youth and caregiver violence exposure with unsuppressed viral load (VL) (HIV RNA>400 copies/ml) and CD4%400 copies/ml, and b) CD4 percentage