J Food Sci Technol DOI 10.1007/s13197-011-0568-9
ORIGINAL ARTICLE
Ameliorating activity of ginger (Zingiber officinale) extract against lead induced renal toxicity in male rats Y. Amarnath Reddy & M. Chalamaiah & B. Ramesh & G. Balaji & P. Indira
Revised: 8 September 2011 / Accepted: 10 October 2011 # Association of Food Scientists & Technologists (India) 2011
Abstract Lead poisoning has been known to be associated with structural and functional abnormalities of multiple organ systems of human body. The aim of this investigation was to study the renal protective effects of ginger (Zingiber officinale) extract in lead induced toxicity rats. In this study renal glutathione (GSH) level, glutathione peroxidase (GPX), glutathione-s-transferase (GST), and catalase enzymes were measured in lead nitrate (300 mg/kg BW), and lead nitrate plus ginger extract (150 mg/kg BW) treated rat groups for 1 week and 3 weeks respectively. The glutathione level and GSH dependent antioxidant enzymes such as glutathione peroxidase, glutathione-stransferase, and catalase significantly (P
ORIGINAL ARTICLE
Ameliorating activity of ginger (Zingiber officinale) extract against lead induced renal toxicity in male rats Y. Amarnath Reddy & M. Chalamaiah & B. Ramesh & G. Balaji & P. Indira
Revised: 8 September 2011 / Accepted: 10 October 2011 # Association of Food Scientists & Technologists (India) 2011
Abstract Lead poisoning has been known to be associated with structural and functional abnormalities of multiple organ systems of human body. The aim of this investigation was to study the renal protective effects of ginger (Zingiber officinale) extract in lead induced toxicity rats. In this study renal glutathione (GSH) level, glutathione peroxidase (GPX), glutathione-s-transferase (GST), and catalase enzymes were measured in lead nitrate (300 mg/kg BW), and lead nitrate plus ginger extract (150 mg/kg BW) treated rat groups for 1 week and 3 weeks respectively. The glutathione level and GSH dependent antioxidant enzymes such as glutathione peroxidase, glutathione-stransferase, and catalase significantly (P
