LETTER TO Anastomotic Leak Increases Distant Recurrence and Long-term Mortality After Curative Resection for Colonic Cancer To the Editor: e commend the detailed and insightful analysis of the impact of colonic anastomotic leaks on survival by Krarup and coworkers who utilized the Danish colorectal cancer database.1 Their principal finding is that anastomotic leak is associated with enhanced distant disease recurrence. In their subgroup analysis of stage 3 cancer resections, however, we note with interest that distant recurrence and overall mortality rates were not significantly impacted by anastomotic leaks if there was prompt administration of adjuvant chemotherapy (

Anastomotic Leak Increases Distant Recurrence and Long-term Mortality After Curative Resection for Colonic Cancer.

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