RESEARCH ARTICLE
Antenatal Corticosteroids for Reducing Adverse Maternal and Child Outcomes in Special Populations of Women at Risk of Imminent Preterm Birth: A Systematic Review and Meta-Analysis Rachel M. Amiya1,2, Linda B. Mlunde3, Erika Ota1*, Toshiyuki Swa4, Olufemi T. Oladapo5☯, Rintaro Mori1☯
OPEN ACCESS
1 Department of Health Policy, National Center for Child Health and Development, Tokyo, Japan, 2 Department of Family Nursing, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan, 3 Department of Community and Global Health, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan, 4 Graduate School of Human Sciences, Osaka University, Suita, Japan, 5 UNDP/UNFPA/ UNICEF/WHO/World Bank Special Programme of Research, Development and Research Training in Human Reproduction (HRP), Department of Reproductive Health and Research, World Health Organization, Geneva, Switzerland
Citation: Amiya RM, Mlunde LB, Ota E, Swa T, Oladapo OT, Mori R (2016) Antenatal Corticosteroids for Reducing Adverse Maternal and Child Outcomes in Special Populations of Women at Risk of Imminent Preterm Birth: A Systematic Review and MetaAnalysis. PLoS ONE 11(2): e0147604. doi:10.1371/ journal.pone.0147604
☯ These authors contributed equally to this work. *
[email protected] Editor: Craig Rubens, Seattle Childrens Hospital, UNITED STATES
Background
Received: March 27, 2015 Accepted: January 6, 2016 Published: February 3, 2016 Copyright: © 2016 Amiya et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Data Availability Statement: All relevant data are within the paper and its Supporting Information files. Funding: This study was funded by the UNDP/ UNFPA/UNICEF/WHO/World Bank Special Programme of Research, Development and Research Training in Human Reproduction (HRP), Department of Reproductive Health and Research, World Health Organization. The manuscript represents the views of the named authors only. The grant of National Center for Child Health and Development 26A-5 (http://www.ncchd.go.jp/center/
Abstract
This study synthesizes available evidence on antenatal corticosteroids (ACS) use among special subgroups of women at risk of imminent preterm birth, including those (1) with pregestational and gestational diabetes mellitus, (2) undergoing elective caesarean section (CS) in late preterm (34 to