ANTITOXIN IN

Iii connection with this tant paper has been

Medical Journal by describing a successful

TETANUS.

subject

published

a very imporin the BritislL

Major Seinple, R.A.M.C.,

of intracerebral injection of antitoxin in tetanus. This is the first case of the kind that has, as far as I know, occurred in English practice, though some twenty case

have been treated in the same manner in France and with good results. Dr. Semple enters fully into the rationale of the

proceeding

and

gives

introduction of the why antidote into the substance of the brain succeeds when subcutaneous and intravenous injections

reasons

the direct

there is in the

same number of the Journal (Jan. 7th) an account of a case treated by subcutaneous injection in the Middlesex Hospital, in which the procedure adopted failed

fail.

Curiously

THE INDIAN MEDICAL GAZETTE.

130

to relieve

symptoms

or

avert death.

The

case

appears to have been of a very violent description, and the treatment was not commenced until the

symptoms

of the disease

ed and the toxin had cerebral cells.

were

very pronouncreached the

presumably

[April

1899.