American Journal of Medical G e n e t i c s 35:470-474 (1990)
Arthur Robinson-An
Appreciation
John M. Opitz Department of Medical Genetics, Shodair Hospital, Helena, Montana the Denver report. Arthur Robinson’s pioneering work on the prevalence of gonosomal aneuploidy at birth, the carrier detection of galactosemia, the natural history of (prospectively ascertained) children with sex chromosome abnormalities, amniocyte culture, and prenatal diagnosis stands as a classic accomplishment in the field. However, Art deserves equal recognition for his leadership in the teaching of clinical genetics and genetic counseling, the establishment of cytogenetics laboratories and genetics clinics which set earliest local and regional standards of highest quality, for graduate and postgraduate teaching of clinical genetics and cytogenetics, and for his role in chairing the Department of Biophysics and Genetics a t the University of Colorado, all of which have made Art the Dean of Rocky Mountain Cytogenetics and Clinical Genetics. Rare is the person as able to embody the best aspects of clinical and basic human biology while growing in personal and professional stature. Modesty prevented Arthur from mentioning the several important awards he has received for his long and distinguished career in pediatrics and genetics at the University of Colorado and the National Jewish Center for Immunology and Respiratory Medicine in Denver. These include the Gerald J . Hencman Memorial Award of the National Foundation-March of Dimes and the Virginia Apgar Memorial Award of the Metro Denver March of Dimes, the Centennial Award for DistinWhen Arthur Robinson entered Columbia University guished Service to the University of Colorado School of to study classics at the age of 16 he “sufferedfrom imma- Medicine, the Arthur B. Lorber Distinguished Service turity and a poor self-image.” At the age of 75, Dr. Award from the Council of National Trustees and Board Robinson has been ennobled by a serenity and dignity of Directors of the National Jewish HospitaUNational granted to few and experienced as a benediction by all Asthma Center in Recognition of Extraordinary who meet him. In the 28 years I have known Art, as he is Achievement to Advance Medical Service, and the Boncalled affectionately, I have always considered myself fils-Stanton Foundation Award for Significant and privileged by every contact with him, and have been Unique Contributions in the Field of Science and Mediguided and inspired by Art’s standards in clinical and cine. In 1980 and 1985 Arthur received Medical Student pediatric genetics and in applied basic sciences. Art was Awards for Excellence in Teaching and on May 21,1986, the f i r s h r one of the first-to discover the chromo- he was asked to present a Distinguished Faculty Semisome aberration in the Ullrich-Turner syndrome. His nar at the University of Colorado. In part, the 1945 need t o protect the confidentiality of the first patient he citation by HQ of the 78th Infantry Division of the U S . studied was responsible for the delay in publication of Army for Award of Bronze Star Medal and of Air Medal with Oak Leaf Cluster reads: “His leadership and outstanding devotion to duty are in accordance with the Received for publication December 27, 1988; revision received highest military traditions.” September 22, 1989. Clinical genetics, pediatric genetics and cytogenetics, Address reprint requests to: John M. Opitz, M.D., Shodair Hospiand the University of Colorado have been greatly ental, Department of Medical Genetics, P.O. Box 5539, 840 Helena riched by the work of Arthur Robinson. In the American Avenue, Helena, MT 59604.
0 1990 Wiley-Liss, Inc.
Arthur Robinson-An Appreciation
West we are proud of Arthur as the Dean in our field and grateful to have been able to benefit from his advice and consultation for over 30 years. Dr. Robinson’s bibliography is appended in the happy knowledge that this continues to be a mowing list.
PUBLICATIONS: Arthur Robinson, M.D. 1. Bullowa JGM, Alterman J , Katana N, Scannell M, Robinson A (1942): Pertussis immunitv with toxin and antitoxin. J Am Med ASSOC120:886-890. 2. Robinson A, Howard J E (1948):Atresia ofthe tricuspid valve with transoosition of the meat vessels. Am J Dls Child 75575-581. 3. Howird J E , Robinson A (1948): Acute osteomyelitis of the superior maxilla in infants. J Mt Sinai Hasp 15:101-104. 4. Laff HI, Hurst A, Robinson A (1951): Importance of bronchial involvement in primary tuberculosis of childhood. J Am Med Assac 146:778-783. 5. Public Health Service Cooperative Investigation (1953): Chemotherapy of miliary tubercuiosis and tubercaous meningitis. Pediatrics 12:38-55. 6. Robinson A, and Ro YH (1 954): Tuberculous meningitis in infants and children. Am J Dis Child 87:139-155. 7. Meyer M, Middlebrook G, Robinson A (1955): The treatment of primary tuberculosis in infancy. J Pediatr 46:398-402. 8. Meyer M, Robinson A, Middlebrook G, Alway R (1955): Possible immediate deleterious effect of isoniazid on course of tuberculous meningitis. Am Rev Tuberc 71:765. 9. Robinson A, Meyer M, Middlebrook G (1955):Tuberculin hypersensitivity in tuberculous infants treated with isoniazid. N Engl J Med 252:983-985. 10. Robinson A, Meyer M (1956): The effect of specific therapy in primary tuberculosis of the child. J Pediatr 48:705-709 11. U.S. Public Health Service Tuberculosis Prophylaxis Trial (1957): Prophylactic effects of isoniazid on primary tuberculosis in children. Am Rev Tuberc 76:942-963. 12. Robinson A (1957):Pulmonary tuberculosis: The primary lesion. Pematr Clin North Am 255-270. 13. Lanier VS, Russell WF, Heaton A, Robinson A (1958):Concentrations of active isoniazid in serum and cerebrospinal fluid of patients with tuberculosis treated with isoniazid. Pediatrics 21:910-915. 14. Puck TT, Cieciura SJ, Robinson A (1958): Genetics of somatic mammalian cells. 111.Long-term cultivation of euploid cells from human and animal subjects. J Exp Med 108:945-956. 15 Qio JH, Puck TT, Robinson A (1959): Chromosomes of human subjects with genetic defects. Anim Cell Inf Serv Newslett No. 1. 16. Puck TT, Robinson A, Tjio J H (1959): The chromosomal constitution of human subjects with genetic diseases. 11. Treacher-Collins Syndrome (mandibulo-facial dysostosis). Anim Cell Inf Serv Newslett l(2). 17. Puck TT, Robinson A, Tjio J H (1959):The genetic defect in testicular feminization. Anim Cell Inf Serv Newslett l(3). 18. Tjio JH, Puck TT, Robinson A (1959):The somatic chromosomal constitution of some human subjects with genetic defects. Proc Natl Acad Sci USA 45:1008-1016. 19. Committee of the Section on Diseases of the Chest, American Academy of Pediatrics (1959): Primary bacterial resistance in tuberculosis. Pediatrics 24:493-494. 20. Robinson A (1959): Simplified fixation and staining for delineation of nuclear chromatin by the Barr technique. Pedatrics 24:858-859. 21. Puck TT, Robinson A (1960): Additional chromosomal satellites in man. Anim Cell Inf Serv Newslett 2(3). 22. Puck TT, Robinson A, Tjio J H (1960):Familial primary amenorrhea due to testicular feminization: A human gene affecting sex differentiation. Proc Sac Exp Biol Med 103:192-196. 23. Tjio J H , Puck TT, Robinson A (1960):The human chromosomal satellites in normal persons and in two patients with Marfan’s syndrome. Proc Natl Acad Sci USA 46:532-539. 24. Robinson A (1960): How much is too much? Am J Dis Child 100:1-2. 25. Robinson A, et al. (14 signatories) (1960-1961): A proposed standard system of nomenclature of human mitotic chromosomes. JAMA 174:159-162. Am J Hum Genet 12:384-388. Cerebral Palsy Bull (Suppl), 2(3):1-9. J Hered 51(5):214-221. Pediatrics 27:485-488.
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26. Robinson A (1961): The human chromosomes. Am J Dis Child 101:379-398. 27. Robinson A (19621: The diagnosis of galactosemia and galactosemia carriers. Anim Cell Inf Serv Newslett 3:7. 28. Robinson A (1962): The culture of peripheral leukocytes for chromosomal analysis using small amounts of blood. Anim Cell Inf Serv Newslett 3:8. 29. Robinson A (1962): Genetics. The New Physician, Special Issue, p. 237. 30. Robinson A, et al. 11963):Participant: The London Conference on the Normal Human Karyotype CIBA Foundation; Guest Symposium, International Study Group on Human Chromosomes, London, August 28-30, 1963. Cytogenetics 2:264-268. 31. Robinson A (1963): The assay of galactokinase and galactose-lphosphate uridyl transferase activity in human erythrocytes: A presumed test for heterozygous carriers of the galactosemic defect. J Exp Med 118:359-370. 32. Robinson A, Puck TT (1964): Nuclear chromatin studies in newborn infants. Anim Cell Inf Serv Newslett 5:4-5. 33. Robinson A, Puck TT (1964): Procedure for sex chromatin determination in newborns by means of buccal smears. Anim Cell Inf Serv Newslett 5:1 -2. 34. Robinson A, Puck TT (1964):A procedure for sex chromatin determination in newborns by means ofamnion biopsies. Anim Cell Inf Serv Newslett 53. 35. Robinson A, Priest RE, Bigler PC (1964): Male pseudohermaphrodite with X Y K O mosaicism and bilateral gonadoblastomas. Lancet 1:111-112. 36. Robinson A, Puck TT (1965): Sex chromatin in newborns: Presumptive evidence for external factors in human nondisjunction. Science 148:83-85. 37. Robinson A (1965j: Book review: Human Chromosome Methodology, edited by Jorge Yunis. Science 150:1704. 38. Randall DL, Reiquam CW, Githens JH, Robinson A (1965): Familial myeloproliferative disease: A new syndrome closely simulating myelogenous leukemia in childhood. Am J Dis Child 110:479-500. 39. Robinson A (1966): Clinical genetics. In Taylor ES (ed): “Beck‘s Obstetrical Practice, Eighth Edition.” Baltimore: Williams & Wilkins, ch 49, pp 621-640. 40. Robinson A, Puck TT (1966): Infectious hepatitis and Down’s syndrome. Lancet 1:313. 41. Robinson A (1966):Genetic counseling. S Dakota J Med 19:27-29 42. Robinson A (1966): Participant and Signatory: Standardization in Human Cytogenetics. National Foundation-March of Dimes, Chicago Conference, 2C2). 43. Robinson A, Puck TT (1967):Studies on chromosomal nondisjunction in man. 11. Am J Hum Genet 19:112-129. 44. Priest JH, Robinson A (1967): Dermatoglyphics in Down’s syndrome and congenital rubella. Lancet 1:683. 45. Snyder RD, Robinson A (1967): Leucine-induced hypoglycemia. Am J Dis Child 113566-570. 46. Puck TT,Robinson A (1967): Some perspectives in human cytogenetics. In Keller W (ed): “Biologic Basis of Pediatric Practice.” ch 144, pp 1407-1421. 47. Robinson A, Puck ‘IT (1967): Medicine and the human chromosomes. In Zubin J, Jervis GA (eds): “Psychopathology of Mental Development.” New York Grune and Stratton, pp 1-14. 48. Robinson A (1967):Book review: Chromosome Studies on Adults, by W.M. Court Brown, K.E. Buckton, P.A. Jacobs, I.M. Tough, E.B. Kuenssberg and J.D.E. Knox. Q Rev Biol42539. 49. Fulginiti VA, Kempe CH, Hathaway WE, Pearlman DS, Sieber OF, Eller JJ, Joyner JW, Sr., Robinson A (1968): Progressive vaccinia in immunologically-deficient individuals. Birth Defects 4(1):128-150. 50. Stewart J, Go S, Ellis E, Robinson A (1968): IgA and partial deletions of chromosome 18. Lancet 2:779. 51. Ott J E , Robinson A, Peakman DC (1968): DID balanced translocations. Lancet 2:1352. 52. Ott J E , Robinson A (1969): Cerebral gigantism. Am J Dis Child 117:357-368. 53. Githens JH, Muschenheim F, Fulginiti VA, Robinson A, Kay HEM (1969): Thymic alymphoplasia with XXlXY lymphoid chimerism secondary to probable maternal-fetal transfusion. J Pediatr 75:87-94. 54. Cherington M, Ott JE, Robinson A (1969): Cornelia de Lange syndrome in an adult male. Neurology 19:879-884. 55. Chemke J, Robinson A (1969): The third fontanelle. J Pediatr 75:617-622. 56. Robinson A, Goad WB, Puck TT, Harris J (1969): Studies on chromosomal nondisjunction in man. 111. Am J Hum Genet 21:466-485.
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57. Robinson A (1969): Sex differences in development. Dev Med Child Neural 11:245-246. 58. Snyder R, Robinson A (1969): Recessive sex-linked mental retardation in the absence of other recognizable abnormalities. Report of a family. Clin Pediatr 8:669-674. 59. Robinson A (1969):Medicine and the human chromosomes. Proc. Dimensions of Nutrition, Ft. Collins, Colo., July 7-11. 60. Robinson A (1969): Introductory comments on carbon 14 methods. In Hsia DY-Y ied): “Galactosemia.” Springfield: Charles C. Thomas, pp 94-97. 61. Robinson A (1969):Introduction: The Etiology and Epidemiology of Meningomyelocele and Anencephaly. Roc. Natl. Fndn. Spina Bifida Symposium, Denver, Colo., nov. 24-26. 62. Robinson A (1970): Genetic and chromosomal disorders. In Kempe CH, Silver HK, O’Brien D (eds): “Current Pediatric Diagnosis and Treatment.” Los Altos, Calif.: Lange Medical Publications, ch 32, pp 698-719. 63. Stewart Jhl, Go S, Ellis E, Robinson A (1970): Absent IgA and deletions of chromosome 18. J Med Genet 7:ll-19. 64. Priest JH, Peakman DC, Patil S, Robinson A (1970):Significance of chromosome 17ps + in three generations of a family. J Med Genet 7:142-147.65. Chemke J, Carmichael R, Stewart JM, Geer RH, Robinson A (1970): Familial XY gonadal dysgenesis. J Med Genet 7:105-111. 66. Claman HN, Merrill DA, Peakman D, Robinson A (1970):Isolated severe gamma A deficiency: Immunoglobulin levels, clinical disorders, and chromosome studies. J Lab Clin Med 75:307-315. 67. Kohn G, Robinson A (1970): Tetraploidy in cells cultured from amniotic fluid. Lancet 2:778-779. 68. Chemke J, Robinson A (1970): The third fontanelle. El Medico 20:36-37. 69. Chemke J , Robinson A (1971): The inheritance of a structural anomaly of one chromosome no. 16 in a kindred (46,16- ,C + 1. J Med Genet 8:346-350. 70. Eller E, Frankenburg W, Puck M, Robinson A (19711:Prognosis in newborn infants with X-chromosomal abnormalities. Pediatrics 47:681-688. 71. Nakashima I. Robinson A (1971): Fertility in a 45,X female. Pediatrics 47:770-773. 72. Harris JS, Robinson A (1971):X-chromosome abnormalities and the obstetrician. The value of routine nuclear sexing of newborns. Am J Obstet Gynecol 109574-583. 73. Humbert JR, Hathaway WE, Robinson A, Githens J H , Peakman DC (1971):Re-leukemia in children with a missing bone marrow C chromosome and a myeloproliferativedisorder. Br J Haematol 21:705-716. 74. Greensher A, Gersh R, Peakman D, Robinson A (1971):Fluorescence of the Y and Barr body in human interphase cells. Lancet I
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75. Greensher A, Gersh R, Peakman D, Robinson A (1971): Screening of newborn infants for abnormalities of the Y chromosome. J Pediatr 79:305-306. 76. Greensher A, Gersh R, Peakman D, Robinson A (1971): Intrauterine diagnosis of fetal sex. Pediatrics 48:159. 77. RobinsonA (1971): Book review: Genetic Disorders ofMan. edited by R.M. Goodman. Science 172:463. 78. Robinson A (1971): Clinical genetics. In Taylor ES (ed): “Becks Obstetrical Practice,” Ninth Edition. Baltimore: Williams and Wilkins, ch 49, pp 626-646. 79. Robinson A (1971): Genetics and society. Utah Law Rev 1971(4):487-492. 80. Robinson A, Puck M, Droegemueller W, Goodman S (1972):Intrauterine diagnosis of birth defects. In Klingberg MA, Abramovici A, Chemke J (eds): “Drugs and Fetal Development.” Advances in Experimental Medicine and Biology, Val. 27. Xew York Plenum Press, pp 419-425. 81, Greensher A, Gersh R, Peakman D, Fbbinson A (1972): Screening for abnormalities of the Y chromosome. J Pediatr 80:158. 82. Robinson A (1972): Genetic and chromosomal disorders. In Kempe CH, Silver HK, O’Brien D (eds):“Current Pediatric Diagnosis and Treatment,” Second Edition. Los Altos, Calif.: Lange Medical Publications, ch 34, pp 846-868. 83. Robinson A, Bowes W, Droegemueller W, Puck M, Goodman S, Shikes R, Greensher, A (1973):Intrauterine diagnosis: Potential complications. Am J Obstet Gynecol 116:937-941. 84. Robinson A (1973): Chromosomal disorders. In StfYe.HK, Kempe CH, Bruyn HB (eds): “Handbook of Pediatrics, Tenth Edition. Los Altos, Calif.: Lange Medical Publications, pp 652-654. 85. Robinson A (1973): Intrauterine diagnosis and ultrasound. Lancet 2:1504. 86. Robinson A, OBrien D (1974): Genetic and chromosomal disorders, including inborn errors of metabolism. In Kempe CH, Silver
HK, OBrien D (eds): “Current Pediatric Diagnosis and Treatment,” Third Edition. Los Altos, Calif.: Lange Medical Publications, ch 33, pp 859-899. 87. Reynolds B, Puck M, Robinson A (1974): Genetic counseling: An aaaraisal. Clin Genet 5:177-187. 88. %binson A (1974): Book review: Genetics of Sex Differentiation, by Ursula Mittwoch. Am Sci 62(3):362. 89. Robinson A, Puck M, Tennes K (1974): The 47,XXY karyotype. - - _ Lancet 1:1343. 90. Robinson A (1974):Neonatal deaths and sex chromosome anomalies. Lancet 1:1223. 91. Riccardi VM, Robinson A (1974): Regional genetic counseling. Rocky Mtn Med J 71:686-688. 92. Puck M, Tennes K, Frankenburg W, Bryant K, Robinson A (1975): Early childhood development of four boys with 47,XXY karyotype. Clin Genet 7:8-21. 93. Riccardi V, Robinson A 11975): Preventive medicine through genetic counseling: A regional program. Prev Med 4:126-134. 94. RobinsonA (1975):Sex chromatin in newborns. Am J Hum Genet 27:118. 95. Tennes K, Puck M, Bryant K, hankenburg W, Robinson A (1975): A developmental study of girls with trisomy X. Am J Hum Genet 27:71-80. 96. Robinson J, Tennes K, Robinson A (1975): Amniocentesis: Its impact on mothers and infants. A one-year follow-up study. Clin Genet 8:97-106. 97. Hecht F, McCaw BK, Peakman D, Robinson A (1975): Non-randam occurrence of 7-14 translocations in human lymphocyte cultures. Nature 255:243-244. 98. Peakman DC, Moreton MF, Robinson A (1975): Chromosomal mosaicism in diagnostic amniotic fluid cell cultures. Pediatr Res 9516. 99. Karsh RB, Knapp RF, Nora JJ, Wolfe RR, Robinson A (1975): Congenital heart disease in 49,XXXXY syndrome. Pediatrics 56:462-464. 100. Hays T, Humbert JR, Peakman DC, Hutter JJ, Morse HG, Robinson A, August CS (1975): Missing Y chromosome in juvenile chronic myelogenous leukemia. Humangenetik 29:259-264. 101. Goad WB, Robinson A, Puckl”(1976): Incidence ofaneuploidy in a human population. Am J Hum Genet 28:62-68. 102. Peakman DC, Robinson A (1976): Indications for chromosome analysis: Effect of new bandingtechniques. J Pediatr 88:166-167. 103. Robinson A (1976): Clinical genetics. In Taylor ES (ed): “Beck’s Obstetrical Practice and Fetal Medicine,” Tenth Edition. Baltimore: Williams and Wilkins, ch 47, pp 605-627. 104. Robinson A (1976): Genetic counseling. In Fenoglio CM, Goodman R, King DW (eds): “Developmental Genetics,” Advances in Pathology, No. 3. New York: Stratton Intercontinental Medical Book Corp., pp 95-101. 105. Robinson A, Goodman SI, O’Brien D (1976): Genetic and chromosomal disorders, including inborn errors of metabolism. In Kempe CH, Silver HK, O’Brien D (eds):“Current Pediatric Diagnosis and Treatment,” 4th Edition. Los Altos, Calif.: Lange Medical Publications, ch 33, pp 885-926. 106. Verma RS, Peakman DC, Robinson A, Lubs HA (1976): Comparison of G, Q, and R banding in 28 cases of chromosomal abnormalities. Cytogenet Cell Genet 16:479-486. 107. Henry G, Wexler P, Robinson A (1976):Rh-immune globulin after amniocentesis for genetic diagnosis. Obstet Gynecol48:557-559. 108. Peakman DC, Moreton MF, Robinson A (197’7): Prenatal diagnosis: Techniques used to aid in ruling out maternal cell contamination. J Med Genet 14:37-39. 109. Robinson A, Peakman DC (1977):Chromosome abnormalities. In Rudolph AM (ed): “Pediatrics,” 16th Edition. New York Appleton-Century-Crofts, pp 279-291. 110. Henry GP, Robinson A (1977): Equivocal amniotic fluid alphafetoprotein levels in prenatal diagnosis of neural tube defects. Am J Obstet Gynecol 127:204. 111. Tennes K, Puck M, Orfanakis D, Robinson A (1977): The early childhood development of 17 boys with sex chromosome anomalies. A prospective study. Pediatrics 59:574-583. 112. Robinson A (1977): Studies on infants and children with sex chromosomal abnormalities. In Borek C, Fenoglio CM, King DW (eds): “Cancer Biology. IV. Differentiation and Carcinogenesis.” Advances in Pathobiology, No. 6. New York: Stratton Intercontinental Medical Book Corp., pp 214-226. 113. Verma RS, Peakman DC, Robinson A, Lubs HA (1977): Two cases of Down syndrome with unusual de novo translocation. Clin Genet 11227-234. 114. Morse HG, Humbert JR, Hutter J J , Robinson A (1977): Karyotyping of bone-marrow cells in hematologic diseases. Hum Genet 37:33-39.
Arthur Robinson-An Appreciation 115. Ziter FA, Wiser WC, Robinson A (1977): Three-generation pedigree of a mobius syndrome variant with chromosome translocation. Arch Neurol 34:437-442. 116. Robinson A (1977): Book review: Population Cytogenetics: Studies in Humans, edited by E.B. Hook and I.H. Porter. Am J Hum Genet 29:548-549. 117. Robinson A (1977): Education of community physicians and paramedical genetics personnel (postgraduate training). In Lubs HA, de la Cruz F (eds): “Genetic Counseling.” New York: Raven Press, pp 369-375. 118. Rohinson A, Puck TT (1977): Trisomy clusters. Lancet 2:981-982. 119. Robinson A, Goad WB, Puck TT (1978): Some epidemiologic aspects of chromosomal aneuploidy. In Cohen BH, Lilienfeld AM, Huang PC (eds):“Genetic Issues in Public Health and Medicine.” Springfield: Charles C. Thomas, pp 206-214. 120. Robinson A, Goodman SI, O’Brien D (1978): Genetic and chromosomal disorders, including inborn errors in metabolism. In Kempe CH, Silver HK, O’Brien D (eds):“Current Pediatric Diagnosis and Treatment,” 5th Edition. Los Altos, Calif.: Lange Medical Publications, ch 33, pp 931-972. 121. Henry GP, Robinson A (1978): Prenatal genetic diagnosis. Clin Obstet Gynecol 21(2):329-340. 122. Morse HG, Ducore JM, Hays T, Peakman D, Robinson A (1978): Multiple leukemic clones in acute leukemia of childhood. Hum Genet 40:269-278. 123. Humbert JR. Morse HG. Hutter JJ, Rose B, Robinson A (1978): Non-leukemic dividing cells in the blood of leukemic patients. Am J Hematol4:217-224. 124. Henry GP, Peakman DC, Robinson A (1978): Prenatal genetic diagnosis: Nine years’ experience. Obstet Gynecol Surv 33569-577. 125. Ward BE, Cook RH, Robinson A, Austin J H (1979): Increased aneuploidy in Alzheimer disease. Am J Med Genet 3:137-144. 126. Hays T, Morse H, Peakman D, Rose B, Robinson A (1979): Cytogenetic studies of chronic myelocytic leukemia in children and adolescents. Cancer 44:2 10- 2 14. 127. Morse H, Hays T, Peakman D, Rose B, Robinson A (1979): Acute nonlymphohlasticleukemiain childhood High incidence of clonal abnormalities and non-random changes. Cancer 44:164-170. 128. Robinson A, Puck M, Pennington B, Borelli J, Hudson M (1979): Abnormalities of the sex chromosomes: A prospective study on randomly identified newborns. In Robinson A, Lubs HA, Bergsma D (eds): “Sex Chromosome Aneuploidy: Prospective Studies on Children.” New York: Alan R. Liss, Inc., for the National Foundation-March of Dimes, BD:OAS 15(1):203-241. 129. Rohinson A, Lubs HA, BergsmaD (eds) (1979): “Sex Chromosome Aneuploidy: Prospective Studies on Children.”New York Alan R. Liss, Inc., for the National Foundation-March of Dimes. BD:OAS 15(1). 130. Peakman DC, Moreton MF, Corn BJ, Robinson A (1979):Chromosomal mosaicism in amniotic fluid cell cultures. Am J Hum Genet 31:149-155. 131. Findley L, Kurnick J E , Peakman DC, Robinson A (1979): Chromosome deletion 46.XX.de1(20Koll) in anogenic mveloid metaplasia. Hum Genet 47:207-212. 132. Morse H, Hays T, Rose B, Robinson A (1979): Chromosome 1 abnormalities in relapse and terminal stages in childhood leukemia. Med Pediatr Oncol 7:9-16. 133. Hecht F, Kaiser-McCaw B: Peakman D, Robinson A (1979): New translocations in human lymphocytes: A mutagen monitoring system. Environ Health Perspect 31:19-22. 134. Pennington B, Puck M, Robinson A (1980): Language and cognitive development in 47,XXX females followed since birth. Behav. Genet 10:31-41. 135. Robinson A, Goodman SI, OBrien D (1980): Genetic and chromosomal disorders including inborn errors of metabolism. In Kempe CH, Silver HK, O’Brien D (eds):“Current Pediatric Diagnosis and Treatment,” 6th Edition. Los Altos, Calif.: Lange Medical Puhlications, ch 33, pp 947-987. 136. Ward BE. Henrv GP. Robinson A (1980): Cvtogenetic studies in 100 couples with recurrent spontaneous aiorgons. Am J Hum Genet 32549-554. 137. Robinson A et al. (1980):Participant. The XYY controversy: Researching violence and genetics. Hastings Cent Rep [Spec Supplj. 138. Ward BE, Bradley CM, Cooper JB, Rohinson A (1981): Homodicentric chromosomes: A distinctive type of dicentric chromosome. J Med Genet 18:54-58. 139. Strain J E , Smith ACM, Ward BE, Robinson A (1981): Inverted tandem duplication of the middle segment of the long arm of chromosome 14. Pediatrics 67:273-276. 140. Hecht F Peakman DC, Kaiser-McCaw B, Robinson A (1981):
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Amniocyte clones for prenatal cytogenetics. Am J Med Genet 10:51-54. 141. Salbenblatt JA, Bender BG, Puck MH, Robinson A, Webber ML (1981):Development ofeight pubertal males with 47,XXY karyotype. Clin Genet 20:141-146. 142. Sujansky E, Smith ACM, Peakman DC, McConnell TS, Baca P, Robinson A (1981): Familial pericentric inversion of chromosome 8. Am J Med Genet 10:229-235. 143. Hays T, Morse HG, Robinson A (1981):9;22;15 complex translocation in Ph’ chromosome positive CML revealed by Giemsa-11 procedure in apparent lymphoid cells of blastic crisis. Cancer Genet Cytogenet 4:283-292. 144. Robinson A, Goodman SI, O’Brien D (1982): Genetic and chromosomal disorders, including inborn errors of metabolism. In Kempe CH, Silver HK, O’Brien D (eds):“Current Pediatric Diagnosis and Treatment,” 7th Edition. Los Altos, Calif.: Lange Medical Publications, ch 33, pp 934-972. 145. Webber ML, Puck MH, Maresh MM, Goad WB, Robinson A (1982): Skeletal maturation of children with sex chromosome abnormalities. Pediatr Res 16:343-346. 146. PenninPton BF. Bender B. Puck M. Salbenblatt J. Robinson A (1982):“Learning disabilities in chiidren with sex’chromosome anomalies. Child Dev 53:1182 -1192. 147. Morse HG, Heideman R, Hays T, Robinson A (1982): 4;11 translocation in acute lymphoblastic leukemia: A specific syndrome. Cancer Genet Cytogenet 7:165-172. 148. Robinson A (1982): Book review: Trisomy 21, edited by G.R. Burgio, M. Fraccaro, L. T~epolo,and U. Wolf. Am J Hum Genet 34576. 149. Morse HG, Hays T, Patterson D, Robinson A (1982): Giemsa-11 technique: Applications in the chromosomal characterization of hematological specimens. Hum Genet. 61:141-144. 150. Robinson A (1982):a. Trisomy X female (47,XXX),pp 552-553; b. 46,XX male, pp 555-557; c. 47,XXY Male, Klinefelter syndrome, pp 557-558; d. 48,XXXY, Klinefelter variant, pp 559-560; e. 49,XXXXY syndrome, pp 560-562; f. 48,XXYY and 49,XXXYY Klinefelter variants, pp 562-564. In Myrianthopoulos NC (ed): “Handbook of Clinical Neurology, Vol. 43, Neurogenetic Directory, Part TI.” Amsterdam: Elsevier. 151. Robinson A, Bender B, Borelli J, Puck M, Salbenblatt J, Webber ML (1982):Sex chromosomal abnormalities (SCA):A prospective and longitudinal study of newborns identified in an unbiased manner. In Stewart DA (ed): “Children With Sex Chromosome Aneuploidy: Follow-up Studies. New York Alan R. Liss, Inc., for the National Foundation-March of Dimes. BD:OAS 18(4):7-39. 152. Bender BG, Puck MH, Salbenblatt JA, Robinson A (1983): Hemispheric organisation in 47,XXY boys. Lancet 1:132. 153. Bender B, Fry E, Pennington B, Puck M, Salbenblatt J, Robinson A (1983): Speech and language development of 41 children with sex chromosome anomalies. Pediatrics 71:262-267. 154. Robinson A, Bender B, Borelli J , Puck M, Salbenblatt J (1983): Sex chromosomal anomalies: Prospective studies in children. Behav Genet 13:321-329. 155. Puck MH. Bender BG. Borelli JB. Salbenhlatt JA. Robinson A (1983): Parents’ adaptation to early diagnosis of sex’chromosome anomalies. Am J Med Genet 16:l-79. 156. Morse HG, Odom LF, Tubergen D, Hays T, Blake M. Robinson A (1983):Prognosis in acute lymphoblastic leukemia of childhood as determined by cytogenetic studies at diagnosis. Med Pediatr OnC O ~11.310-318. 157. Bayless-Underwood L, Cho S, Ward B, Robinson A (1983): Two cases of satellited Yq chromosome. Clin Genet 24:359- 364. 158. Iselius L. (24 authors including A Robinson) (1983):The llq;22q translocation: A collaborative study of 20 new cases and analysis of 110 families. Hum Genet 64:343- 355. 159. Robinson A (1983):Foreword. In HagermanRJ, McBogg PM (eds): “Fragile X Syndrome: Diagnosis, Biochemistry, and Intervention.” Dillon, Colo.: Spectra Publishing Co. 160. Robinson A (1984):Review of genetic concepts. Ch 14,pp 131-139; Genetic consequences of radiation exposure. Ch 15, pp 141-145. In Hendee WR ied): “Health Effects of Low-Level Radiation.” Norwalk, Conn.: Appleton-Century-Crofts. 161. Bender B, Puck M, Salbenblatt J , Robinson A (1984): Cognitive development of unselected girls with complete and partial X monosomy. Pediatrics 73:175-182. 162. Bender BG, Puck MH, Salbenblatt JA, Robinson A (1984): The development of four unselected 47,XYY boys. Clin Genet 25:435-445. 163. Robinson A (1984): Principles of heredity and genetics (Revision). In “Encyclopaedia Britannica.” Chicago: Encyclopaedia Britannica, Inc. 164. Robinson A (1984):Birth defects and congenital disorders (Revi-
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sion). In “Encyclopaedia Britannica.” Chicago: Encyclopaedia Britannica, Inc. 165. Robinson A, Goodman SI, O’Brien D (1984): Genetic and chromosomal disorders, including inborn errors of metabolism. In Kempe CH, Silver HK, O’Brien D (eds):“Current Pediatric Diagnosis and ‘keatment,” 8th edition. Los Altos, Calif.: Lange Medical Publications, ch 33, pp 992-1030. 166. Robinson A (1984): Book review: Issues and Reviews in Teratology, Vol. I, edited by H. Kalter. Am J Hum Genet 36:721-722. 167. Borelli JB, Bender BG, Puck MH, Salbenblatt, JA, Robinson A (1984):The meaning of early knowledge of a child’s infertility in families with 47,XXY and 45,X children. Child Psychiatry Hum Dev 14:215-222. 168. Salbenblatt JA, Bender BG, Puck MH, Robinson A, Faiman C, Winter JSD (1985): Pituitary-gonadal function in Klinefelter syndrome before and during puberty. Pediatr Res 19232-86. 169. Robinson A, Bender B, Borelli J, Puck M, Salbenblatt J (1985): Sex chromosomal anomalies: Prospective studies in children. In Chess S, Thomas A (eds): “Annual Progress in Child Psychiatry and Child Development, 1984. New York: BrunnerMazel, pp 133-142. (Republished from Behav Genet 13:321-329,1983, as an outstanding contribution to the understanding and treatment of the normal and disturbed child.) 170. Robinson A, Henry GP (1985): Prenatal diagnosis by amniocentesis. Annu Rev Med 36:13-26. 171. Robinson A, Bender BG, PuckMH, SalbenblattJA (1985):Growth and development of children with a 47,XYY karyotype. In “The Y Chromosome, Part B: Clinical Aspects of Y Chromosome Abnormalities.” Progress and Topics in Cytogenetics, Vol. 6B. Sandberg AA (ed):New York: Alan R. Liss, Inc., pp 265-275. 172. Robinson A (1986): Genetics and heredity. In “Encyclopaedia Britannica.” Chicago: Encyclopaedia Britannica, Inc. 173. Bradley DM, Patterson L), Robinson A (1986): Somatic Cell genetic studies on a family with Down syndrome due to an unusual translocation (21q22 2lqter). Tris 21 1:41-52. 174. Bender BG, Puck MH, Salbenblatt JA, Robinson A (1986): Cognitive development of children with sex chromosome abnormalities. In Smith S (ed): “Genetics and Learning Disabilities.” San Diego: College Hill Press, pp 175-201. 175. Robinson A, Bender BG, Borelli JB, Puck MH, Salbenblatt JA, Winter JSD (1986): Sex chromosomal aneuploidy: Prospective and longitudinal studies. In: “Prospective Studies on Children With Sex Chromosome Aneuploidy.” Ratcliffe SG, Paul N p (eds): New York: Alan R. Liss, Inc., for the National FoundationMarch of Dimes. BD:OAS 22(3):23-71. 176. Bender BG, Puck MH, Salbenblatt JA, Robinson A (1986): Dyslexia in 47,XXY boys identified at birth. Behav Genet 16:343-354. 177. Robinson A (1986):Book review: Fragile Sites on Human Chromosomes, by G.R. Sutherland and F. Hecht. Q Rev Biol 61:263. 178. Salbenblatt JA, Meyers DC, Bender BG, Linden MG, Robinson A (1987): Gross and fine motor development in 47,XXY and 47,XYY males. Pediatrics 80:240-244. 179. Morse HG, Odom LF, Castro R, Hays T, Blake M, Vannais D,
180.
181. 182. 183.
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191. 192. 193. 194.
Robinson A (1987): Methodology of premature chromosome condensation and its potential for relapse prediction in acute leukemia of children and adolescents. Cancer Genet Cytogenet 27:51-61. Morse HG, Odom LF, Castro R, Hays T, Blake M, Vannais D, Robinson A (1987): Premature chromosome condensation as a predictive indicator of relapse in children and adolescents with acute leukemia: Initial observations. Cancer Genet Cytogenet 27:63-72. Bender BG, Linden MG, Robinson A (1987): Environment and developmental risk in children with sex chromosome abnormalities. J Am Acad Child Adolesc Psychiatry 26499-503. Robinson A (1987): Genetics and the future of medicine. Somatic Cell Mol Genet 13(4):485-489. Smith ACM, Spuyler K, Williams TM, McConnell T, Sujansky E, Robinson A (1987): Genetic risk for recombinant 8 syndrome and the transmission rate of balanced inversion 8 in the Hispanic population of the southwestern United States. Am J Hum Genet 41:1083-1103. Wheeler M, PeakmanD, Robinson A, Henry G (1988):45,X/46,XY mosaicism: Contrast of prenatal and postnatal diagnosis. Am J Med Genet 29565-571. Robinson A (1988):Introduction: Genetics and the health professional. In “Genetic Applications: A Health Perspective.” Lawrence, Kansas: Learner Managed Designs, pp 1-3. Linden MG, Bender BG, Harmon FLJ, Mrazek DA, Robinson A (1988):47,XXX: What is the prognosis? Pediatrics 82619-630. Ward BE, Hayden MW, Robinson A (1988): Isochromosome 12p mosaicism (Pallister-Killian syndrome): Newborn diagnosis by direct bone marrow analysis. Am J Med Genet 31:835-839. Bender BG, Linden MG, Robinson A (1989): Verbal and spatial processing eficiency in 32 children with sex chromosome abnormalities. Pediatr Res 25577-579. Robinson A (in press): Demography and prevalence ofl’urner’s. In Rosenfeld R, Grumbach M (eds): ‘‘Turner Syndrome.” New York: Marcel Dekker, Inc. Bender BG, Linden M, Robinson A (in press): SCA In search of developmental patterns. In Berch D, Bender B (eds): “Sex Chromosome Abnormalities and Behavior: Psychological Studies.” Washington, D.C.: Westview Press and American Association for the Advancement of Science. Salbenblatt JA, Meyers DC, Bender BG, Linden MG, Robinson A (in press): Gross and fine motor development in 45,X and 47,XXX females. Pediatrics. Robinson A, Bender BG, Linden MG (in press): Decisions following the intrauterine diagnosis of sex chromosome aneuploidy. Am J Med Genet. Robinson A (in press): Book review: Proceed with Caution: Predicting Genetic Risks in the Recombinant DNA Era, by Neil A. Holtzman. The Pharos. Robinson A, Bender BG, Linden MG, Salbenblatt JA (in press): Sex chromosome aneuploidy: The Denver prospective study. Birth Defects.
Arthur Robinson-An
Appreciation
John M. Opitz Department of Medical Genetics, Shodair Hospital, Helena, Montana the Denver report. Arthur Robinson’s pioneering work on the prevalence of gonosomal aneuploidy at birth, the carrier detection of galactosemia, the natural history of (prospectively ascertained) children with sex chromosome abnormalities, amniocyte culture, and prenatal diagnosis stands as a classic accomplishment in the field. However, Art deserves equal recognition for his leadership in the teaching of clinical genetics and genetic counseling, the establishment of cytogenetics laboratories and genetics clinics which set earliest local and regional standards of highest quality, for graduate and postgraduate teaching of clinical genetics and cytogenetics, and for his role in chairing the Department of Biophysics and Genetics a t the University of Colorado, all of which have made Art the Dean of Rocky Mountain Cytogenetics and Clinical Genetics. Rare is the person as able to embody the best aspects of clinical and basic human biology while growing in personal and professional stature. Modesty prevented Arthur from mentioning the several important awards he has received for his long and distinguished career in pediatrics and genetics at the University of Colorado and the National Jewish Center for Immunology and Respiratory Medicine in Denver. These include the Gerald J . Hencman Memorial Award of the National Foundation-March of Dimes and the Virginia Apgar Memorial Award of the Metro Denver March of Dimes, the Centennial Award for DistinWhen Arthur Robinson entered Columbia University guished Service to the University of Colorado School of to study classics at the age of 16 he “sufferedfrom imma- Medicine, the Arthur B. Lorber Distinguished Service turity and a poor self-image.” At the age of 75, Dr. Award from the Council of National Trustees and Board Robinson has been ennobled by a serenity and dignity of Directors of the National Jewish HospitaUNational granted to few and experienced as a benediction by all Asthma Center in Recognition of Extraordinary who meet him. In the 28 years I have known Art, as he is Achievement to Advance Medical Service, and the Boncalled affectionately, I have always considered myself fils-Stanton Foundation Award for Significant and privileged by every contact with him, and have been Unique Contributions in the Field of Science and Mediguided and inspired by Art’s standards in clinical and cine. In 1980 and 1985 Arthur received Medical Student pediatric genetics and in applied basic sciences. Art was Awards for Excellence in Teaching and on May 21,1986, the f i r s h r one of the first-to discover the chromo- he was asked to present a Distinguished Faculty Semisome aberration in the Ullrich-Turner syndrome. His nar at the University of Colorado. In part, the 1945 need t o protect the confidentiality of the first patient he citation by HQ of the 78th Infantry Division of the U S . studied was responsible for the delay in publication of Army for Award of Bronze Star Medal and of Air Medal with Oak Leaf Cluster reads: “His leadership and outstanding devotion to duty are in accordance with the Received for publication December 27, 1988; revision received highest military traditions.” September 22, 1989. Clinical genetics, pediatric genetics and cytogenetics, Address reprint requests to: John M. Opitz, M.D., Shodair Hospiand the University of Colorado have been greatly ental, Department of Medical Genetics, P.O. Box 5539, 840 Helena riched by the work of Arthur Robinson. In the American Avenue, Helena, MT 59604.
0 1990 Wiley-Liss, Inc.
Arthur Robinson-An Appreciation
West we are proud of Arthur as the Dean in our field and grateful to have been able to benefit from his advice and consultation for over 30 years. Dr. Robinson’s bibliography is appended in the happy knowledge that this continues to be a mowing list.
PUBLICATIONS: Arthur Robinson, M.D. 1. Bullowa JGM, Alterman J , Katana N, Scannell M, Robinson A (1942): Pertussis immunitv with toxin and antitoxin. J Am Med ASSOC120:886-890. 2. Robinson A, Howard J E (1948):Atresia ofthe tricuspid valve with transoosition of the meat vessels. Am J Dls Child 75575-581. 3. Howird J E , Robinson A (1948): Acute osteomyelitis of the superior maxilla in infants. J Mt Sinai Hasp 15:101-104. 4. Laff HI, Hurst A, Robinson A (1951): Importance of bronchial involvement in primary tuberculosis of childhood. J Am Med Assac 146:778-783. 5. Public Health Service Cooperative Investigation (1953): Chemotherapy of miliary tubercuiosis and tubercaous meningitis. Pediatrics 12:38-55. 6. Robinson A, and Ro YH (1 954): Tuberculous meningitis in infants and children. Am J Dis Child 87:139-155. 7. Meyer M, Middlebrook G, Robinson A (1955): The treatment of primary tuberculosis in infancy. J Pediatr 46:398-402. 8. Meyer M, Robinson A, Middlebrook G, Alway R (1955): Possible immediate deleterious effect of isoniazid on course of tuberculous meningitis. Am Rev Tuberc 71:765. 9. Robinson A, Meyer M, Middlebrook G (1955):Tuberculin hypersensitivity in tuberculous infants treated with isoniazid. N Engl J Med 252:983-985. 10. Robinson A, Meyer M (1956): The effect of specific therapy in primary tuberculosis of the child. J Pediatr 48:705-709 11. U.S. Public Health Service Tuberculosis Prophylaxis Trial (1957): Prophylactic effects of isoniazid on primary tuberculosis in children. Am Rev Tuberc 76:942-963. 12. Robinson A (1957):Pulmonary tuberculosis: The primary lesion. Pematr Clin North Am 255-270. 13. Lanier VS, Russell WF, Heaton A, Robinson A (1958):Concentrations of active isoniazid in serum and cerebrospinal fluid of patients with tuberculosis treated with isoniazid. Pediatrics 21:910-915. 14. Puck TT, Cieciura SJ, Robinson A (1958): Genetics of somatic mammalian cells. 111.Long-term cultivation of euploid cells from human and animal subjects. J Exp Med 108:945-956. 15 Qio JH, Puck TT, Robinson A (1959): Chromosomes of human subjects with genetic defects. Anim Cell Inf Serv Newslett No. 1. 16. Puck TT, Robinson A, Tjio J H (1959): The chromosomal constitution of human subjects with genetic diseases. 11. Treacher-Collins Syndrome (mandibulo-facial dysostosis). Anim Cell Inf Serv Newslett l(2). 17. Puck TT, Robinson A, Tjio J H (1959):The genetic defect in testicular feminization. Anim Cell Inf Serv Newslett l(3). 18. Tjio JH, Puck TT, Robinson A (1959):The somatic chromosomal constitution of some human subjects with genetic defects. Proc Natl Acad Sci USA 45:1008-1016. 19. Committee of the Section on Diseases of the Chest, American Academy of Pediatrics (1959): Primary bacterial resistance in tuberculosis. Pediatrics 24:493-494. 20. Robinson A (1959): Simplified fixation and staining for delineation of nuclear chromatin by the Barr technique. Pedatrics 24:858-859. 21. Puck TT, Robinson A (1960): Additional chromosomal satellites in man. Anim Cell Inf Serv Newslett 2(3). 22. Puck TT, Robinson A, Tjio J H (1960):Familial primary amenorrhea due to testicular feminization: A human gene affecting sex differentiation. Proc Sac Exp Biol Med 103:192-196. 23. Tjio J H , Puck TT, Robinson A (1960):The human chromosomal satellites in normal persons and in two patients with Marfan’s syndrome. Proc Natl Acad Sci USA 46:532-539. 24. Robinson A (1960): How much is too much? Am J Dis Child 100:1-2. 25. Robinson A, et al. (14 signatories) (1960-1961): A proposed standard system of nomenclature of human mitotic chromosomes. JAMA 174:159-162. Am J Hum Genet 12:384-388. Cerebral Palsy Bull (Suppl), 2(3):1-9. J Hered 51(5):214-221. Pediatrics 27:485-488.
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26. Robinson A (1961): The human chromosomes. Am J Dis Child 101:379-398. 27. Robinson A (19621: The diagnosis of galactosemia and galactosemia carriers. Anim Cell Inf Serv Newslett 3:7. 28. Robinson A (1962): The culture of peripheral leukocytes for chromosomal analysis using small amounts of blood. Anim Cell Inf Serv Newslett 3:8. 29. Robinson A (1962): Genetics. The New Physician, Special Issue, p. 237. 30. Robinson A, et al. 11963):Participant: The London Conference on the Normal Human Karyotype CIBA Foundation; Guest Symposium, International Study Group on Human Chromosomes, London, August 28-30, 1963. Cytogenetics 2:264-268. 31. Robinson A (1963): The assay of galactokinase and galactose-lphosphate uridyl transferase activity in human erythrocytes: A presumed test for heterozygous carriers of the galactosemic defect. J Exp Med 118:359-370. 32. Robinson A, Puck TT (1964): Nuclear chromatin studies in newborn infants. Anim Cell Inf Serv Newslett 5:4-5. 33. Robinson A, Puck TT (1964): Procedure for sex chromatin determination in newborns by means of buccal smears. Anim Cell Inf Serv Newslett 5:1 -2. 34. Robinson A, Puck TT (1964):A procedure for sex chromatin determination in newborns by means ofamnion biopsies. Anim Cell Inf Serv Newslett 53. 35. Robinson A, Priest RE, Bigler PC (1964): Male pseudohermaphrodite with X Y K O mosaicism and bilateral gonadoblastomas. Lancet 1:111-112. 36. Robinson A, Puck TT (1965): Sex chromatin in newborns: Presumptive evidence for external factors in human nondisjunction. Science 148:83-85. 37. Robinson A (1965j: Book review: Human Chromosome Methodology, edited by Jorge Yunis. Science 150:1704. 38. Randall DL, Reiquam CW, Githens JH, Robinson A (1965): Familial myeloproliferative disease: A new syndrome closely simulating myelogenous leukemia in childhood. Am J Dis Child 110:479-500. 39. Robinson A (1966): Clinical genetics. In Taylor ES (ed): “Beck‘s Obstetrical Practice, Eighth Edition.” Baltimore: Williams & Wilkins, ch 49, pp 621-640. 40. Robinson A, Puck TT (1966): Infectious hepatitis and Down’s syndrome. Lancet 1:313. 41. Robinson A (1966):Genetic counseling. S Dakota J Med 19:27-29 42. Robinson A (1966): Participant and Signatory: Standardization in Human Cytogenetics. National Foundation-March of Dimes, Chicago Conference, 2C2). 43. Robinson A, Puck TT (1967):Studies on chromosomal nondisjunction in man. 11. Am J Hum Genet 19:112-129. 44. Priest JH, Robinson A (1967): Dermatoglyphics in Down’s syndrome and congenital rubella. Lancet 1:683. 45. Snyder RD, Robinson A (1967): Leucine-induced hypoglycemia. Am J Dis Child 113566-570. 46. Puck TT,Robinson A (1967): Some perspectives in human cytogenetics. In Keller W (ed): “Biologic Basis of Pediatric Practice.” ch 144, pp 1407-1421. 47. Robinson A, Puck ‘IT (1967): Medicine and the human chromosomes. In Zubin J, Jervis GA (eds): “Psychopathology of Mental Development.” New York Grune and Stratton, pp 1-14. 48. Robinson A (1967):Book review: Chromosome Studies on Adults, by W.M. Court Brown, K.E. Buckton, P.A. Jacobs, I.M. Tough, E.B. Kuenssberg and J.D.E. Knox. Q Rev Biol42539. 49. Fulginiti VA, Kempe CH, Hathaway WE, Pearlman DS, Sieber OF, Eller JJ, Joyner JW, Sr., Robinson A (1968): Progressive vaccinia in immunologically-deficient individuals. Birth Defects 4(1):128-150. 50. Stewart J, Go S, Ellis E, Robinson A (1968): IgA and partial deletions of chromosome 18. Lancet 2:779. 51. Ott J E , Robinson A, Peakman DC (1968): DID balanced translocations. Lancet 2:1352. 52. Ott J E , Robinson A (1969): Cerebral gigantism. Am J Dis Child 117:357-368. 53. Githens JH, Muschenheim F, Fulginiti VA, Robinson A, Kay HEM (1969): Thymic alymphoplasia with XXlXY lymphoid chimerism secondary to probable maternal-fetal transfusion. J Pediatr 75:87-94. 54. Cherington M, Ott JE, Robinson A (1969): Cornelia de Lange syndrome in an adult male. Neurology 19:879-884. 55. Chemke J, Robinson A (1969): The third fontanelle. J Pediatr 75:617-622. 56. Robinson A, Goad WB, Puck TT, Harris J (1969): Studies on chromosomal nondisjunction in man. 111. Am J Hum Genet 21:466-485.
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57. Robinson A (1969): Sex differences in development. Dev Med Child Neural 11:245-246. 58. Snyder R, Robinson A (1969): Recessive sex-linked mental retardation in the absence of other recognizable abnormalities. Report of a family. Clin Pediatr 8:669-674. 59. Robinson A (1969):Medicine and the human chromosomes. Proc. Dimensions of Nutrition, Ft. Collins, Colo., July 7-11. 60. Robinson A (1969): Introductory comments on carbon 14 methods. In Hsia DY-Y ied): “Galactosemia.” Springfield: Charles C. Thomas, pp 94-97. 61. Robinson A (1969):Introduction: The Etiology and Epidemiology of Meningomyelocele and Anencephaly. Roc. Natl. Fndn. Spina Bifida Symposium, Denver, Colo., nov. 24-26. 62. Robinson A (1970): Genetic and chromosomal disorders. In Kempe CH, Silver HK, O’Brien D (eds): “Current Pediatric Diagnosis and Treatment.” Los Altos, Calif.: Lange Medical Publications, ch 32, pp 698-719. 63. Stewart Jhl, Go S, Ellis E, Robinson A (1970): Absent IgA and deletions of chromosome 18. J Med Genet 7:ll-19. 64. Priest JH, Peakman DC, Patil S, Robinson A (1970):Significance of chromosome 17ps + in three generations of a family. J Med Genet 7:142-147.65. Chemke J, Carmichael R, Stewart JM, Geer RH, Robinson A (1970): Familial XY gonadal dysgenesis. J Med Genet 7:105-111. 66. Claman HN, Merrill DA, Peakman D, Robinson A (1970):Isolated severe gamma A deficiency: Immunoglobulin levels, clinical disorders, and chromosome studies. J Lab Clin Med 75:307-315. 67. Kohn G, Robinson A (1970): Tetraploidy in cells cultured from amniotic fluid. Lancet 2:778-779. 68. Chemke J, Robinson A (1970): The third fontanelle. El Medico 20:36-37. 69. Chemke J , Robinson A (1971): The inheritance of a structural anomaly of one chromosome no. 16 in a kindred (46,16- ,C + 1. J Med Genet 8:346-350. 70. Eller E, Frankenburg W, Puck M, Robinson A (19711:Prognosis in newborn infants with X-chromosomal abnormalities. Pediatrics 47:681-688. 71. Nakashima I. Robinson A (1971): Fertility in a 45,X female. Pediatrics 47:770-773. 72. Harris JS, Robinson A (1971):X-chromosome abnormalities and the obstetrician. The value of routine nuclear sexing of newborns. Am J Obstet Gynecol 109574-583. 73. Humbert JR, Hathaway WE, Robinson A, Githens J H , Peakman DC (1971):Re-leukemia in children with a missing bone marrow C chromosome and a myeloproliferativedisorder. Br J Haematol 21:705-716. 74. Greensher A, Gersh R, Peakman D, Robinson A (1971):Fluorescence of the Y and Barr body in human interphase cells. Lancet I
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75. Greensher A, Gersh R, Peakman D, Robinson A (1971): Screening of newborn infants for abnormalities of the Y chromosome. J Pediatr 79:305-306. 76. Greensher A, Gersh R, Peakman D, Robinson A (1971): Intrauterine diagnosis of fetal sex. Pediatrics 48:159. 77. RobinsonA (1971): Book review: Genetic Disorders ofMan. edited by R.M. Goodman. Science 172:463. 78. Robinson A (1971): Clinical genetics. In Taylor ES (ed): “Becks Obstetrical Practice,” Ninth Edition. Baltimore: Williams and Wilkins, ch 49, pp 626-646. 79. Robinson A (1971): Genetics and society. Utah Law Rev 1971(4):487-492. 80. Robinson A, Puck M, Droegemueller W, Goodman S (1972):Intrauterine diagnosis of birth defects. In Klingberg MA, Abramovici A, Chemke J (eds): “Drugs and Fetal Development.” Advances in Experimental Medicine and Biology, Val. 27. Xew York Plenum Press, pp 419-425. 81, Greensher A, Gersh R, Peakman D, Fbbinson A (1972): Screening for abnormalities of the Y chromosome. J Pediatr 80:158. 82. Robinson A (1972): Genetic and chromosomal disorders. In Kempe CH, Silver HK, O’Brien D (eds):“Current Pediatric Diagnosis and Treatment,” Second Edition. Los Altos, Calif.: Lange Medical Publications, ch 34, pp 846-868. 83. Robinson A, Bowes W, Droegemueller W, Puck M, Goodman S, Shikes R, Greensher, A (1973):Intrauterine diagnosis: Potential complications. Am J Obstet Gynecol 116:937-941. 84. Robinson A (1973): Chromosomal disorders. In StfYe.HK, Kempe CH, Bruyn HB (eds): “Handbook of Pediatrics, Tenth Edition. Los Altos, Calif.: Lange Medical Publications, pp 652-654. 85. Robinson A (1973): Intrauterine diagnosis and ultrasound. Lancet 2:1504. 86. Robinson A, OBrien D (1974): Genetic and chromosomal disorders, including inborn errors of metabolism. In Kempe CH, Silver
HK, OBrien D (eds): “Current Pediatric Diagnosis and Treatment,” Third Edition. Los Altos, Calif.: Lange Medical Publications, ch 33, pp 859-899. 87. Reynolds B, Puck M, Robinson A (1974): Genetic counseling: An aaaraisal. Clin Genet 5:177-187. 88. %binson A (1974): Book review: Genetics of Sex Differentiation, by Ursula Mittwoch. Am Sci 62(3):362. 89. Robinson A, Puck M, Tennes K (1974): The 47,XXY karyotype. - - _ Lancet 1:1343. 90. Robinson A (1974):Neonatal deaths and sex chromosome anomalies. Lancet 1:1223. 91. Riccardi VM, Robinson A (1974): Regional genetic counseling. Rocky Mtn Med J 71:686-688. 92. Puck M, Tennes K, Frankenburg W, Bryant K, Robinson A (1975): Early childhood development of four boys with 47,XXY karyotype. Clin Genet 7:8-21. 93. Riccardi V, Robinson A 11975): Preventive medicine through genetic counseling: A regional program. Prev Med 4:126-134. 94. RobinsonA (1975):Sex chromatin in newborns. Am J Hum Genet 27:118. 95. Tennes K, Puck M, Bryant K, hankenburg W, Robinson A (1975): A developmental study of girls with trisomy X. Am J Hum Genet 27:71-80. 96. Robinson J, Tennes K, Robinson A (1975): Amniocentesis: Its impact on mothers and infants. A one-year follow-up study. Clin Genet 8:97-106. 97. Hecht F, McCaw BK, Peakman D, Robinson A (1975): Non-randam occurrence of 7-14 translocations in human lymphocyte cultures. Nature 255:243-244. 98. Peakman DC, Moreton MF, Robinson A (1975): Chromosomal mosaicism in diagnostic amniotic fluid cell cultures. Pediatr Res 9516. 99. Karsh RB, Knapp RF, Nora JJ, Wolfe RR, Robinson A (1975): Congenital heart disease in 49,XXXXY syndrome. Pediatrics 56:462-464. 100. Hays T, Humbert JR, Peakman DC, Hutter JJ, Morse HG, Robinson A, August CS (1975): Missing Y chromosome in juvenile chronic myelogenous leukemia. Humangenetik 29:259-264. 101. Goad WB, Robinson A, Puckl”(1976): Incidence ofaneuploidy in a human population. Am J Hum Genet 28:62-68. 102. Peakman DC, Robinson A (1976): Indications for chromosome analysis: Effect of new bandingtechniques. J Pediatr 88:166-167. 103. Robinson A (1976): Clinical genetics. In Taylor ES (ed): “Beck’s Obstetrical Practice and Fetal Medicine,” Tenth Edition. Baltimore: Williams and Wilkins, ch 47, pp 605-627. 104. Robinson A (1976): Genetic counseling. In Fenoglio CM, Goodman R, King DW (eds): “Developmental Genetics,” Advances in Pathology, No. 3. New York: Stratton Intercontinental Medical Book Corp., pp 95-101. 105. Robinson A, Goodman SI, O’Brien D (1976): Genetic and chromosomal disorders, including inborn errors of metabolism. In Kempe CH, Silver HK, O’Brien D (eds):“Current Pediatric Diagnosis and Treatment,” 4th Edition. Los Altos, Calif.: Lange Medical Publications, ch 33, pp 885-926. 106. Verma RS, Peakman DC, Robinson A, Lubs HA (1976): Comparison of G, Q, and R banding in 28 cases of chromosomal abnormalities. Cytogenet Cell Genet 16:479-486. 107. Henry G, Wexler P, Robinson A (1976):Rh-immune globulin after amniocentesis for genetic diagnosis. Obstet Gynecol48:557-559. 108. Peakman DC, Moreton MF, Robinson A (197’7): Prenatal diagnosis: Techniques used to aid in ruling out maternal cell contamination. J Med Genet 14:37-39. 109. Robinson A, Peakman DC (1977):Chromosome abnormalities. In Rudolph AM (ed): “Pediatrics,” 16th Edition. New York Appleton-Century-Crofts, pp 279-291. 110. Henry GP, Robinson A (1977): Equivocal amniotic fluid alphafetoprotein levels in prenatal diagnosis of neural tube defects. Am J Obstet Gynecol 127:204. 111. Tennes K, Puck M, Orfanakis D, Robinson A (1977): The early childhood development of 17 boys with sex chromosome anomalies. A prospective study. Pediatrics 59:574-583. 112. Robinson A (1977): Studies on infants and children with sex chromosomal abnormalities. In Borek C, Fenoglio CM, King DW (eds): “Cancer Biology. IV. Differentiation and Carcinogenesis.” Advances in Pathobiology, No. 6. New York: Stratton Intercontinental Medical Book Corp., pp 214-226. 113. Verma RS, Peakman DC, Robinson A, Lubs HA (1977): Two cases of Down syndrome with unusual de novo translocation. Clin Genet 11227-234. 114. Morse HG, Humbert JR, Hutter J J , Robinson A (1977): Karyotyping of bone-marrow cells in hematologic diseases. Hum Genet 37:33-39.
Arthur Robinson-An Appreciation 115. Ziter FA, Wiser WC, Robinson A (1977): Three-generation pedigree of a mobius syndrome variant with chromosome translocation. Arch Neurol 34:437-442. 116. Robinson A (1977): Book review: Population Cytogenetics: Studies in Humans, edited by E.B. Hook and I.H. Porter. Am J Hum Genet 29:548-549. 117. Robinson A (1977): Education of community physicians and paramedical genetics personnel (postgraduate training). In Lubs HA, de la Cruz F (eds): “Genetic Counseling.” New York: Raven Press, pp 369-375. 118. Rohinson A, Puck TT (1977): Trisomy clusters. Lancet 2:981-982. 119. Robinson A, Goad WB, Puck TT (1978): Some epidemiologic aspects of chromosomal aneuploidy. In Cohen BH, Lilienfeld AM, Huang PC (eds):“Genetic Issues in Public Health and Medicine.” Springfield: Charles C. Thomas, pp 206-214. 120. Robinson A, Goodman SI, O’Brien D (1978): Genetic and chromosomal disorders, including inborn errors in metabolism. In Kempe CH, Silver HK, O’Brien D (eds):“Current Pediatric Diagnosis and Treatment,” 5th Edition. Los Altos, Calif.: Lange Medical Publications, ch 33, pp 931-972. 121. Henry GP, Robinson A (1978): Prenatal genetic diagnosis. Clin Obstet Gynecol 21(2):329-340. 122. Morse HG, Ducore JM, Hays T, Peakman D, Robinson A (1978): Multiple leukemic clones in acute leukemia of childhood. Hum Genet 40:269-278. 123. Humbert JR. Morse HG. Hutter JJ, Rose B, Robinson A (1978): Non-leukemic dividing cells in the blood of leukemic patients. Am J Hematol4:217-224. 124. Henry GP, Peakman DC, Robinson A (1978): Prenatal genetic diagnosis: Nine years’ experience. Obstet Gynecol Surv 33569-577. 125. Ward BE, Cook RH, Robinson A, Austin J H (1979): Increased aneuploidy in Alzheimer disease. Am J Med Genet 3:137-144. 126. Hays T, Morse H, Peakman D, Rose B, Robinson A (1979): Cytogenetic studies of chronic myelocytic leukemia in children and adolescents. Cancer 44:2 10- 2 14. 127. Morse H, Hays T, Peakman D, Rose B, Robinson A (1979): Acute nonlymphohlasticleukemiain childhood High incidence of clonal abnormalities and non-random changes. Cancer 44:164-170. 128. Robinson A, Puck M, Pennington B, Borelli J, Hudson M (1979): Abnormalities of the sex chromosomes: A prospective study on randomly identified newborns. In Robinson A, Lubs HA, Bergsma D (eds): “Sex Chromosome Aneuploidy: Prospective Studies on Children.” New York: Alan R. Liss, Inc., for the National Foundation-March of Dimes, BD:OAS 15(1):203-241. 129. Rohinson A, Lubs HA, BergsmaD (eds) (1979): “Sex Chromosome Aneuploidy: Prospective Studies on Children.”New York Alan R. Liss, Inc., for the National Foundation-March of Dimes. BD:OAS 15(1). 130. Peakman DC, Moreton MF, Corn BJ, Robinson A (1979):Chromosomal mosaicism in amniotic fluid cell cultures. Am J Hum Genet 31:149-155. 131. Findley L, Kurnick J E , Peakman DC, Robinson A (1979): Chromosome deletion 46.XX.de1(20Koll) in anogenic mveloid metaplasia. Hum Genet 47:207-212. 132. Morse H, Hays T, Rose B, Robinson A (1979): Chromosome 1 abnormalities in relapse and terminal stages in childhood leukemia. Med Pediatr Oncol 7:9-16. 133. Hecht F, Kaiser-McCaw B: Peakman D, Robinson A (1979): New translocations in human lymphocytes: A mutagen monitoring system. Environ Health Perspect 31:19-22. 134. Pennington B, Puck M, Robinson A (1980): Language and cognitive development in 47,XXX females followed since birth. Behav. Genet 10:31-41. 135. Robinson A, Goodman SI, OBrien D (1980): Genetic and chromosomal disorders including inborn errors of metabolism. In Kempe CH, Silver HK, O’Brien D (eds):“Current Pediatric Diagnosis and Treatment,” 6th Edition. Los Altos, Calif.: Lange Medical Puhlications, ch 33, pp 947-987. 136. Ward BE. Henrv GP. Robinson A (1980): Cvtogenetic studies in 100 couples with recurrent spontaneous aiorgons. Am J Hum Genet 32549-554. 137. Robinson A et al. (1980):Participant. The XYY controversy: Researching violence and genetics. Hastings Cent Rep [Spec Supplj. 138. Ward BE, Bradley CM, Cooper JB, Rohinson A (1981): Homodicentric chromosomes: A distinctive type of dicentric chromosome. J Med Genet 18:54-58. 139. Strain J E , Smith ACM, Ward BE, Robinson A (1981): Inverted tandem duplication of the middle segment of the long arm of chromosome 14. Pediatrics 67:273-276. 140. Hecht F Peakman DC, Kaiser-McCaw B, Robinson A (1981):
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Amniocyte clones for prenatal cytogenetics. Am J Med Genet 10:51-54. 141. Salbenblatt JA, Bender BG, Puck MH, Robinson A, Webber ML (1981):Development ofeight pubertal males with 47,XXY karyotype. Clin Genet 20:141-146. 142. Sujansky E, Smith ACM, Peakman DC, McConnell TS, Baca P, Robinson A (1981): Familial pericentric inversion of chromosome 8. Am J Med Genet 10:229-235. 143. Hays T, Morse HG, Robinson A (1981):9;22;15 complex translocation in Ph’ chromosome positive CML revealed by Giemsa-11 procedure in apparent lymphoid cells of blastic crisis. Cancer Genet Cytogenet 4:283-292. 144. Robinson A, Goodman SI, O’Brien D (1982): Genetic and chromosomal disorders, including inborn errors of metabolism. In Kempe CH, Silver HK, O’Brien D (eds):“Current Pediatric Diagnosis and Treatment,” 7th Edition. Los Altos, Calif.: Lange Medical Publications, ch 33, pp 934-972. 145. Webber ML, Puck MH, Maresh MM, Goad WB, Robinson A (1982): Skeletal maturation of children with sex chromosome abnormalities. Pediatr Res 16:343-346. 146. PenninPton BF. Bender B. Puck M. Salbenblatt J. Robinson A (1982):“Learning disabilities in chiidren with sex’chromosome anomalies. Child Dev 53:1182 -1192. 147. Morse HG, Heideman R, Hays T, Robinson A (1982): 4;11 translocation in acute lymphoblastic leukemia: A specific syndrome. Cancer Genet Cytogenet 7:165-172. 148. Robinson A (1982): Book review: Trisomy 21, edited by G.R. Burgio, M. Fraccaro, L. T~epolo,and U. Wolf. Am J Hum Genet 34576. 149. Morse HG, Hays T, Patterson D, Robinson A (1982): Giemsa-11 technique: Applications in the chromosomal characterization of hematological specimens. Hum Genet. 61:141-144. 150. Robinson A (1982):a. Trisomy X female (47,XXX),pp 552-553; b. 46,XX male, pp 555-557; c. 47,XXY Male, Klinefelter syndrome, pp 557-558; d. 48,XXXY, Klinefelter variant, pp 559-560; e. 49,XXXXY syndrome, pp 560-562; f. 48,XXYY and 49,XXXYY Klinefelter variants, pp 562-564. In Myrianthopoulos NC (ed): “Handbook of Clinical Neurology, Vol. 43, Neurogenetic Directory, Part TI.” Amsterdam: Elsevier. 151. Robinson A, Bender B, Borelli J, Puck M, Salbenblatt J, Webber ML (1982):Sex chromosomal abnormalities (SCA):A prospective and longitudinal study of newborns identified in an unbiased manner. In Stewart DA (ed): “Children With Sex Chromosome Aneuploidy: Follow-up Studies. New York Alan R. Liss, Inc., for the National Foundation-March of Dimes. BD:OAS 18(4):7-39. 152. Bender BG, Puck MH, Salbenblatt JA, Robinson A (1983): Hemispheric organisation in 47,XXY boys. Lancet 1:132. 153. Bender B, Fry E, Pennington B, Puck M, Salbenblatt J, Robinson A (1983): Speech and language development of 41 children with sex chromosome anomalies. Pediatrics 71:262-267. 154. Robinson A, Bender B, Borelli J , Puck M, Salbenblatt J (1983): Sex chromosomal anomalies: Prospective studies in children. Behav Genet 13:321-329. 155. Puck MH. Bender BG. Borelli JB. Salbenhlatt JA. Robinson A (1983): Parents’ adaptation to early diagnosis of sex’chromosome anomalies. Am J Med Genet 16:l-79. 156. Morse HG, Odom LF, Tubergen D, Hays T, Blake M. Robinson A (1983):Prognosis in acute lymphoblastic leukemia of childhood as determined by cytogenetic studies at diagnosis. Med Pediatr OnC O ~11.310-318. 157. Bayless-Underwood L, Cho S, Ward B, Robinson A (1983): Two cases of satellited Yq chromosome. Clin Genet 24:359- 364. 158. Iselius L. (24 authors including A Robinson) (1983):The llq;22q translocation: A collaborative study of 20 new cases and analysis of 110 families. Hum Genet 64:343- 355. 159. Robinson A (1983):Foreword. In HagermanRJ, McBogg PM (eds): “Fragile X Syndrome: Diagnosis, Biochemistry, and Intervention.” Dillon, Colo.: Spectra Publishing Co. 160. Robinson A (1984):Review of genetic concepts. Ch 14,pp 131-139; Genetic consequences of radiation exposure. Ch 15, pp 141-145. In Hendee WR ied): “Health Effects of Low-Level Radiation.” Norwalk, Conn.: Appleton-Century-Crofts. 161. Bender B, Puck M, Salbenblatt J , Robinson A (1984): Cognitive development of unselected girls with complete and partial X monosomy. Pediatrics 73:175-182. 162. Bender BG, Puck MH, Salbenblatt JA, Robinson A (1984): The development of four unselected 47,XYY boys. Clin Genet 25:435-445. 163. Robinson A (1984): Principles of heredity and genetics (Revision). In “Encyclopaedia Britannica.” Chicago: Encyclopaedia Britannica, Inc. 164. Robinson A (1984):Birth defects and congenital disorders (Revi-
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sion). In “Encyclopaedia Britannica.” Chicago: Encyclopaedia Britannica, Inc. 165. Robinson A, Goodman SI, O’Brien D (1984): Genetic and chromosomal disorders, including inborn errors of metabolism. In Kempe CH, Silver HK, O’Brien D (eds):“Current Pediatric Diagnosis and ‘keatment,” 8th edition. Los Altos, Calif.: Lange Medical Publications, ch 33, pp 992-1030. 166. Robinson A (1984): Book review: Issues and Reviews in Teratology, Vol. I, edited by H. Kalter. Am J Hum Genet 36:721-722. 167. Borelli JB, Bender BG, Puck MH, Salbenblatt, JA, Robinson A (1984):The meaning of early knowledge of a child’s infertility in families with 47,XXY and 45,X children. Child Psychiatry Hum Dev 14:215-222. 168. Salbenblatt JA, Bender BG, Puck MH, Robinson A, Faiman C, Winter JSD (1985): Pituitary-gonadal function in Klinefelter syndrome before and during puberty. Pediatr Res 19232-86. 169. Robinson A, Bender B, Borelli J, Puck M, Salbenblatt J (1985): Sex chromosomal anomalies: Prospective studies in children. In Chess S, Thomas A (eds): “Annual Progress in Child Psychiatry and Child Development, 1984. New York: BrunnerMazel, pp 133-142. (Republished from Behav Genet 13:321-329,1983, as an outstanding contribution to the understanding and treatment of the normal and disturbed child.) 170. Robinson A, Henry GP (1985): Prenatal diagnosis by amniocentesis. Annu Rev Med 36:13-26. 171. Robinson A, Bender BG, PuckMH, SalbenblattJA (1985):Growth and development of children with a 47,XYY karyotype. In “The Y Chromosome, Part B: Clinical Aspects of Y Chromosome Abnormalities.” Progress and Topics in Cytogenetics, Vol. 6B. Sandberg AA (ed):New York: Alan R. Liss, Inc., pp 265-275. 172. Robinson A (1986): Genetics and heredity. In “Encyclopaedia Britannica.” Chicago: Encyclopaedia Britannica, Inc. 173. Bradley DM, Patterson L), Robinson A (1986): Somatic Cell genetic studies on a family with Down syndrome due to an unusual translocation (21q22 2lqter). Tris 21 1:41-52. 174. Bender BG, Puck MH, Salbenblatt JA, Robinson A (1986): Cognitive development of children with sex chromosome abnormalities. In Smith S (ed): “Genetics and Learning Disabilities.” San Diego: College Hill Press, pp 175-201. 175. Robinson A, Bender BG, Borelli JB, Puck MH, Salbenblatt JA, Winter JSD (1986): Sex chromosomal aneuploidy: Prospective and longitudinal studies. In: “Prospective Studies on Children With Sex Chromosome Aneuploidy.” Ratcliffe SG, Paul N p (eds): New York: Alan R. Liss, Inc., for the National FoundationMarch of Dimes. BD:OAS 22(3):23-71. 176. Bender BG, Puck MH, Salbenblatt JA, Robinson A (1986): Dyslexia in 47,XXY boys identified at birth. Behav Genet 16:343-354. 177. Robinson A (1986):Book review: Fragile Sites on Human Chromosomes, by G.R. Sutherland and F. Hecht. Q Rev Biol 61:263. 178. Salbenblatt JA, Meyers DC, Bender BG, Linden MG, Robinson A (1987): Gross and fine motor development in 47,XXY and 47,XYY males. Pediatrics 80:240-244. 179. Morse HG, Odom LF, Castro R, Hays T, Blake M, Vannais D,
180.
181. 182. 183.
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Robinson A (1987): Methodology of premature chromosome condensation and its potential for relapse prediction in acute leukemia of children and adolescents. Cancer Genet Cytogenet 27:51-61. Morse HG, Odom LF, Castro R, Hays T, Blake M, Vannais D, Robinson A (1987): Premature chromosome condensation as a predictive indicator of relapse in children and adolescents with acute leukemia: Initial observations. Cancer Genet Cytogenet 27:63-72. Bender BG, Linden MG, Robinson A (1987): Environment and developmental risk in children with sex chromosome abnormalities. J Am Acad Child Adolesc Psychiatry 26499-503. Robinson A (1987): Genetics and the future of medicine. Somatic Cell Mol Genet 13(4):485-489. Smith ACM, Spuyler K, Williams TM, McConnell T, Sujansky E, Robinson A (1987): Genetic risk for recombinant 8 syndrome and the transmission rate of balanced inversion 8 in the Hispanic population of the southwestern United States. Am J Hum Genet 41:1083-1103. Wheeler M, PeakmanD, Robinson A, Henry G (1988):45,X/46,XY mosaicism: Contrast of prenatal and postnatal diagnosis. Am J Med Genet 29565-571. Robinson A (1988):Introduction: Genetics and the health professional. In “Genetic Applications: A Health Perspective.” Lawrence, Kansas: Learner Managed Designs, pp 1-3. Linden MG, Bender BG, Harmon FLJ, Mrazek DA, Robinson A (1988):47,XXX: What is the prognosis? Pediatrics 82619-630. Ward BE, Hayden MW, Robinson A (1988): Isochromosome 12p mosaicism (Pallister-Killian syndrome): Newborn diagnosis by direct bone marrow analysis. Am J Med Genet 31:835-839. Bender BG, Linden MG, Robinson A (1989): Verbal and spatial processing eficiency in 32 children with sex chromosome abnormalities. Pediatr Res 25577-579. Robinson A (in press): Demography and prevalence ofl’urner’s. In Rosenfeld R, Grumbach M (eds): ‘‘Turner Syndrome.” New York: Marcel Dekker, Inc. Bender BG, Linden M, Robinson A (in press): SCA In search of developmental patterns. In Berch D, Bender B (eds): “Sex Chromosome Abnormalities and Behavior: Psychological Studies.” Washington, D.C.: Westview Press and American Association for the Advancement of Science. Salbenblatt JA, Meyers DC, Bender BG, Linden MG, Robinson A (in press): Gross and fine motor development in 45,X and 47,XXX females. Pediatrics. Robinson A, Bender BG, Linden MG (in press): Decisions following the intrauterine diagnosis of sex chromosome aneuploidy. Am J Med Genet. Robinson A (in press): Book review: Proceed with Caution: Predicting Genetic Risks in the Recombinant DNA Era, by Neil A. Holtzman. The Pharos. Robinson A, Bender BG, Linden MG, Salbenblatt JA (in press): Sex chromosome aneuploidy: The Denver prospective study. Birth Defects.
