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Special populations
ORIGINAL ARTICLE
Association between blood pressure and risk of cardiovascular hospital admissions among people with type 2 diabetes Dahai Yu, David Simmons ▸ Additional material is published online only. To view please visit the journal online (http://dx.doi.org/10.1136/ heartjnl-2013-304799). Institute of Metabolic Science, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK Correspondence to Professor David Simmons, Institute of Metabolic Science, Cambridge University Hospitals NHS Foundation Trust, Cambridge CB2 0QQ, UK; [email protected] Received 8 August 2013 Revised 31 March 2014 Accepted 13 April 2014 Published Online First 16 May 2014
ABSTRACT Objective To investigate the association between systolic and diastolic blood pressure (BP) and risk of hospitalisation among patients with type 2 diabetes. Methods 4704 patients with type 2 diabetes from 18 general practices in Cambridgeshire were included. BP was assessed in 2008–2009. The primary outcome was cardiovascular hospital admissions in 2009–2011. Adjusted relative risks for each BP measurement group were estimated using Cox models. Further dose–response relationships between BP and risks were explored using restricted cubic spline models. Results Over a median follow-up of 2 years, we recorded 5322 hospital admissions. There was a nonlinear relationship between systolic (SBP) and diastolic (DBP) BP and the risk of cardiovascular hospitalisation (both p
Special populations
ORIGINAL ARTICLE
Association between blood pressure and risk of cardiovascular hospital admissions among people with type 2 diabetes Dahai Yu, David Simmons ▸ Additional material is published online only. To view please visit the journal online (http://dx.doi.org/10.1136/ heartjnl-2013-304799). Institute of Metabolic Science, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK Correspondence to Professor David Simmons, Institute of Metabolic Science, Cambridge University Hospitals NHS Foundation Trust, Cambridge CB2 0QQ, UK; [email protected] Received 8 August 2013 Revised 31 March 2014 Accepted 13 April 2014 Published Online First 16 May 2014
ABSTRACT Objective To investigate the association between systolic and diastolic blood pressure (BP) and risk of hospitalisation among patients with type 2 diabetes. Methods 4704 patients with type 2 diabetes from 18 general practices in Cambridgeshire were included. BP was assessed in 2008–2009. The primary outcome was cardiovascular hospital admissions in 2009–2011. Adjusted relative risks for each BP measurement group were estimated using Cox models. Further dose–response relationships between BP and risks were explored using restricted cubic spline models. Results Over a median follow-up of 2 years, we recorded 5322 hospital admissions. There was a nonlinear relationship between systolic (SBP) and diastolic (DBP) BP and the risk of cardiovascular hospitalisation (both p
