Contrast-induced Nephropathy
Association Between Contrast Media Volume–Glomerular Filtration Rate Ratio and Contrast-Induced Acute Kidney Injury After Primary Percutaneous Coronary Intervention
Angiology 2015, Vol. 66(6) 519-524 ª The Author(s) 2014 Reprints and permission: sagepub.com/journalsPermissions.nav DOI: 10.1177/0003319714542277 ang.sagepub.com
Omer Celik, MD1, Derya Ozturk, MD1, Fatih Akin, MD2, Burak Ayca, MD3, Ahmet Arif Yalcın, MD1, Mehmet Erturk, MD1, Ismail Bıyık, MD1, Ahmet Ayaz, MD1, Ibrahim Faruk Akturk, MD1, Asım Enhos, MD1, and Serkan Aslan, MD1
Abstract We hypothesized that contrast media volume–estimated glomerular filtration rate (CV–e-GFR) ratio may be a predictor of contrast media-induced acute kidney injury (CI-AKI). We investigated the associations between CV–e-GFR ratio and CI-AKI in 597 patients undergoing primary percutaneous coronary intervention (pPCI). An absolute 0.3 mg/dL increase in serum creatinine compared with baseline levels within 48 hours after the procedure was considered as CI-AKI; 78 (13.1%) of the 597 patients experienced CI-AKI. The amount of contrast during procedure was higher in the CI-AKI group than in those without CI-AKI (153 vs 135 mL, P ¼ .003). The CV–e-GFR ratio was significantly higher in patients with CI-AKI than without (2.3 vs 1.5, P < .001). In multivariate analysis, independent predictors of CI-AKI were low left ventricular ejection fraction (P ¼ .018, odds ratio [OR] ¼ 0.966), e-GFR 2 (P < .001, OR ¼ 5.917). In conclusion, CV–e-GFR ratio is significantly associated with CI-AKI after pPCI. Keywords contrast-induced acute kidney injury, contrast media volume–estimated glomerular filtration ratio, primary percutaneous coronary intervention
Introduction Contrast media-induced acute kidney injury (CI-AKI) is a relatively common complication of invasive cardiovascular procedures, especially after primary percutaneous coronary intervention (pPCI).1 Although the incidence of AKI is
Association Between Contrast Media Volume–Glomerular Filtration Rate Ratio and Contrast-Induced Acute Kidney Injury After Primary Percutaneous Coronary Intervention
Angiology 2015, Vol. 66(6) 519-524 ª The Author(s) 2014 Reprints and permission: sagepub.com/journalsPermissions.nav DOI: 10.1177/0003319714542277 ang.sagepub.com
Omer Celik, MD1, Derya Ozturk, MD1, Fatih Akin, MD2, Burak Ayca, MD3, Ahmet Arif Yalcın, MD1, Mehmet Erturk, MD1, Ismail Bıyık, MD1, Ahmet Ayaz, MD1, Ibrahim Faruk Akturk, MD1, Asım Enhos, MD1, and Serkan Aslan, MD1
Abstract We hypothesized that contrast media volume–estimated glomerular filtration rate (CV–e-GFR) ratio may be a predictor of contrast media-induced acute kidney injury (CI-AKI). We investigated the associations between CV–e-GFR ratio and CI-AKI in 597 patients undergoing primary percutaneous coronary intervention (pPCI). An absolute 0.3 mg/dL increase in serum creatinine compared with baseline levels within 48 hours after the procedure was considered as CI-AKI; 78 (13.1%) of the 597 patients experienced CI-AKI. The amount of contrast during procedure was higher in the CI-AKI group than in those without CI-AKI (153 vs 135 mL, P ¼ .003). The CV–e-GFR ratio was significantly higher in patients with CI-AKI than without (2.3 vs 1.5, P < .001). In multivariate analysis, independent predictors of CI-AKI were low left ventricular ejection fraction (P ¼ .018, odds ratio [OR] ¼ 0.966), e-GFR 2 (P < .001, OR ¼ 5.917). In conclusion, CV–e-GFR ratio is significantly associated with CI-AKI after pPCI. Keywords contrast-induced acute kidney injury, contrast media volume–estimated glomerular filtration ratio, primary percutaneous coronary intervention
Introduction Contrast media-induced acute kidney injury (CI-AKI) is a relatively common complication of invasive cardiovascular procedures, especially after primary percutaneous coronary intervention (pPCI).1 Although the incidence of AKI is
