Open Access
Research
Association between secondhand smoke and obesity and glucose abnormalities: data from the National Health and Nutrition Examination Survey (NHANES 1999–2010) Dulcie Kermah,1 Magda Shaheen,1 Deyu Pan,1 Theodore C Friedman2 To cite: Kermah D, Shaheen M, Pan D, et al. Association between secondhand smoke and obesity and glucose abnormalities: data from the National Health and Nutrition Examination Survey (NHANES 1999–2010). BMJ Open Diabetes Research and Care 2017;5:e000324. doi:10.1136/bmjdrc-2016000324
ABSTRACT Objective: The objective of this study is to investigate
1
the relationship between cotinine level-confirmed secondhand smoke (SHS) exposure and glycemic parameters and obesity. Research design and methods: We examined a cohort of 6472 adults from the National Health and Nutrition Examination Surveys, 1999–2010. Serum cotinine levels and self-reported data on smoking were used to determine smoking status. The outcome variables were body mass index (BMI) and glycemic status (HbA1c), Homeostasis Model Assessment of Insulin Resistance (HOMA-IR), and fasting plasma glucose (FPG). Descriptive, bivariate, and multivariate analyses were conducted. Results: Using cotinine level-confirmed smoking status, 1794 (27.4%) of the sample were current smokers, 1681 (25.0%) were former smokers, 1158 (17.8%) were secondhand smokers, and 1839 (29.8%) were non-smokers. In a generalized linear model after controlling for potential confounding variables, secondhand smokers had higher adjusted levels of HOMA-IR, FPG, and BMI compared with non-smokers ( p
Research
Association between secondhand smoke and obesity and glucose abnormalities: data from the National Health and Nutrition Examination Survey (NHANES 1999–2010) Dulcie Kermah,1 Magda Shaheen,1 Deyu Pan,1 Theodore C Friedman2 To cite: Kermah D, Shaheen M, Pan D, et al. Association between secondhand smoke and obesity and glucose abnormalities: data from the National Health and Nutrition Examination Survey (NHANES 1999–2010). BMJ Open Diabetes Research and Care 2017;5:e000324. doi:10.1136/bmjdrc-2016000324
ABSTRACT Objective: The objective of this study is to investigate
1
the relationship between cotinine level-confirmed secondhand smoke (SHS) exposure and glycemic parameters and obesity. Research design and methods: We examined a cohort of 6472 adults from the National Health and Nutrition Examination Surveys, 1999–2010. Serum cotinine levels and self-reported data on smoking were used to determine smoking status. The outcome variables were body mass index (BMI) and glycemic status (HbA1c), Homeostasis Model Assessment of Insulin Resistance (HOMA-IR), and fasting plasma glucose (FPG). Descriptive, bivariate, and multivariate analyses were conducted. Results: Using cotinine level-confirmed smoking status, 1794 (27.4%) of the sample were current smokers, 1681 (25.0%) were former smokers, 1158 (17.8%) were secondhand smokers, and 1839 (29.8%) were non-smokers. In a generalized linear model after controlling for potential confounding variables, secondhand smokers had higher adjusted levels of HOMA-IR, FPG, and BMI compared with non-smokers ( p
