The New England Journal of Medicine Downloaded from nejm.org at RUTGERS UNIV ALEXANDER LIBRARY on July 2, 2014. For personal use only. No other uses without permission. Copyright © 1991 Massachusetts Medical Society. All rights reserved.

The New England Journal of Medicine Downloaded from nejm.org at RUTGERS UNIV ALEXANDER LIBRARY on July 2, 2014. For personal use only. No other uses without permission. Copyright © 1991 Massachusetts Medical Society. All rights reserved.

The New England Journal of Medicine Downloaded from nejm.org at RUTGERS UNIV ALEXANDER LIBRARY on July 2, 2014. For personal use only. No other uses without permission. Copyright © 1991 Massachusetts Medical Society. All rights reserved.

The New England Journal of Medicine Downloaded from nejm.org at RUTGERS UNIV ALEXANDER LIBRARY on July 2, 2014. For personal use only. No other uses without permission. Copyright © 1991 Massachusetts Medical Society. All rights reserved.

The New England Journal of Medicine Downloaded from nejm.org at RUTGERS UNIV ALEXANDER LIBRARY on July 2, 2014. For personal use only. No other uses without permission. Copyright © 1991 Massachusetts Medical Society. All rights reserved.

The New England Journal of Medicine Downloaded from nejm.org at RUTGERS UNIV ALEXANDER LIBRARY on July 2, 2014. For personal use only. No other uses without permission. Copyright © 1991 Massachusetts Medical Society. All rights reserved.

Association between tumor necrosis factor-alpha and disease progression in patients with multiple sclerosis.

Cachectin, or tumor necrosis factor-alpha (TNF-alpha), is a principal mediator of the inflammatory response and may be important in the pathogenesis a...
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