CLINICAL RESEARCH e-ISSN 1643-3750 © Med Sci Monit, 2015; 21: 3121-3128 DOI: 10.12659/MSM.895866

Association of Serum Chemerin Levels with Acute Ischemic Stroke and Carotid Artery Atherosclerosis in a Chinese Population

Received: 2015.09.03 Accepted: 2015.09.28 Published: 2015.10.16

Authors’ ABCDEF Contribution: Dandan Zhao Study Design  A ABCDEFG Guorong Bi Data Collection  B AE Juan Feng Statistical Analysis  C Data Interpretation  EF D Rui Huang Manuscript Preparation  E EF Xinyue Chen Literature Search  F Funds Collection  G



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Department of Neurology, Shengjing Hospital Affiliated to China Medical University, Shenyang, Liaoning, P.R. China

Guorong Bi, e-mail: [email protected] Departmental sources

The aim of this study was to examine the association between serum level of chemerin with AIS and carotid artery atherosclerosis, and to investigate the level of chemerin as a potential novel cerebrovascular risk factor. We compared the serum chemerin levels and cerebrovascular parameters between 70 AIS patients and 70 nonAIS subjects in a Chinese population. Enzyme-linked immunosorbent assay (ELISA) was used to measure the levels of serum chemerin. The state of carotid artery plaques in the AIS group was detected by color Doppler ultrasound. We used SPSS software for statistical analysis. Compared with the non-AIS group, serum level of chemerin in the AIS group increased significantly (p