Wang et al. Cardiovasc Diabetol (2016) 15:118 DOI 10.1186/s12933-016-0445-y
ORIGINAL INVESTIGATION
Cardiovascular Diabetology Open Access
Associations between blood glucose level and outcomes of adult in‑hospital cardiac arrest: a retrospective cohort study Chih‑Hung Wang1,2, Chien‑Hua Huang1, Wei‑Tien Chang1, Min‑Shan Tsai1, Ping‑Hsun Yu3, Yen‑Wen Wu4,5,6 and Wen‑Jone Chen1,7*
Abstract Background: We intended to analyse the associations between blood glucose (BG) level and clinical outcomes of in-hospital cardiac arrest (IHCA). Methods: We conducted a retrospective observational study in a single medical centre and evaluated patients who experienced IHCA between 2006 and 2014. We used multivariable logistic regression analysis to study associations between independent variables and outcomes. We calculated the mean BG level for each patient by averaging the maximum and minimum BG levels in the first 24 h after arrest, and we used mean BG level for our final analysis. Results: We included a total of 402 patients. Of these, 157 patients (39.1 %) had diabetes mellitus (DM). The aver‑ age mean BG level was 209.9 mg/dL (11.7 mmol/L). For DM patients, a mean BG level between 183 and 307 mg/dL (10.2–17.1 mmol/L) was significantly associated with favourable neurological outcome (odds ratio [OR] 2.71, 95 % confidence interval [CI] 1.18–6.20; p value = 0.02); a mean BG level between 147 and 317 mg/dL (8.2–17.6 mmol/L) was significantly associated with survival to hospital discharge (OR 2.38, 95 % CI 1.26–4.53; p value = 0.008). For non-DM patients, a mean BG level between 143 and 268 mg/dL (7.9–14.9 mmol/L) was significantly associated with survival to hospital discharge (OR 2.93, 95 % CI 1.62–5.40; p value
ORIGINAL INVESTIGATION
Cardiovascular Diabetology Open Access
Associations between blood glucose level and outcomes of adult in‑hospital cardiac arrest: a retrospective cohort study Chih‑Hung Wang1,2, Chien‑Hua Huang1, Wei‑Tien Chang1, Min‑Shan Tsai1, Ping‑Hsun Yu3, Yen‑Wen Wu4,5,6 and Wen‑Jone Chen1,7*
Abstract Background: We intended to analyse the associations between blood glucose (BG) level and clinical outcomes of in-hospital cardiac arrest (IHCA). Methods: We conducted a retrospective observational study in a single medical centre and evaluated patients who experienced IHCA between 2006 and 2014. We used multivariable logistic regression analysis to study associations between independent variables and outcomes. We calculated the mean BG level for each patient by averaging the maximum and minimum BG levels in the first 24 h after arrest, and we used mean BG level for our final analysis. Results: We included a total of 402 patients. Of these, 157 patients (39.1 %) had diabetes mellitus (DM). The aver‑ age mean BG level was 209.9 mg/dL (11.7 mmol/L). For DM patients, a mean BG level between 183 and 307 mg/dL (10.2–17.1 mmol/L) was significantly associated with favourable neurological outcome (odds ratio [OR] 2.71, 95 % confidence interval [CI] 1.18–6.20; p value = 0.02); a mean BG level between 147 and 317 mg/dL (8.2–17.6 mmol/L) was significantly associated with survival to hospital discharge (OR 2.38, 95 % CI 1.26–4.53; p value = 0.008). For non-DM patients, a mean BG level between 143 and 268 mg/dL (7.9–14.9 mmol/L) was significantly associated with survival to hospital discharge (OR 2.93, 95 % CI 1.62–5.40; p value
