Lettres à la rédaction / Médecine et maladies infectieuses 44 (2014) 79–82
ciprofloxaxine. La durée du traitement n’est pas différent des arthrites dues à des germes pyogènes habituels. 4. Conclusion
81 ∗ Auteur
correspondant. Adresse e-mail : [email protected] (E. Ricard) Rec¸u le 25 novembre 2013 Rec¸u sous la forme révisée le 2 d´ecembre 2013
K. kingae est exceptionnellement responsable d’infections ostéoarticulaires chez l’adulte alors qu’il constitue le germe le plus souvent impliqué des infections ostéoarticulaires du petit enfant. Le tableau clinique est généralement pauvre, ce qui doit alerter le clinicien confronté à une arthrite paucisymptomatique. Ceci lui permettra de travailler de concert avec le microbiologiste, de fac¸on à mettre toutes les techniques en œuvre pour isoler le germe et le traiter au mieux le patient.
http://dx.doi.org/10.1016/j.medmal.2013.12.005
Déclaration d’intérêts
Hépatite A biphasique avec cholestase et purpura thrombopénique graves chez un patient infecté par le VIH
Accepté le 31 d´ecembre 2013 Disponible sur Internet le 18 f´evrier 2014
Biphasic hepatitis A with severe cholestasis and thrombocytopenic purpura in an HIV-1-infected male patient
Les auteurs déclarent ne pas avoir de conflits d’intérêts en relation avec cet article. Keywords: HIV infection; HAV infection; Thrombocytopenic purpura
Références
Mots clés : Infection VIH ; Hépatite A ; Purpura thrombocytopénique
[1] Lewis DA, Settas L. Kingella kingae causing septic arthritis in Felty’s syndrome. Postgrad Med J 1983;59(694):525–6. [2] Salminen I, von Essen R, Koota K, Nissinen A. A pitfall in purulent arthritis brought out in Kingella kingae infection of the knee. Ann Rheum Dis 1984;43(4):656–7. [3] Estève V, Porcheret H, Clerc D, Dorfmann H, Le Pennec MP. Septic arthritis due to Kingella kingae in an adult. Joint Bone Spine 2001;68(1):85–6. [4] Vincent J, Podewell C, Franklin GW, Korn JH. Septic arthritis due to Kingella (Moraxella) kingii: case report and review of the literature. J Rheumatol 1981;8(3):501–3. [5] Elyès B, Mehdi G, Kamel BHS, Hela Z, Imen BS. Kingella kingae septic arthritis with endocarditis in an adult. Joint Bone Spine 2006;73(4):472–3. [6] Rosenbaum J, Lieberman DH, Katz WA. Moraxella infectious arthritis: first report in an adult. Ann Rheum Dis 1980;39(2): 184–5. [7] Meis JF, Sauerwein RW, Gyssens IC, Horrevorts AM, van Kampen A. Kingella kingae intervertebral diskitis in an adult. Clin Infect Dis Off Publ Infect Dis Soc Am 1992;15(3):530–2. [8] Ducoulombier V, Dehecq E, Luraschi H, Prudhomme C, Bessard D, Houvenagel E. Kingella kingae spondylodiscitis in an adult. Medecine Mal Infect 2011;41(2):110–2. [9] Le Bars H, Lamini N, Brunet JF, Duval H, Samjee I, Minet J. Sacroiliitis due to Kingella kingae in an adult: updates on this pathogen. Ann Biol Clin (Paris) 2010;68(3):341–5. [10] Wilmes D, Omoumi P, Squifflet J, Cornu O, Rodriguez-Villalobos H, Yombi JC. Osteomyelitis pubis caused by Kingella kingae in an adult patient: report of the first case. BMC Infect Dis 2012;12:236.
HAV can occasionally cause a relapsing and prolonged cholestatic disease [1]. The initial episode of biphasic viral hepatitis A usually lasts 3 to 5 weeks and is followed by a 4 to 5 week period of remission with normal liver biochemistry. The second episode may mimic the initial episode. The full course of the illness ranges from 16 to 40 weeks, and anti-HAV IgM persists throughout [1]. Viral and host factors involved in the pathogenesis of atypical acute hepatitis A have rarely been investigated [2]. We report a case of biphasic hepatitis A, with severe cholestasis and thrombocytopenic purpura during the second episode, in an HIV-1-infected male patient. A 44-year-old male patient who had sex with men was diagnosed simultaneously with primary HIV infection and acute hepatitis B in 2000. He recovered from hepatitis B and developed antibodies to hepatitis B surface antigen. Highly active antiretroviral treatment (zidovudine, lamivudine, and lopinavir) was initiated in 2004. His history was otherwise unremarkable. In September 2007, he presented with fatigue, jaundice, and loss of appetite. The alanine aminotransferase (ALT) level was 2,326 IU/L (normal < 60 IU/L), the gamma-glutamyl transferase 458 IU/L (normal < 45 IU/L), the alkaline phosphatase 188 IU/L (normal
ciprofloxaxine. La durée du traitement n’est pas différent des arthrites dues à des germes pyogènes habituels. 4. Conclusion
81 ∗ Auteur
correspondant. Adresse e-mail : [email protected] (E. Ricard) Rec¸u le 25 novembre 2013 Rec¸u sous la forme révisée le 2 d´ecembre 2013
K. kingae est exceptionnellement responsable d’infections ostéoarticulaires chez l’adulte alors qu’il constitue le germe le plus souvent impliqué des infections ostéoarticulaires du petit enfant. Le tableau clinique est généralement pauvre, ce qui doit alerter le clinicien confronté à une arthrite paucisymptomatique. Ceci lui permettra de travailler de concert avec le microbiologiste, de fac¸on à mettre toutes les techniques en œuvre pour isoler le germe et le traiter au mieux le patient.
http://dx.doi.org/10.1016/j.medmal.2013.12.005
Déclaration d’intérêts
Hépatite A biphasique avec cholestase et purpura thrombopénique graves chez un patient infecté par le VIH
Accepté le 31 d´ecembre 2013 Disponible sur Internet le 18 f´evrier 2014
Biphasic hepatitis A with severe cholestasis and thrombocytopenic purpura in an HIV-1-infected male patient
Les auteurs déclarent ne pas avoir de conflits d’intérêts en relation avec cet article. Keywords: HIV infection; HAV infection; Thrombocytopenic purpura
Références
Mots clés : Infection VIH ; Hépatite A ; Purpura thrombocytopénique
[1] Lewis DA, Settas L. Kingella kingae causing septic arthritis in Felty’s syndrome. Postgrad Med J 1983;59(694):525–6. [2] Salminen I, von Essen R, Koota K, Nissinen A. A pitfall in purulent arthritis brought out in Kingella kingae infection of the knee. Ann Rheum Dis 1984;43(4):656–7. [3] Estève V, Porcheret H, Clerc D, Dorfmann H, Le Pennec MP. Septic arthritis due to Kingella kingae in an adult. Joint Bone Spine 2001;68(1):85–6. [4] Vincent J, Podewell C, Franklin GW, Korn JH. Septic arthritis due to Kingella (Moraxella) kingii: case report and review of the literature. J Rheumatol 1981;8(3):501–3. [5] Elyès B, Mehdi G, Kamel BHS, Hela Z, Imen BS. Kingella kingae septic arthritis with endocarditis in an adult. Joint Bone Spine 2006;73(4):472–3. [6] Rosenbaum J, Lieberman DH, Katz WA. Moraxella infectious arthritis: first report in an adult. Ann Rheum Dis 1980;39(2): 184–5. [7] Meis JF, Sauerwein RW, Gyssens IC, Horrevorts AM, van Kampen A. Kingella kingae intervertebral diskitis in an adult. Clin Infect Dis Off Publ Infect Dis Soc Am 1992;15(3):530–2. [8] Ducoulombier V, Dehecq E, Luraschi H, Prudhomme C, Bessard D, Houvenagel E. Kingella kingae spondylodiscitis in an adult. Medecine Mal Infect 2011;41(2):110–2. [9] Le Bars H, Lamini N, Brunet JF, Duval H, Samjee I, Minet J. Sacroiliitis due to Kingella kingae in an adult: updates on this pathogen. Ann Biol Clin (Paris) 2010;68(3):341–5. [10] Wilmes D, Omoumi P, Squifflet J, Cornu O, Rodriguez-Villalobos H, Yombi JC. Osteomyelitis pubis caused by Kingella kingae in an adult patient: report of the first case. BMC Infect Dis 2012;12:236.
HAV can occasionally cause a relapsing and prolonged cholestatic disease [1]. The initial episode of biphasic viral hepatitis A usually lasts 3 to 5 weeks and is followed by a 4 to 5 week period of remission with normal liver biochemistry. The second episode may mimic the initial episode. The full course of the illness ranges from 16 to 40 weeks, and anti-HAV IgM persists throughout [1]. Viral and host factors involved in the pathogenesis of atypical acute hepatitis A have rarely been investigated [2]. We report a case of biphasic hepatitis A, with severe cholestasis and thrombocytopenic purpura during the second episode, in an HIV-1-infected male patient. A 44-year-old male patient who had sex with men was diagnosed simultaneously with primary HIV infection and acute hepatitis B in 2000. He recovered from hepatitis B and developed antibodies to hepatitis B surface antigen. Highly active antiretroviral treatment (zidovudine, lamivudine, and lopinavir) was initiated in 2004. His history was otherwise unremarkable. In September 2007, he presented with fatigue, jaundice, and loss of appetite. The alanine aminotransferase (ALT) level was 2,326 IU/L (normal < 60 IU/L), the gamma-glutamyl transferase 458 IU/L (normal < 45 IU/L), the alkaline phosphatase 188 IU/L (normal
