Original Article
Access this article online Website: www.ijciis.org DOI: 10.4103/2229-5151.147518 Quick Response Code:
Broadening of the red blood cell distribution width is associated with increased severity of illness in patients with sepsis Nader A Mahmood1,2, Jacob Mathew1, Balwinder Kang1, Vincent A DeBari2, Muhammad Anees Khan1,2
ABSTRACT
Pulmonary Division, St. Joseph’s Regional Medical Center, Paterson, 2 Seton Hall University, School of Health and Medical Sciences, South Orange, NJ, USA
1
Background: Sepsis is a pro‑inflammatory state caused by systemic infection. As sepsis progresses, multiple organ systems become affected with subsequent increase in mortality. Elevated red cell distribution width (RDW) has been seen with changes of other inflammatory markers and thus could potentially serve as a means of assessing sepsis severity. In this study, we examine the association of RDW with APACHE II score and in‑hospital mortality. Meterials and Methods: We conducted a retrospective study involving a cohort of patients with sepsis. The study period spanned 2 years with a cohort of 349 patients. Data were collected to determine if RDW is associated with APACHE II scores and in‑hospital mortality in this cohort.
Address for correspondence: Dr. Vincent A DeBari, Seton Hall University, School of Health and Medical Sciences, 400 South Orange Ave., South Orange, NJ - 07079, USA. E‑mail: [email protected]
Results: RDW correlated weakly (rs = 0.27), but significantly (P
Access this article online Website: www.ijciis.org DOI: 10.4103/2229-5151.147518 Quick Response Code:
Broadening of the red blood cell distribution width is associated with increased severity of illness in patients with sepsis Nader A Mahmood1,2, Jacob Mathew1, Balwinder Kang1, Vincent A DeBari2, Muhammad Anees Khan1,2
ABSTRACT
Pulmonary Division, St. Joseph’s Regional Medical Center, Paterson, 2 Seton Hall University, School of Health and Medical Sciences, South Orange, NJ, USA
1
Background: Sepsis is a pro‑inflammatory state caused by systemic infection. As sepsis progresses, multiple organ systems become affected with subsequent increase in mortality. Elevated red cell distribution width (RDW) has been seen with changes of other inflammatory markers and thus could potentially serve as a means of assessing sepsis severity. In this study, we examine the association of RDW with APACHE II score and in‑hospital mortality. Meterials and Methods: We conducted a retrospective study involving a cohort of patients with sepsis. The study period spanned 2 years with a cohort of 349 patients. Data were collected to determine if RDW is associated with APACHE II scores and in‑hospital mortality in this cohort.
Address for correspondence: Dr. Vincent A DeBari, Seton Hall University, School of Health and Medical Sciences, 400 South Orange Ave., South Orange, NJ - 07079, USA. E‑mail: [email protected]
Results: RDW correlated weakly (rs = 0.27), but significantly (P
