Support Care Cancer DOI 10.1007/s00520-014-2265-5
ORIGINAL ARTICLE
Cancer-related fatigue in patients before and after radical prostatectomy. Results of a prospective multi-centre study Norbert Köhler & Lutz Gansera & Sigrun Holze & Michael Friedrich & Udo Rebmann & Jens-Uwe Stolzenburg & Michael C. Truss & Dirk Fahlenkamp & Hans-Jörg Scholz & Elmar Brähler
Received: 2 October 2013 / Accepted: 22 April 2014 # Springer-Verlag Berlin Heidelberg 2014
Abstract Purpose A multi-centre, longitudinal study was conducted to assess the prevalence of fatigue amongst men with localized prostate cancer, to describe several dimensions of fatigue and to explore the predictability of fatigue by psychological distress and physical function. Methods The prevalence of fatigue was evaluated using the Multidimensional Fatigue Inventory in 329 prostate cancer patients before, 3, 6 and 12 months after surgery. Psychological distress was assessed using the Hospital Anxiety and Depression Scale. Physical function was measured using the EORTC QLQ-C30. Results After surgery, about 14 % of the patients were screened with chronic fatigue. For all dimensions of fatigue, only small longitudinal changes could be observed. Psychological distress could be identified as a good predictor of fatigue after but not before surgery. N. Köhler (*) : L. Gansera : M. Friedrich : E. Brähler Department of Medical Psychology and Medical Sociology, University of Leipzig, Philipp-Rosenthal-Straße 55, 04103 Leipzig, Germany e-mail: [email protected] S. Holze : J.
ORIGINAL ARTICLE
Cancer-related fatigue in patients before and after radical prostatectomy. Results of a prospective multi-centre study Norbert Köhler & Lutz Gansera & Sigrun Holze & Michael Friedrich & Udo Rebmann & Jens-Uwe Stolzenburg & Michael C. Truss & Dirk Fahlenkamp & Hans-Jörg Scholz & Elmar Brähler
Received: 2 October 2013 / Accepted: 22 April 2014 # Springer-Verlag Berlin Heidelberg 2014
Abstract Purpose A multi-centre, longitudinal study was conducted to assess the prevalence of fatigue amongst men with localized prostate cancer, to describe several dimensions of fatigue and to explore the predictability of fatigue by psychological distress and physical function. Methods The prevalence of fatigue was evaluated using the Multidimensional Fatigue Inventory in 329 prostate cancer patients before, 3, 6 and 12 months after surgery. Psychological distress was assessed using the Hospital Anxiety and Depression Scale. Physical function was measured using the EORTC QLQ-C30. Results After surgery, about 14 % of the patients were screened with chronic fatigue. For all dimensions of fatigue, only small longitudinal changes could be observed. Psychological distress could be identified as a good predictor of fatigue after but not before surgery. N. Köhler (*) : L. Gansera : M. Friedrich : E. Brähler Department of Medical Psychology and Medical Sociology, University of Leipzig, Philipp-Rosenthal-Straße 55, 04103 Leipzig, Germany e-mail: [email protected] S. Holze : J.
