Cardiac Involvement in Systemic LUPUS Erythematosus Detected by Echocardiography Ian G. Crozier, MD, Edmund Li, MD, Margaret J. Milne, and M. Gary Nicholls, MD

Cardiac invokement in patients with systemic lupus erythematosus (SLE) was amessed by full echocardiography and continuous wave Doppler in 60 consecutive patients and 60 age- and sex-matched control subjects in a prospective, blinded study. The lefl ventricular ejection fraction was &creased in patients compared to control subjects (61 f 9 vs 68 f 7%, p