Postgraduate Medicine

ISSN: 0032-5481 (Print) 1941-9260 (Online) Journal homepage: http://www.tandfonline.com/loi/ipgm20

Case report primary actinomycosis of external oblique muscle Anjaneya R. Puppala & Francis U. Steinheber To cite this article: Anjaneya R. Puppala & Francis U. Steinheber (1978) Case report primary actinomycosis of external oblique muscle, Postgraduate Medicine, 63:4, 179-182, DOI: 10.1080/00325481.1978.11714817 To link to this article: http://dx.doi.org/10.1080/00325481.1978.11714817

Published online: 07 Jul 2016.

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• A 67-year-old man was admitted to Coney Island Hospital, Brooklyn, New York, because of an enlarging, hard mass in the lower right abdominal quadrant that had been present for two weeks. He gave no history of abdominal pain, tenderness, trauma, or straining or of nausea, vomiting, fever, or chills. His appetite was good, and his weight had been stable. He had been constipated for many years; no changes had been noted in bowel habits. Three years previously the patient had had suprapubic cystostomy for bladder stones and transurethral resection for benign prostatic hypertrophy without complications. He also had a history of right-sided hemiparesis and of myocardial infarction of the inferior wall. Blood pressure was 140 I 80 mm Hg, pulse rate was 86/min, respirations were 14/min, and temperature was 98.0 F. The abdomen was nontender, soft, and flat except for a firm, 11 x 8-OE invites submission of brief case reports, especially those related to ambulatory medical care. Illustrations and references should be included only when essential.

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Indication•: Keflex is indicated for the treatment of the following infections when caused by susceptible strains of the designated microorganisms: Respiratory tract 1nfections caused by Streptococcus (Diplococcus) pneumaniae and group A beta-hemolytic streptococci (Penicillin is the usual drug of choice in the treatment and prevention of streptococcal infections, mcluding the prophylaxis of rheumatic fever. Kef lex is generally effective in the eradication of streptococci from the nasopharynx; however, substantial data establishing the efficacy of Kef lex in the subsequent prevention of rheumatic fever are not available at present.) Otitis media due to Str. pneumomae, Hemaphilus inl/uenzae, staphylococci, streptococci, and Neisseria catarrhalis Skin and soft-tissue infections caused by staphylococci and/or streptococci Bone infections caused by staphylococci and/or Proteus mirabil1s Genitourinary tract infections, includmg acute prostatitis, caused by Escherichia coli, Pr. mirab1l1s, and Klebsiella sp. Note-Culture and susceptibility tests should be initiated prior to and during therapy. Renal function studies should be performed when indicated. Contraindication: Keflex is contraindicated in patients with known allergy to the cephalosporin group of antibiotics. Warning•: BEFORE CEPHALEXIN THERAPY IS INSTITUTED, CAREFUL INQUIRY SHOULD BE MADE CONCERNING PREVIOUS HYPERSENSITIVITY REACTIONS TO CEPHALOSPORINS AND PENICILLIN. CEPHALOSPORIN C DERIVATIVES SHOULD BE GIVEN CAUTIOUSLY TO PENICILLIN-SENSITIVE PATIENTS. SERIOUS ACUTE HYPERSENSITIVITY REACTIONS MAY REQUIRE EPINEPHRINE AND OTHER EMERGENCY MEASURES. There 1s some clinical and laboratory evidence of partial cross-allergenicity of the penicillins and the cephalosporins. Patients have been reported to have had severe reactions (including anaphylaxis) to both drugs. Any patient who has demonstrated some form of allergy, particularly to drugs, should receive antibiotics cautiOusly. No exception should be made with regard to Keflex. Usage in Pregnancy-Safety of this product for use during pregnancy has not been established. Prac1ution1: Patients should be followed carefully so that any Side-effects or unusual manifestations of drug idiosyncrasy may be detected. If an allergic reaction to Keflex occurs, the drug should be discontinued and the patient treated w1th the usual agents (e.g., epinephrine or other pressor amines, antthtstamines, or corticosteroids). Prolonged use of Keflex may result in the overgrowth of nonsusceptible organisms. Careful observation of the patient is essential. If superinfection occurs during therapy, appropriate measures should be taken. Positive direct Coombs tests have been reported during treatment with the cephalosporin antibiotics. In hematologic studies or in transfu&lon cross-matching procedures when antiglobulin tests are performed on the minor side or in Coombs testing of newborns whose mothers have received cephalosporin antibiotics before parturition, it should be recognized that a positive Coombs test may be due to the drug. Keflex should be administered with caution in the presence of markedly impaired renal function. Under such conditions, careful clinical observation and laboratory studies should be made because safe dosage may be lower than that usually recommended. Indicated surgical procedures should be performed in conjunction with antibiotic therapy. As a result of administration of Keflex, a false-positive reactton for glucose in the urine may occur. This has been observed with Benedict's and Fehl1ng's solutions and also with Clinitest® tablets but not with Tes-Tape® (Glucose Enzymatic Test Strip, USP, Lilly). Adver•• Reaction•: Gastraintestina/- The most frequent side-effect has been diarrhea. lt was very rarely severe enough to warrant cessation of therapy. Nausea, vomiting, dyspepsia, and abdominal pain have also occurred. Hypersensitivity-Allergies (in the form of rash, urticaria, and angioedema) have been observed. These reactions usually subsided upon discontinuation of the drug. Anaphylaxis has also been reported. Other reactions have included genital and anal pruritus, genital moniliasis, vaginitis and vaginal discharge, diZziness, fatigue, and headache. Eosinophilia, neutropenia, and slight elevations in SGOT and SGPT have been reported. [on4n]

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POSTGRADUATE MEDICINE • April1978 • Vol. 63 • No. 4

Case report: primary actinomycosis of external oblique muscle.

Postgraduate Medicine ISSN: 0032-5481 (Print) 1941-9260 (Online) Journal homepage: http://www.tandfonline.com/loi/ipgm20 Case report primary actinom...
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