Journal of Spinal Disorders and Techniques Publish Ahead of Print DOI:10.1097/BSD.0000000000000229 Cement leakage in percutaneous vertebral augmentation for osteoporotic vertebral compression fractures: analysis of risk factors

Weixing Xie,Daxiang Jin,Hui Ma,Jinyong Ding,Jixi Xu,Shuncong Zhang ,De Liang

Weixing Xie, Medical Master, Department of Orthopaedics, The First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine,Baiyun District, Zip code 510405,GuangZhou City, Guangdong Province, China The authors' highest academic degrees:Master of Medicine e-mail:[email protected] Conflict of interest statement We declare that we have no financial and personal relationships with other people or organizations that can inappropriately influence our work, there is no professional or other personal interest of any nature or kind in any product, service and/or company that could be construed as influencing the position presented in, or the review of, the manuscript entitled, “Cement leakage in percutaneous vertebral augmentation for osteoporotic vertebral compression fractures: analysis of risk factors”. We certify that there is no actual or potential conflict of interest in relation to this article.

Author:Weixing Xie,Daxiang Jin,Hui Ma,Jinyong Ding,Jixi Xu,Shuncong Zhang ,De Liang Date:2014.9.25 Cement leakage in percutaneous vertebral augmentation for osteoporotic vertebral compression fractures: analysis of risk factors

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Abstract Study Design:The risk factors for cement leakage were retrospectively reviewed in 192 patients who underwent percutaneous vertebral augmentation. Objective:To discuss the factors related to the cement leakage in percutaneous vertebral augmentation procedure for the treatment of osteoporotic vertebral compression fractures. Summary of Background Data:Percutaneous vertebral augmentation is widely applied to the treatment of osteoporotic vertebral fractures. Cement leakage is a major complication of this procedure. The risk factors for cement leakage were controversial. Methods:A retrospective review of 192 patients who underwent percutaneous vertebral augmentation was conducted. The following data were recorded: age, gender, bone density, number of fractured vertebrae before surgery, number of treated vertebrae, severity of the treated vertebrae, operative approach, volume of injected bone cement, preoperative vertebral compression ratio, preoperative local kyphosis angle, intraosseous clefts, preoperative vertebral cortical bone defect, and ratio and type of cement leakage. To study the correlation between each factor and cement leakage ratio, bivariate regression analysis was employed to perform univariate analysis, while multivariate linear regression analysis was employed to perform multivariate analysis. Results: The study included 192 patients (282 treated vertebrae), and cement leakage occurred in 100 vertebrae (35.46%). The vertebrae with preoperative cortical bone defects generally exhibited higher cement leakage ratio, and the leakage is typically type C. Vertebrae with intact cortical bones before the procedure tend to experience type-S leakage. Univariate analysis showed that patient age, bone density, number of fractured vertebrae before surgery, and vertebral cortical bone were association with cement leakage ratio (P

Cement Leakage in Percutaneous Vertebral Augmentation for Osteoporotic Vertebral Compression Fractures: Analysis of Risk Factors.

The risk factors for cement leakage were retrospectively reviewed in 192 patients who underwent percutaneous vertebral augmentation (PVA)...
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