EXPERIMENTAL AND THERAPEUTIC MEDICINE 11: 1908-1912, 2016

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Characteristics of CD4+CD25+Foxp3+ regulatory T cells in patients with multiple organ dysfunction syndrome XIUXIAN ZANG, YANFANG JIANG, XIUJIANG LI, YUJUN DU and JUNQI NIU Department of Emergency Medicine, First Hospital of Jilin University, Changchun, Jilin 130021, P.R. China Received December 12, 2014; Accepted February 4, 2016 DOI: 10.3892/etm.2016.3157 Abstract. Multiple organ dysfunction syndrome (MODS) is a systemic inflammation. The aim of the present study was to evaluate the role of CD4+CD25+Foxp3+ regulatory T cells (Treg) in patients with MODS and to determine the association between Treg cells and serum cytokine levels. The percentage of Treg in 42 MODS patients and 10 healthy subjects was evaluated using flow cytometry. Serum levels of cytokines were measured using an enzyme‑linked immunosorbent assay. The percentage of Treg cells was significantly elevated in patients with MODS on Day  1 (P

Characteristics of CD4+CD25+Foxp3+ regulatory T cells in patients with multiple organ dysfunction syndrome.

Multiple organ dysfunction syndrome (MODS) is a systemic inflammation. The aim of the present study was to evaluate the role of CD4+CD25+Foxp3+ regula...
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