ETIOLOGY/OTHER
ARTICLE ANALYSIS & EVALUATION ARTICLE TITLE AND BIBLIOGRAPHIC INFORMATION Association between chronic apical periodontitis and coronary artery disease. Costa THR, de Figueiredo Neto JA, Figueiredo de Oliveira AE, de Figueiredo Lopes e Maia M, de Almeida AL. J Endod 2014;40(2):164-7.
REVIEWER Daniel J. Caplan, DDS, PhD
PURPOSE/QUESTION This article examined sociodemographic characteristics, clinical and laboratory values, and health history factors in evaluating the relationship between chronic apical periodontitis and coronary artery disease.
SOURCE OF FUNDING None mentioned
Chronic Apical Periodontitis Is More Common in Subjects With Coronary Artery Disease SUMMARY Subjects Participants in this cross-sectional study were receiving treatment at the Hemodynamics Service of University Hospital Presidente Dutra, Federal University of Maranh~ao, S~ao Luıs–Maranh~ao, Brazil. Data were analyzed from 103 hospital patients recruited between March 2009 and February 2010. The study sample consisted of 52 men and 41 women (mean age 61.9 years).
Key Exposure/Study Factor This was a cross-sectional analysis so the terms ‘‘exposure’’ and ‘‘outcome’’ (which imply a temporal relationship) are not applicable. However, the text reads from the perspective that the hypothetical exposure variable was the presence of chronic apical periodontitis (CAP) as interpreted from a fullmouth radiographic series. CAP was defined as a score of 3, 4, or 5 using the Periapical Index system developed by Orstavik et al.1
Main Outcome Measure The hypothetical outcome measure was the presence of coronary artery disease (CAD), defined as angiographic evidence of obstruction exceeding 50% in at least one coronary artery.2
Main Results TYPE OF STUDY/DESIGN Cross-sectional
LEVEL OF EVIDENCE Level 2: Limited quality, patientoriented evidence
STRENGTH OF RECOMMENDATION GRADE Not applicable
J Evid Base Dent Pract 2014;14:149-150 1532-3382/$36.00 Ó 2014 Elsevier Inc. All rights reserved. http://dx.doi.org/10.1016/j.jebdp.2014.07.003
Among all the variables considered, only age and CAP were included in the final multivariable logistic regression model describing the relationship between CAP and CAD. Specifically, subjects age $60 years had 6.0 times the odds of having CAD compared to those
ARTICLE ANALYSIS & EVALUATION ARTICLE TITLE AND BIBLIOGRAPHIC INFORMATION Association between chronic apical periodontitis and coronary artery disease. Costa THR, de Figueiredo Neto JA, Figueiredo de Oliveira AE, de Figueiredo Lopes e Maia M, de Almeida AL. J Endod 2014;40(2):164-7.
REVIEWER Daniel J. Caplan, DDS, PhD
PURPOSE/QUESTION This article examined sociodemographic characteristics, clinical and laboratory values, and health history factors in evaluating the relationship between chronic apical periodontitis and coronary artery disease.
SOURCE OF FUNDING None mentioned
Chronic Apical Periodontitis Is More Common in Subjects With Coronary Artery Disease SUMMARY Subjects Participants in this cross-sectional study were receiving treatment at the Hemodynamics Service of University Hospital Presidente Dutra, Federal University of Maranh~ao, S~ao Luıs–Maranh~ao, Brazil. Data were analyzed from 103 hospital patients recruited between March 2009 and February 2010. The study sample consisted of 52 men and 41 women (mean age 61.9 years).
Key Exposure/Study Factor This was a cross-sectional analysis so the terms ‘‘exposure’’ and ‘‘outcome’’ (which imply a temporal relationship) are not applicable. However, the text reads from the perspective that the hypothetical exposure variable was the presence of chronic apical periodontitis (CAP) as interpreted from a fullmouth radiographic series. CAP was defined as a score of 3, 4, or 5 using the Periapical Index system developed by Orstavik et al.1
Main Outcome Measure The hypothetical outcome measure was the presence of coronary artery disease (CAD), defined as angiographic evidence of obstruction exceeding 50% in at least one coronary artery.2
Main Results TYPE OF STUDY/DESIGN Cross-sectional
LEVEL OF EVIDENCE Level 2: Limited quality, patientoriented evidence
STRENGTH OF RECOMMENDATION GRADE Not applicable
J Evid Base Dent Pract 2014;14:149-150 1532-3382/$36.00 Ó 2014 Elsevier Inc. All rights reserved. http://dx.doi.org/10.1016/j.jebdp.2014.07.003
Among all the variables considered, only age and CAP were included in the final multivariable logistic regression model describing the relationship between CAP and CAD. Specifically, subjects age $60 years had 6.0 times the odds of having CAD compared to those
