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Chronic Kidney Disease and Implantable Cardioverter Defibrillator Related Complications: 16 Years of Experience ´ MAURITS S. BUITEN, M.D.,∗ MIHALY K. DE BIE, M.D.,∗ AAFKE C. VAN DER HEIJDEN, M.D.,∗ JORIS I. ROTMANS, M.D., Ph.D.,† MARIANNE BOOTSMA, M.D., Ph.D.,∗ J.H. MARC GROENEVELD, M.D., Ph.D.,‡ RON WOLTERBEEK, M.D.,§ TON J. RABELINK, M.D., Ph.D.,† J.WOUTER JUKEMA, M.D., Ph.D.,∗ MARTIN J. SCHALIJ, M.D., Ph.D.,∗ and LIESELOT VAN ERVEN, M.D., Ph.D.∗ From the ∗ Department of Cardiology, Leiden University Medical Center (LUMC), Leiden, The Netherlands; †Department of Nephrology, LUMC, The Netherlands; ‡Department of Nephrology, MCH, Den Haag, The Netherlands; and §Department of Medical Statistics, LUMC, Leiden, The Netherlands
CKD and ICD Related Complications. Introduction: Implantable cardioverter defibrillator (ICD) implantation has become an accepted therapy for the prevention of sudden cardiac death. However, serious comorbidities such as chronic kidney disease (CKD) are influencing the beneficial effects of ICD therapy. In this study, the association between kidney function and the occurrence of ICD related complications was assessed. Methods: All patients receiving an ICD or cardiac resynchronization therapy-defibrillator between 1996 and 2012 were included. Renal function was categorized as: glomerular filtration rate (GFR) >90, GFR 30–90 or GFR
Chronic Kidney Disease and Implantable Cardioverter Defibrillator Related Complications: 16 Years of Experience ´ MAURITS S. BUITEN, M.D.,∗ MIHALY K. DE BIE, M.D.,∗ AAFKE C. VAN DER HEIJDEN, M.D.,∗ JORIS I. ROTMANS, M.D., Ph.D.,† MARIANNE BOOTSMA, M.D., Ph.D.,∗ J.H. MARC GROENEVELD, M.D., Ph.D.,‡ RON WOLTERBEEK, M.D.,§ TON J. RABELINK, M.D., Ph.D.,† J.WOUTER JUKEMA, M.D., Ph.D.,∗ MARTIN J. SCHALIJ, M.D., Ph.D.,∗ and LIESELOT VAN ERVEN, M.D., Ph.D.∗ From the ∗ Department of Cardiology, Leiden University Medical Center (LUMC), Leiden, The Netherlands; †Department of Nephrology, LUMC, The Netherlands; ‡Department of Nephrology, MCH, Den Haag, The Netherlands; and §Department of Medical Statistics, LUMC, Leiden, The Netherlands
CKD and ICD Related Complications. Introduction: Implantable cardioverter defibrillator (ICD) implantation has become an accepted therapy for the prevention of sudden cardiac death. However, serious comorbidities such as chronic kidney disease (CKD) are influencing the beneficial effects of ICD therapy. In this study, the association between kidney function and the occurrence of ICD related complications was assessed. Methods: All patients receiving an ICD or cardiac resynchronization therapy-defibrillator between 1996 and 2012 were included. Renal function was categorized as: glomerular filtration rate (GFR) >90, GFR 30–90 or GFR
