NEWS & VIEWS CHRONIC KIDNEY DISEASE
Should sodium intake be restricted in patients with CKD? Michel Burnier and Gregoire Wuerzner
A reduction of salt intake to 300 mmol) is associated with increased risks of coronary heart disease, stroke, cardiovascular mortal ity and all-cause mortality,1 the minimum level of dietary sodium that should be rec ommended in the general population and in patients with specific medical conditions (including nephropathies) is controversial. Some data suggest that low sodium intake might be associated with increased rather than reduced mortality in the general popu lation, individuals at high risk of cardio vascular disease and patients with diabetes.2,3 A new analysis of data from the Modification of Diet in Renal Disease (MDRD) Study in nondiabetic patients with chronic kidney disease (CKD) supports these findings.4 Current Kidney Disease: Improving Global Outcomes (KDIGO) guidelines recommend that patients with CKD limit their daily dietary sodium intake to
Should sodium intake be restricted in patients with CKD? Michel Burnier and Gregoire Wuerzner
A reduction of salt intake to 300 mmol) is associated with increased risks of coronary heart disease, stroke, cardiovascular mortal ity and all-cause mortality,1 the minimum level of dietary sodium that should be rec ommended in the general population and in patients with specific medical conditions (including nephropathies) is controversial. Some data suggest that low sodium intake might be associated with increased rather than reduced mortality in the general popu lation, individuals at high risk of cardio vascular disease and patients with diabetes.2,3 A new analysis of data from the Modification of Diet in Renal Disease (MDRD) Study in nondiabetic patients with chronic kidney disease (CKD) supports these findings.4 Current Kidney Disease: Improving Global Outcomes (KDIGO) guidelines recommend that patients with CKD limit their daily dietary sodium intake to
