1336
EXPERIMENTAL AND THERAPEUTIC MEDICINE 9: 1336-1344, 2015
Clinical study of cerebral palsy in 408 children with periventricular leukomalacia QING SHANG1, CAI‑YUN MA1, NAN LV1, ZHONG-LI LV2, YI-BING YAN3, ZHI‑RONG WU1, JING‑JIE LI1, JIA‑LI DUAN1 and CHANG‑LIAN ZHU4 1
Children's Hospital of Zhengzhou, Zhengzhou, Henan 450053; 2Beijing Children's Hospital, Capital Medicine University, Beijing 100045; 3Children's Hospital of Liaocheng, Liaocheng, Shandong 252000, P.R. China; 4 Center for Brain Repair and Rehabilitation, Institute of Neuroscience and Physiology, The University of Gothenburg, Göteborg 40530, Sweden Received March 16, 2014; Accepted September 23, 2014 DOI: 10.3892/etm.2015.2222
Abstract. This study aimed to investigate the high risk factors, cerebral palsy (CP) subtypes and comorbidities of periventricular leukomalacia (PVL). Based on treatment conditions at a specialist hospital, a cross‑sectional clinical study and retrospective analysis of computed tomography and magnetic resonance imaging examinations was conducted to evaluate the risk factors, subtypes and comorbidities of CP in children with PVL. Among the 408 children with PVL, 8.58% were born with a weight of ≤1,500 g and 44.36% were born with a weight of ≥2,500 g. In addition, 36.76% of these children had a gestational age of ≤32 weeks and 37.75% had a gestational age of ≥37 weeks. The proportion of the children born with various high risk factors was 95.59%, including perinatal infections and hypoxia. Severe PVL was observed in preterm infants (63.41% with a gestational age of
EXPERIMENTAL AND THERAPEUTIC MEDICINE 9: 1336-1344, 2015
Clinical study of cerebral palsy in 408 children with periventricular leukomalacia QING SHANG1, CAI‑YUN MA1, NAN LV1, ZHONG-LI LV2, YI-BING YAN3, ZHI‑RONG WU1, JING‑JIE LI1, JIA‑LI DUAN1 and CHANG‑LIAN ZHU4 1
Children's Hospital of Zhengzhou, Zhengzhou, Henan 450053; 2Beijing Children's Hospital, Capital Medicine University, Beijing 100045; 3Children's Hospital of Liaocheng, Liaocheng, Shandong 252000, P.R. China; 4 Center for Brain Repair and Rehabilitation, Institute of Neuroscience and Physiology, The University of Gothenburg, Göteborg 40530, Sweden Received March 16, 2014; Accepted September 23, 2014 DOI: 10.3892/etm.2015.2222
Abstract. This study aimed to investigate the high risk factors, cerebral palsy (CP) subtypes and comorbidities of periventricular leukomalacia (PVL). Based on treatment conditions at a specialist hospital, a cross‑sectional clinical study and retrospective analysis of computed tomography and magnetic resonance imaging examinations was conducted to evaluate the risk factors, subtypes and comorbidities of CP in children with PVL. Among the 408 children with PVL, 8.58% were born with a weight of ≤1,500 g and 44.36% were born with a weight of ≥2,500 g. In addition, 36.76% of these children had a gestational age of ≤32 weeks and 37.75% had a gestational age of ≥37 weeks. The proportion of the children born with various high risk factors was 95.59%, including perinatal infections and hypoxia. Severe PVL was observed in preterm infants (63.41% with a gestational age of
