BALKAN MEDICAL JOURNAL © Trakya University Faculty of Medicine Available at wwv*/.balkanmedicaljournal.org
THE OFFICIAL JOURNAL OF TRAKYA UNIVERSITY FACULTY OF MEDICINE
Balkan Med J 2013: 30: 85-9 • DOI: 10.5152/balkanmedj.2012.097
Original Article
Correlation between Left Ventricular Mass Index and Calcium Metabolism in Patients with Essential Hypertension Ay§en Helvaci, Besinne Çopur, Mine Ada?
Clinic of 2"'' Internal Medicine, Okmeydani Training and Research Hospital, Istanbul, Turkey
ABSTRACT Objective: To deternnine the correlation between left ventricular mass Index and calcium metabolism in patients with essential hypertension. Study Design: Cross sectional case-control study. Material and Methods: Twenty-seven patients with essential hypertension and 20 healthy individuals were compared with respect to calciotropic hormones, left ventricular mass index (LVMI), and urinary and serum biochemical parameters. The correlations between parathormone, vitamin D, and calcitonin levels and LVMI and blood pressure elevation were determined. Results: The parathormone level was significantly higher (p=0.006) and vitamin D level was significantly lower {p=0.01) in the patient group compared with the control group. However, the two groups were similar in terms of albumin-corrected calcium levels, which were within the normal range (p=0.988). The serum sodium (p=0.014) and urinary calcium (p=0.003) levels and LVMI (p0.05). The calcitonin, osteocalciii, PTH, and vitamin D levels were evaluated in both groups. No significant differences existed between the groups with respect to the levels of calcitonin and osteocalcin (p>0.05); however, the PTH level was significantly higher (p=0.006) and the vitamin D level was significantly lower in the patient group compared with the control group (p=0.01). Comparison of the 24-hour urine samples of the patient and control groups revealed a significantly higher urinary calcium level in the patient group (p=0.003). No statistically significant differences existed between the groups in terms of the mean urinary phosphorus, hydroxyproline, and creatinine levels (p>0.05; Table 2).
nary calcium levels (r=0.580, r=0.579 and r=0.502, respectively; p=0.001 for each) were significantly and positively correlated with PTH level, ASBP, and ADBP. Vitamin D and serum calcium levels were not significantly correlated with PTH level, ASBP, or ADBP (Table 3).
Echocardiographic findings We found high left ventricular wall thickness (LVWT) in the patient group, with significantly higher values for LVMI (110.74±14.89 g/m^vs. 85.713+23.990 g/m^, p
THE OFFICIAL JOURNAL OF TRAKYA UNIVERSITY FACULTY OF MEDICINE
Balkan Med J 2013: 30: 85-9 • DOI: 10.5152/balkanmedj.2012.097
Original Article
Correlation between Left Ventricular Mass Index and Calcium Metabolism in Patients with Essential Hypertension Ay§en Helvaci, Besinne Çopur, Mine Ada?
Clinic of 2"'' Internal Medicine, Okmeydani Training and Research Hospital, Istanbul, Turkey
ABSTRACT Objective: To deternnine the correlation between left ventricular mass Index and calcium metabolism in patients with essential hypertension. Study Design: Cross sectional case-control study. Material and Methods: Twenty-seven patients with essential hypertension and 20 healthy individuals were compared with respect to calciotropic hormones, left ventricular mass index (LVMI), and urinary and serum biochemical parameters. The correlations between parathormone, vitamin D, and calcitonin levels and LVMI and blood pressure elevation were determined. Results: The parathormone level was significantly higher (p=0.006) and vitamin D level was significantly lower {p=0.01) in the patient group compared with the control group. However, the two groups were similar in terms of albumin-corrected calcium levels, which were within the normal range (p=0.988). The serum sodium (p=0.014) and urinary calcium (p=0.003) levels and LVMI (p0.05). The calcitonin, osteocalciii, PTH, and vitamin D levels were evaluated in both groups. No significant differences existed between the groups with respect to the levels of calcitonin and osteocalcin (p>0.05); however, the PTH level was significantly higher (p=0.006) and the vitamin D level was significantly lower in the patient group compared with the control group (p=0.01). Comparison of the 24-hour urine samples of the patient and control groups revealed a significantly higher urinary calcium level in the patient group (p=0.003). No statistically significant differences existed between the groups in terms of the mean urinary phosphorus, hydroxyproline, and creatinine levels (p>0.05; Table 2).
nary calcium levels (r=0.580, r=0.579 and r=0.502, respectively; p=0.001 for each) were significantly and positively correlated with PTH level, ASBP, and ADBP. Vitamin D and serum calcium levels were not significantly correlated with PTH level, ASBP, or ADBP (Table 3).
Echocardiographic findings We found high left ventricular wall thickness (LVWT) in the patient group, with significantly higher values for LVMI (110.74±14.89 g/m^vs. 85.713+23.990 g/m^, p
