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Clinical science
Correlation between retinal vessel density profile and circumpapillary RNFL thickness measured with Fourier-domain optical coherence tomography Ivania Pereira,1 Stephanie Weber,1 Stephan Holzer,1 Hemma Resch,1 Barbara Kiss,1 Georg Fischer,2 Clemens Vass1 1
Department of Ophthalmology & Optometry, Medical University Vienna, Vienna, Austria 2 Center for Medical Statistics Informatics and Intelligent Systems, Section for Medical Information Management and Imaging, Medical University Vienna, Vienna, Austria Correspondence to Professor Clemens Vass, Department of Ophthalmology and Optometry, Medical University of Vienna, General Hospital, Währinger Gürtel 18-20, Vienna A-1090, Austria; clemens.vass@ meduniwien.ac.at Received 25 June 2013 Revised 4 November 2013 Accepted 16 December 2013 Published Online First 3 January 2014
To cite: Pereira I, Weber S, Holzer S, et al. Br J Ophthalmol 2014;98: 538–543. 538
ABSTRACT Aim To assess circumpapillary retinal vessel density (RVD) profiles and correlate them with retinal nerve fibre layer (RNFL) thickness measured by Fourier domain optical coherence tomography (FD-OCT). Methods RNFL thickness of 106 healthy volunteers was measured using Cirrus FD-OCT. A proprietary software was developed in MATLAB to assess the thickness and position of circumpapillary retinal vessels using the scanning laser ophthalmoscopy fundus image, centred on the optic disc. The individual retinal vessel positions and thickness values were integrated in a 256sector RVD profile, and intrasubject and intersubject correlations were calculated. Results The mean value±SD for intrasubject correlation between RVD and RNFL was 0.5349±0.1639, with 101 of 106 subjects presenting significant correlation ( p
Clinical science
Correlation between retinal vessel density profile and circumpapillary RNFL thickness measured with Fourier-domain optical coherence tomography Ivania Pereira,1 Stephanie Weber,1 Stephan Holzer,1 Hemma Resch,1 Barbara Kiss,1 Georg Fischer,2 Clemens Vass1 1
Department of Ophthalmology & Optometry, Medical University Vienna, Vienna, Austria 2 Center for Medical Statistics Informatics and Intelligent Systems, Section for Medical Information Management and Imaging, Medical University Vienna, Vienna, Austria Correspondence to Professor Clemens Vass, Department of Ophthalmology and Optometry, Medical University of Vienna, General Hospital, Währinger Gürtel 18-20, Vienna A-1090, Austria; clemens.vass@ meduniwien.ac.at Received 25 June 2013 Revised 4 November 2013 Accepted 16 December 2013 Published Online First 3 January 2014
To cite: Pereira I, Weber S, Holzer S, et al. Br J Ophthalmol 2014;98: 538–543. 538
ABSTRACT Aim To assess circumpapillary retinal vessel density (RVD) profiles and correlate them with retinal nerve fibre layer (RNFL) thickness measured by Fourier domain optical coherence tomography (FD-OCT). Methods RNFL thickness of 106 healthy volunteers was measured using Cirrus FD-OCT. A proprietary software was developed in MATLAB to assess the thickness and position of circumpapillary retinal vessels using the scanning laser ophthalmoscopy fundus image, centred on the optic disc. The individual retinal vessel positions and thickness values were integrated in a 256sector RVD profile, and intrasubject and intersubject correlations were calculated. Results The mean value±SD for intrasubject correlation between RVD and RNFL was 0.5349±0.1639, with 101 of 106 subjects presenting significant correlation ( p
