5025
J Physiol 594.17 (2016) pp 5025–5026
Erratum/Corrigendum
Expression of concern
The Journal of Physiology
With the agreement of the authors, the Editor-in-Chief and the publisher John Wiley & Sons, The Journal of Physiology is publishing four Expressions of Concern regarding four articles that appeared in The Journal between 2009 and 2014. The Journal was alerted to the strong resemblance of western blots in figures in each of these four articles to blots in other figures in the same article and/or in other articles. After investigation by journal staff and experts in the field and consultation with the authors, we could not rule out the possibility that the western blots had been duplicated. All the articles involved have overlapping authorship. The similarity of the western blots raises questions about the reliability of some of the data in the four articles. The authors, the Editor-in-Chief and the publisher considered each paper separately before agreeing that publication of an Expression of Concern for each paper was necessary. The Journal has asked the corresponding authors’ institution to investigate these cases. Eduardo R. Ropelle, Jos´e R. Pauli, Patr´ıcia Prada, Dennys E. Cintra, Guilherme Z. Rocha, Juliana C. Moraes, Marisa J. S. Frederico, Gabrielle da Luz, Ricardo A. Pinho, Jos´e B. C. Carvalheira, Licio A. Velloso, Mario A. Saad & Cl´audio T. De Souza (2009). Inhibition of hypothalamic Foxo1 expression reduced food intake in diet-induced obesity rats. J Physiol, 587(10), pp 2341–2351. DOI 10.1113/jphysiol.2009.170050. The blot used in Figure 2A for alpha-tubulin appears to be repeated for insulin receptor in Figure 3A. The blot used in Figure 2B for alpha-tubulin appears to be repeated for insulin receptor substrate-2 in Figure 3A. The blot used in Figure 2C for alpha-tubulin appears to be repeated for Akt in Figure 3A. The blot used for insulin receptor in Figure 3A appears to be repeated in the following articles/figures: Figure 4B labelled as alpha tubulin in the article: M. A. Carvalho-Filho, E. R. Ropelle, R. J. Pauli, D. E. Cintra, D. M. L. Tsukumo, L. R. Silveira, R. Curi, J. B. C. Carvalheira, L. A. Velloso & M. J. A. Saad (2009). Aspirin attenuates insulin resistance in muscle of diet-induced obese rats by inhibiting inducible nitric oxide synthase production and S-nitrosylation of IRβ/IRS-1 and Akt. Diabetologia, 52(11), 2425–2434. DOI: 10.1007/s00125-009-1498-1. Figure 6K labelled as total p70S6K in the article: Eduardo R. Ropelle, Jose´ R. Pauli, Maria Fernanda A. Fernandes, Silvana A. Rocco, Rodrigo M. Marin, Joseane Morari, Kellen K. Souza, Marı´lia M. Dias, Maria C. Gomes-Marcondes, Jose´ A.R. Gontijo, Kleber G. Franchini, Lı´cio A. Velloso, Mario J.A. Saad, & Jose´ B.C. Carvalheira (2007). A central role for neuronal AMP-activated protein kinase (AMPK) and mammalian target of rapamycin (mTOR) in high-protein diet–induced weight Loss. Diabetes 57(3), 594–605. DOI 10.2337/db07-0573. The other papers on which an Expression of Concern has been issued as a result of this investigation are: Souza Pauli LS, Ropelle EC, de Souza CT, Cintra DE, da Silva AS, de Almeida Rodrigues B, de Moura LP, Marinho R, de Oliveira V, Katashima CK, Pauli JR & Ropelle ER (2014). Exercise training decreases mitogen-activated protein kinase phosphatase-3 expression and suppresses hepatic gluconeogenesis in obese mice. J Physiol, 592(6), 1325–40. DOI: 10.1113/jphysiol.2013.264002. C 2016 The Authors. The Journal of Physiology C 2016 The Physiological Society
DOI: 10.1113/JP272710
5026
Erratum/Corrigendum
J Physiol 594.17
Eduardo R. Ropelle, Jos´e R. Pauli, Dennys E. Cintra, Marisa J. S. Frederico, Ricardo A. De Pinho, L´ıcio A. Velloso & Cl´audio T. De Souza (2009). Acute exercise modulates the Foxo1/PGC-1α pathway in the liver of diet-induced obesity rats. J Physiol. 587(9):2069-76. DOI: 10.1113/jphysiol.2008.164202. Claudio T. De Souza, MarisaJ.S.Frederico, Gabrielle da Luz, DennysE.Cintra, Eduardo R. Ropelle, Jose R.Pauli, and Lıcio A. Velloso(2010). Acute exercise reduces hepatic glucose production through inhibition of the Foxo1/HNF-4α pathway in insulin resistant mice. J Physiol 588.12, 2239–2253.
C 2016 The Authors. The Journal of Physiology C 2016 The Physiological Society
J Physiol 594.17 (2016) pp 5025–5026
Erratum/Corrigendum
Expression of concern
The Journal of Physiology
With the agreement of the authors, the Editor-in-Chief and the publisher John Wiley & Sons, The Journal of Physiology is publishing four Expressions of Concern regarding four articles that appeared in The Journal between 2009 and 2014. The Journal was alerted to the strong resemblance of western blots in figures in each of these four articles to blots in other figures in the same article and/or in other articles. After investigation by journal staff and experts in the field and consultation with the authors, we could not rule out the possibility that the western blots had been duplicated. All the articles involved have overlapping authorship. The similarity of the western blots raises questions about the reliability of some of the data in the four articles. The authors, the Editor-in-Chief and the publisher considered each paper separately before agreeing that publication of an Expression of Concern for each paper was necessary. The Journal has asked the corresponding authors’ institution to investigate these cases. Eduardo R. Ropelle, Jos´e R. Pauli, Patr´ıcia Prada, Dennys E. Cintra, Guilherme Z. Rocha, Juliana C. Moraes, Marisa J. S. Frederico, Gabrielle da Luz, Ricardo A. Pinho, Jos´e B. C. Carvalheira, Licio A. Velloso, Mario A. Saad & Cl´audio T. De Souza (2009). Inhibition of hypothalamic Foxo1 expression reduced food intake in diet-induced obesity rats. J Physiol, 587(10), pp 2341–2351. DOI 10.1113/jphysiol.2009.170050. The blot used in Figure 2A for alpha-tubulin appears to be repeated for insulin receptor in Figure 3A. The blot used in Figure 2B for alpha-tubulin appears to be repeated for insulin receptor substrate-2 in Figure 3A. The blot used in Figure 2C for alpha-tubulin appears to be repeated for Akt in Figure 3A. The blot used for insulin receptor in Figure 3A appears to be repeated in the following articles/figures: Figure 4B labelled as alpha tubulin in the article: M. A. Carvalho-Filho, E. R. Ropelle, R. J. Pauli, D. E. Cintra, D. M. L. Tsukumo, L. R. Silveira, R. Curi, J. B. C. Carvalheira, L. A. Velloso & M. J. A. Saad (2009). Aspirin attenuates insulin resistance in muscle of diet-induced obese rats by inhibiting inducible nitric oxide synthase production and S-nitrosylation of IRβ/IRS-1 and Akt. Diabetologia, 52(11), 2425–2434. DOI: 10.1007/s00125-009-1498-1. Figure 6K labelled as total p70S6K in the article: Eduardo R. Ropelle, Jose´ R. Pauli, Maria Fernanda A. Fernandes, Silvana A. Rocco, Rodrigo M. Marin, Joseane Morari, Kellen K. Souza, Marı´lia M. Dias, Maria C. Gomes-Marcondes, Jose´ A.R. Gontijo, Kleber G. Franchini, Lı´cio A. Velloso, Mario J.A. Saad, & Jose´ B.C. Carvalheira (2007). A central role for neuronal AMP-activated protein kinase (AMPK) and mammalian target of rapamycin (mTOR) in high-protein diet–induced weight Loss. Diabetes 57(3), 594–605. DOI 10.2337/db07-0573. The other papers on which an Expression of Concern has been issued as a result of this investigation are: Souza Pauli LS, Ropelle EC, de Souza CT, Cintra DE, da Silva AS, de Almeida Rodrigues B, de Moura LP, Marinho R, de Oliveira V, Katashima CK, Pauli JR & Ropelle ER (2014). Exercise training decreases mitogen-activated protein kinase phosphatase-3 expression and suppresses hepatic gluconeogenesis in obese mice. J Physiol, 592(6), 1325–40. DOI: 10.1113/jphysiol.2013.264002. C 2016 The Authors. The Journal of Physiology C 2016 The Physiological Society
DOI: 10.1113/JP272710
5026
Erratum/Corrigendum
J Physiol 594.17
Eduardo R. Ropelle, Jos´e R. Pauli, Dennys E. Cintra, Marisa J. S. Frederico, Ricardo A. De Pinho, L´ıcio A. Velloso & Cl´audio T. De Souza (2009). Acute exercise modulates the Foxo1/PGC-1α pathway in the liver of diet-induced obesity rats. J Physiol. 587(9):2069-76. DOI: 10.1113/jphysiol.2008.164202. Claudio T. De Souza, MarisaJ.S.Frederico, Gabrielle da Luz, DennysE.Cintra, Eduardo R. Ropelle, Jose R.Pauli, and Lıcio A. Velloso(2010). Acute exercise reduces hepatic glucose production through inhibition of the Foxo1/HNF-4α pathway in insulin resistant mice. J Physiol 588.12, 2239–2253.
C 2016 The Authors. The Journal of Physiology C 2016 The Physiological Society
