Deletion of C the Uterus
omosome 13 in Leiomyomas of
Aurelia M. Meloni, Urvashi Surti, and Avery A. Sandberg
ABSTRACT: We report two cases of leiomyomas of the uterus with a deletion of the long arm of chromosome 13. To our knowledge this cytogenetic abnormality as a single change has not been reported previously. One of our cases s h o w e d a del(13)(q14q32) an the other a del(13)(q13q33). We
discuss the cases and compare our findings with previous ones reported in the literature.
INTRODUCTION Uterine leiomyomas are benign neoplasms of the smooth muscles and constitute the most common tumor of the uterus. They occur in 20-30% of women over 30 years of age [1, 2]. Malignant transformation is extremely rare; the rate of occurrence is estimated to be
omosome 13 in Leiomyomas of
Aurelia M. Meloni, Urvashi Surti, and Avery A. Sandberg
ABSTRACT: We report two cases of leiomyomas of the uterus with a deletion of the long arm of chromosome 13. To our knowledge this cytogenetic abnormality as a single change has not been reported previously. One of our cases s h o w e d a del(13)(q14q32) an the other a del(13)(q13q33). We
discuss the cases and compare our findings with previous ones reported in the literature.
INTRODUCTION Uterine leiomyomas are benign neoplasms of the smooth muscles and constitute the most common tumor of the uterus. They occur in 20-30% of women over 30 years of age [1, 2]. Malignant transformation is extremely rare; the rate of occurrence is estimated to be
