Int J Colorectal Dis DOI 10.1007/s00384-015-2486-1
LETTER TO THE EDITOR
Diagnosis and treatment for primary small intestinal lymphoma of 59 cases: a follow-up study Jing Xu 1 & Wenwen Lu 2 & Zhe Shen 2 & Feng Ji 2 & Youming Li 2 & Hong Zhang 2
Accepted: 21 December 2015 # Springer-Verlag Berlin Heidelberg 2016
Dear Editor: Primary small intestinal lymphoma (PSIL), accounting for nearly 20–30 % of PGIL, second to gastric lymphoma (60– 70 %), is a rare tumor of digestive tract. PSIL has often been reported as a subset of gastrointestinal lymphoma, which may include gastric lymphoma, in these studies, PSIL had different characteristic and a worse prognosis. But, reports of PSIL are relatively rare, and the treatment and prognostic factors of PSIL varied widely among these studies. Above all, the clinicopathological features of PSIL are less well documented. Thus, we collected and analyzed the clinical data of 59 PSIL patients to strengthen the understanding of PSIL. Jing Xu and Wenwen Lu contributed equally to this study and share first authorship. * Hong Zhang [email protected] Jing Xu [email protected] Wenwen Lu [email protected] Zhe Shen [email protected] Feng Ji [email protected] Youming Li [email protected]
1
Department of Clinical Laboratory, The First Affiliated Hospital, Medical College of Zhejiang University, 79 Qing’chun Road, Hangzhou, Zhejiang Province 310003, China
2
Department of Gastroenterology, The First Affiliated Hospital, Medical College of Zhejiang University, 79 Qing’chun Road, Hangzhou, Zhejiang Province 310003, China
Method Clinical data of 59 PSIL patients treated in The First Affiliated Hospital of Medical School of Zhejiang University between 2006 and 2015 were collected. All the patients were diagnosed as non-Hodgkin lymphoma (NHL) by pathology. Natural courses of all the patients lasted between 1 month and 9 years, 53 out of 59 patients were followed up. Patients were included in the study based on standard diagnostic criteria for primary intestinal lymphoma, as established by Dawson et al. in 1961: There are (i) no superficial enlarged lymph nodes when the patient is first seen; (ii) chest radiographs show no obvious enlargement of the mediastinal nodes; (iii) the white blood cell counts, total and differential, are within normal limits; (iv) at laparotomy, only regional lymph nodes are affected by disease; and (v) the liver and spleen seem free of tumor. Data were performed using SPSS16.0 statistical software. The characteristics and clinicopathological features of the patients were compared using chi-square tests, as appropriate in univariate analyses. Factors with a p value of 0.05). Due to the low number of TCL, together with the poor 1-year survival rate (0 %), we cannot conduct the above analysis. Factors with a p value of
LETTER TO THE EDITOR
Diagnosis and treatment for primary small intestinal lymphoma of 59 cases: a follow-up study Jing Xu 1 & Wenwen Lu 2 & Zhe Shen 2 & Feng Ji 2 & Youming Li 2 & Hong Zhang 2
Accepted: 21 December 2015 # Springer-Verlag Berlin Heidelberg 2016
Dear Editor: Primary small intestinal lymphoma (PSIL), accounting for nearly 20–30 % of PGIL, second to gastric lymphoma (60– 70 %), is a rare tumor of digestive tract. PSIL has often been reported as a subset of gastrointestinal lymphoma, which may include gastric lymphoma, in these studies, PSIL had different characteristic and a worse prognosis. But, reports of PSIL are relatively rare, and the treatment and prognostic factors of PSIL varied widely among these studies. Above all, the clinicopathological features of PSIL are less well documented. Thus, we collected and analyzed the clinical data of 59 PSIL patients to strengthen the understanding of PSIL. Jing Xu and Wenwen Lu contributed equally to this study and share first authorship. * Hong Zhang [email protected] Jing Xu [email protected] Wenwen Lu [email protected] Zhe Shen [email protected] Feng Ji [email protected] Youming Li [email protected]
1
Department of Clinical Laboratory, The First Affiliated Hospital, Medical College of Zhejiang University, 79 Qing’chun Road, Hangzhou, Zhejiang Province 310003, China
2
Department of Gastroenterology, The First Affiliated Hospital, Medical College of Zhejiang University, 79 Qing’chun Road, Hangzhou, Zhejiang Province 310003, China
Method Clinical data of 59 PSIL patients treated in The First Affiliated Hospital of Medical School of Zhejiang University between 2006 and 2015 were collected. All the patients were diagnosed as non-Hodgkin lymphoma (NHL) by pathology. Natural courses of all the patients lasted between 1 month and 9 years, 53 out of 59 patients were followed up. Patients were included in the study based on standard diagnostic criteria for primary intestinal lymphoma, as established by Dawson et al. in 1961: There are (i) no superficial enlarged lymph nodes when the patient is first seen; (ii) chest radiographs show no obvious enlargement of the mediastinal nodes; (iii) the white blood cell counts, total and differential, are within normal limits; (iv) at laparotomy, only regional lymph nodes are affected by disease; and (v) the liver and spleen seem free of tumor. Data were performed using SPSS16.0 statistical software. The characteristics and clinicopathological features of the patients were compared using chi-square tests, as appropriate in univariate analyses. Factors with a p value of 0.05). Due to the low number of TCL, together with the poor 1-year survival rate (0 %), we cannot conduct the above analysis. Factors with a p value of
