CLINICAL RESEARCH e-ISSN 1643-3750 © Med Sci Monit, 2016; 22: 2167-2174 DOI: 10.12659/MSM.896471
Diffusion Tensor Imaging of White Matter Injury Caused by Prematurity-Induced HypoxicIschemic Brain Damage
Received: 2015.10.28 Accepted: 2015.12.14 Published: 2016.06.24
Authors’ Contribution: Study Design A Data Collection B Analysis C Statistical Data Interpretation D Manuscript Preparation E Literature Search F Funds Collection G
ABC 1 CDF 1 DF 1 F 2 ACDE 1
Corresponding Author: Source of support:
Background:
Material/Methods:
Results:
Conclusions:
MeSH Keywords:
Full-text PDF:
Fuyong Zhang* Chunli Liu* Linlin Qian Haifeng Hou Zhengyi Guo
1 Taian City Central Hospital, Taian, Shandong, P.R. China 2 Taishan Medical University, Taian, Shandong, P.R. China
* Those authors contributed equally to this work Zhengyi Guo, e-mail: [email protected] Departmental sources
This investigation aimed to evaluate changes in apparent diffusion coefficient (ADC) and fractional anisotropy (FA) of white matter injury (WMI) in preterm neonates with hypoxic-ischemic encephalopathy (HIE) using diffusion tension imaging (DTI). Thirty-eight neonates less than 37 weeks of gestation with leukoencephalopathy (as observation group) and 38 full-term infants with no leukoencephalopathy (as control group) were selected from the Neonatal Care Center in Taian Central Hospital from January 2012 to December 2013. A DTI scan was obtained within 1 week after birth. In the observation group, on both sides the ADC values in regions of interest (ROI) of white matter, lesions were greater and FA values were lower than in the control group. ADC and FA values in genu and splenum of corpus callosum were statistically different between the mild and severe injury groups (p
Diffusion Tensor Imaging of White Matter Injury Caused by Prematurity-Induced HypoxicIschemic Brain Damage
Received: 2015.10.28 Accepted: 2015.12.14 Published: 2016.06.24
Authors’ Contribution: Study Design A Data Collection B Analysis C Statistical Data Interpretation D Manuscript Preparation E Literature Search F Funds Collection G
ABC 1 CDF 1 DF 1 F 2 ACDE 1
Corresponding Author: Source of support:
Background:
Material/Methods:
Results:
Conclusions:
MeSH Keywords:
Full-text PDF:
Fuyong Zhang* Chunli Liu* Linlin Qian Haifeng Hou Zhengyi Guo
1 Taian City Central Hospital, Taian, Shandong, P.R. China 2 Taishan Medical University, Taian, Shandong, P.R. China
* Those authors contributed equally to this work Zhengyi Guo, e-mail: [email protected] Departmental sources
This investigation aimed to evaluate changes in apparent diffusion coefficient (ADC) and fractional anisotropy (FA) of white matter injury (WMI) in preterm neonates with hypoxic-ischemic encephalopathy (HIE) using diffusion tension imaging (DTI). Thirty-eight neonates less than 37 weeks of gestation with leukoencephalopathy (as observation group) and 38 full-term infants with no leukoencephalopathy (as control group) were selected from the Neonatal Care Center in Taian Central Hospital from January 2012 to December 2013. A DTI scan was obtained within 1 week after birth. In the observation group, on both sides the ADC values in regions of interest (ROI) of white matter, lesions were greater and FA values were lower than in the control group. ADC and FA values in genu and splenum of corpus callosum were statistically different between the mild and severe injury groups (p
