66
Gut, 1991,32,66-69
Do non-steroidal anti-inflammatory drugs increase colonic permeability? A P Jenkins, D R Trew, B J Crump, W S Nukajam, J A Foley, I S Menzies, B Creamer Abstract Urinary excretion of orally administered lactulose and 51 chromium labelled ethylenediamine tetra-acetate (5lCr-EDTA) was measured in 12 healthy adult subjects and in six patients with ileostomies to assess intestinal permeability. In normal subjects, 24 hour urinary recovery of 51Cr-EDTA was significantly greater than that of lactulose (mean (SEM) 2*27 (0-15) v 0*50 (0.08)% oral dose; p
Gut, 1991,32,66-69
Do non-steroidal anti-inflammatory drugs increase colonic permeability? A P Jenkins, D R Trew, B J Crump, W S Nukajam, J A Foley, I S Menzies, B Creamer Abstract Urinary excretion of orally administered lactulose and 51 chromium labelled ethylenediamine tetra-acetate (5lCr-EDTA) was measured in 12 healthy adult subjects and in six patients with ileostomies to assess intestinal permeability. In normal subjects, 24 hour urinary recovery of 51Cr-EDTA was significantly greater than that of lactulose (mean (SEM) 2*27 (0-15) v 0*50 (0.08)% oral dose; p
