Effect of iron on serum 25-hydroxyvitamin dihydroxyvitamin D ,2 Dov

Heldenberg,

Gershon

ABSTRACI’

In 13 of 17 infants

mo) with iron-deficiency vitamin D concentration of these below

13 the

10 g

vitamin

treated

with

D/d

from

treatment

may

despite

Yosef

10.5

± 4.3;

Weisman i ± SD

the

age

iron

increased

of

1 mo.

dextran

the

The

infants

contribute

A intestinal ofvitamin

feeding return

The

iron-

and

serum

iron

24,25-diiron defi-

absorption. Therefore, D may also be impaired.

to the development

ofvitamin

D deficiency.

supplementation may have improved the absorption of vitamin D in the small intestine and hence increased the vitamm D concentration in the plasma. Am J Clin Nutr l992;56: 533-6.

WORDS

deficiency,

Infancy,

iron

iron-deficiency

anemia,

vitamin

D

When

drome.

Our

assumption

may impair soluble, and

plasma. correct tamin

If this assumption

Because

mild

malabsorption

iron-deficiency

is correct,

treatment

with

is fat in the

iron

anemia

is very

of the abundant

sunlight

and

in

is expected

from

infants

1 mo

to be a rare

a few cases

common

regular

of age

of rickets

in infants

D deficiency

in randomly

selected

( 1’.

vitamin

D sup-

vitamin

D defi-

Previously

we di-

on,

phenomenon.

will of vi-

in Israel

with

patients

group

is a regular

abundance

infant

underwent

height

were

of 220000

to Arabs

duration

mothers

is 3:2,

of breast-

were

obliged

to

in Israel

a physical

recorded.

>

1 5%, transferrin electrophoresis.

75

weight

and

was

per-

wrist

red

anemia

mmol/L,

cell

mean

cor-

distribution

width

saturation < I 5%, and a normal Criteria for vitamin D deficiency

25-hydroxyvitamin

D [25(OH)D]

and

24,25-dihydroxyvitamin (2, 3). This study was approved of our

in which

1 .69