Wageningen Academic P u b l i s h e r s
Beneficial Microbes, 2014; 5(4): 403-407
http://www.wageningenacademic.com/doi/pdf/10.3920/BM2013.0089 - Saturday, October 07, 2017 11:23:28 PM - Göteborgs Universitet IP Address:130.241.16.16
Effect of tablets containing probiotic bacteria (Lactobacillus reuteri) on early caries lesions in adolescents: a pilot study M.K. Keller1*, I. Nøhr Larsen2, L. Karlsson3 and S. Twetman1 1Department
of Odontology, Section for Cariology & Endodontics and Pediatric Dentistry & Clinical Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Nørre Allé 20, 2200 Copenhagen N, Denmark; 2Public Dental Clinic, Ishøy Søvej 200, 2635 Ishøy Denmark; 3Department of Dental Medicine, Karolinska Institutet, Huddinge, Hälsovägen, 14186 Stockholm, Sweden; [email protected] Received: 17 December 2013/ Accepted: 18 March 2014 © 2014 Wageningen Academic Publishers
RESEARCH ARTICLE Abstract The objective of the study was to investigate the effect of tablets containing probiotic lactobacilli on early caries lesions in adolescents with quantitative light-induced fluorescence (QLF). 36 healthy adolescents of both sexes (12-17 years of age) were enrolled and randomly allocated to a placebo-controlled trial with two parallel groups. The test group received two tablets daily containing two strains of Lactobacillus reuteri (DSM 17938 and ATCC PTA 5289) for a period of three months, while the control group got identical placebo tablets without live bacteria. The primary outcome was QLF-readings (change in fluorescence, ∆F and lesion area, mm2) at baseline and after 3 months, conducted at two buccal sites of each individual, pre-selected with clearly visible clinical signs of enamel demineralisation (white spots). Significantly more premolars were allocated to the placebo group, while the test group had more incisors (P
Beneficial Microbes, 2014; 5(4): 403-407
http://www.wageningenacademic.com/doi/pdf/10.3920/BM2013.0089 - Saturday, October 07, 2017 11:23:28 PM - Göteborgs Universitet IP Address:130.241.16.16
Effect of tablets containing probiotic bacteria (Lactobacillus reuteri) on early caries lesions in adolescents: a pilot study M.K. Keller1*, I. Nøhr Larsen2, L. Karlsson3 and S. Twetman1 1Department
of Odontology, Section for Cariology & Endodontics and Pediatric Dentistry & Clinical Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Nørre Allé 20, 2200 Copenhagen N, Denmark; 2Public Dental Clinic, Ishøy Søvej 200, 2635 Ishøy Denmark; 3Department of Dental Medicine, Karolinska Institutet, Huddinge, Hälsovägen, 14186 Stockholm, Sweden; [email protected] Received: 17 December 2013/ Accepted: 18 March 2014 © 2014 Wageningen Academic Publishers
RESEARCH ARTICLE Abstract The objective of the study was to investigate the effect of tablets containing probiotic lactobacilli on early caries lesions in adolescents with quantitative light-induced fluorescence (QLF). 36 healthy adolescents of both sexes (12-17 years of age) were enrolled and randomly allocated to a placebo-controlled trial with two parallel groups. The test group received two tablets daily containing two strains of Lactobacillus reuteri (DSM 17938 and ATCC PTA 5289) for a period of three months, while the control group got identical placebo tablets without live bacteria. The primary outcome was QLF-readings (change in fluorescence, ∆F and lesion area, mm2) at baseline and after 3 months, conducted at two buccal sites of each individual, pre-selected with clearly visible clinical signs of enamel demineralisation (white spots). Significantly more premolars were allocated to the placebo group, while the test group had more incisors (P
