Author's Accepted Manuscript Evaluation of Renal Function after Percutaneous Nephrolithotomy: Does the Number or Percutaneous Access Tracts Matter? Ilya Gorbachinsky , Kyle Wood , Marc Colaco , Sij Hemal , Jayadev Mettu , Majid Mirzazadeh , Dean G. Assimos , Jorge Gutierrez-Aćeves
PII: DOI: Reference:
S0022-5347(16)03246-8 10.1016/j.juro.2016.01.121 JURO 13523
To appear in: The Journal of Urology Accepted Date: 29 January 2016 Please cite this article as: Gorbachinsky I, Wood K, Colaco M, Hemal S, Mettu J, Mirzazadeh M, Assimos DG, Gutierrez-Aćeves J, Evaluation of Renal Function after Percutaneous Nephrolithotomy: Does the Number or Percutaneous Access Tracts Matter?, The Journal of Urology® (2016), doi: 10.1016/j.juro.2016.01.121. DISCLAIMER: This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our subscribers we are providing this early version of the article. The paper will be copy edited and typeset, and proof will be reviewed before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to The Journal pertain.
Embargo Policy All article content is under embargo until uncorrected proof of the article becomes available online. We will provide journalists and editors with full-text copies of the articles in question prior to the embargo date so that stories can be adequately researched and written. The standard embargo time is 12:01 AM ET on that date. Questions regarding embargo should be directed to [email protected].
ACCEPTED MANUSCRIPT
Evaluation of Renal Function after Percutaneous Nephrolithotomy: Does the Number or Percutaneous Access Tracts Matter? Running Title: Renal Function Assessment following Multi-Access PCNL
RI PT
Ilya Gorbachinsky M.D.1, Kyle Wood M.D.1, Marc Colaco M.D.1, Sij Hemal B.S.E.1 , Jayadev Mettu M.D.1, Majid Mirzazadeh M.D.1, Dean G. Assimos M.D.2, Jorge Gutierrez-Aćeves M.D.1
Corresponding Author:
M AN U
Sij Hemal, M.D. Candidate, Class of 2016 Wake Forest School of Medicine Department of Urology 1 Medical Center Blvd., Winston Salem, NC 27106 Phone: +(01)-734-646-8530 [email protected]
SC
1. Department of Urology, Wake Forest Baptist Medical Center, Winston Salem, NC 2. Department of Urology, University of Alabama, Birmingham, AL
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Contact Information for Other Authors
EP
Ilya Gorbachinsky: [email protected] Kyle Wood: [email protected] Marc Colaco: [email protected] Jayadev Mettu: [email protected] Majid Mirzazadeh: [email protected] Dean Assimos: [email protected] Jorge Gutierrez-Aćeves:[email protected]
AC C
Keywords: PCNL; MAG-3; percutaneous nephrolithotomy; nephrolithiasis; renography Word Count:
Abstract: 201
Manuscript: 2498
1
ACCEPTED MANUSCRIPT
ABSTRACT Introduction
RI PT
Renal function following percutaneous nephrolithotomy (PCNL) has long been a concern to urologists, especially in the setting of multi-tract access. We undertook a study to determine if the risk of renal injury after multi-tract PCNL was greater than with a single access approach. Materials and Methods
SC
We performed a retrospective review of 307 consecutive patients undergoing PCNL from 20112012 at Wake Forest Health. Perioperative Tc99m-MAG3 nuclear renogram parameters along with serum creatinine values were assessed within 1 year of the procedure. Patients were stratified by single vs multi-access (≥2).
M AN U
Results
Conclusion
TE D
We identified 110 cases in which renography was done both before and after PCNL. A total of 74 patients (67.3%) underwent single access PCNL while 36 (32.7%) underwent multi-access PCNL. Serum creatinine was not significantly different between the two cohorts postoperatively (p=0.09). There was a significant decrease in the renal function based on MAG3 nuclear renogram results following PCNL of the affected kidney in patients with multiple accesses (2.28% decrease, p
PII: DOI: Reference:
S0022-5347(16)03246-8 10.1016/j.juro.2016.01.121 JURO 13523
To appear in: The Journal of Urology Accepted Date: 29 January 2016 Please cite this article as: Gorbachinsky I, Wood K, Colaco M, Hemal S, Mettu J, Mirzazadeh M, Assimos DG, Gutierrez-Aćeves J, Evaluation of Renal Function after Percutaneous Nephrolithotomy: Does the Number or Percutaneous Access Tracts Matter?, The Journal of Urology® (2016), doi: 10.1016/j.juro.2016.01.121. DISCLAIMER: This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our subscribers we are providing this early version of the article. The paper will be copy edited and typeset, and proof will be reviewed before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to The Journal pertain.
Embargo Policy All article content is under embargo until uncorrected proof of the article becomes available online. We will provide journalists and editors with full-text copies of the articles in question prior to the embargo date so that stories can be adequately researched and written. The standard embargo time is 12:01 AM ET on that date. Questions regarding embargo should be directed to [email protected].
ACCEPTED MANUSCRIPT
Evaluation of Renal Function after Percutaneous Nephrolithotomy: Does the Number or Percutaneous Access Tracts Matter? Running Title: Renal Function Assessment following Multi-Access PCNL
RI PT
Ilya Gorbachinsky M.D.1, Kyle Wood M.D.1, Marc Colaco M.D.1, Sij Hemal B.S.E.1 , Jayadev Mettu M.D.1, Majid Mirzazadeh M.D.1, Dean G. Assimos M.D.2, Jorge Gutierrez-Aćeves M.D.1
Corresponding Author:
M AN U
Sij Hemal, M.D. Candidate, Class of 2016 Wake Forest School of Medicine Department of Urology 1 Medical Center Blvd., Winston Salem, NC 27106 Phone: +(01)-734-646-8530 [email protected]
SC
1. Department of Urology, Wake Forest Baptist Medical Center, Winston Salem, NC 2. Department of Urology, University of Alabama, Birmingham, AL
TE D
Contact Information for Other Authors
EP
Ilya Gorbachinsky: [email protected] Kyle Wood: [email protected] Marc Colaco: [email protected] Jayadev Mettu: [email protected] Majid Mirzazadeh: [email protected] Dean Assimos: [email protected] Jorge Gutierrez-Aćeves:[email protected]
AC C
Keywords: PCNL; MAG-3; percutaneous nephrolithotomy; nephrolithiasis; renography Word Count:
Abstract: 201
Manuscript: 2498
1
ACCEPTED MANUSCRIPT
ABSTRACT Introduction
RI PT
Renal function following percutaneous nephrolithotomy (PCNL) has long been a concern to urologists, especially in the setting of multi-tract access. We undertook a study to determine if the risk of renal injury after multi-tract PCNL was greater than with a single access approach. Materials and Methods
SC
We performed a retrospective review of 307 consecutive patients undergoing PCNL from 20112012 at Wake Forest Health. Perioperative Tc99m-MAG3 nuclear renogram parameters along with serum creatinine values were assessed within 1 year of the procedure. Patients were stratified by single vs multi-access (≥2).
M AN U
Results
Conclusion
TE D
We identified 110 cases in which renography was done both before and after PCNL. A total of 74 patients (67.3%) underwent single access PCNL while 36 (32.7%) underwent multi-access PCNL. Serum creatinine was not significantly different between the two cohorts postoperatively (p=0.09). There was a significant decrease in the renal function based on MAG3 nuclear renogram results following PCNL of the affected kidney in patients with multiple accesses (2.28% decrease, p
