Journal of Clinical and Experimental Neuropsychology, 2014 Vol. 36, No. 6, 636–647, http://dx.doi.org/10.1080/13803395.2014.925092
Executive function and depressive symptoms of retardation in nonelderly stroke patients Matildes F. M. Sobreiro1, Eliane Correa Miotto2, Luisa Terroni1, Gisela Tinone2, Dan V. Iosifescu3, Mara C. S. de Lucia4, Milberto Scaff2, Claudia da Costa Leite5, Edson Amaro Jr.5, and Renerio Fraguas1 1
Consultation–Liaison Psychiatry Group, Department and Institute of Psychiatry, Clinics Hospital, University of São Paulo School of Medicine, São Paulo, Brazil 2 Department of Neurology, Central Institute, Clinics Hospital, University of São Paulo School of Medicine, São Paulo, Brazil 3 Mood and Anxiety Disorders Program, Icahn School of Medicine at Mount Sinai, New York, NY, USA 4 Division of Psychology Central Institute, Clinics Hospital, University of São Paulo School of Medicine, São Paulo, Brazil 5 Department of Radiology, Clinics Hospital, University of São Paulo School of Medicine, São Paulo, Brazil (Received 13 June 2013; accepted 12 May 2014) The depression–executive dysfunction syndrome, a late-onset depression of vascular origin with executive dysfunction and psychomotor retardation, has also been described after stroke. We verified whether this syndrome also occurs in nonelderly stroke patients by investigating the association between domains of depressive symptoms with executive functions in 87 first-ever ischemic stroke patients. The retardation domain of the 31-item Hamilton Rating Scale for Depression was associated with decreased performance on verbal fluency (assessed with FAS). The association was maintained for younger patients (aged
Executive function and depressive symptoms of retardation in nonelderly stroke patients Matildes F. M. Sobreiro1, Eliane Correa Miotto2, Luisa Terroni1, Gisela Tinone2, Dan V. Iosifescu3, Mara C. S. de Lucia4, Milberto Scaff2, Claudia da Costa Leite5, Edson Amaro Jr.5, and Renerio Fraguas1 1
Consultation–Liaison Psychiatry Group, Department and Institute of Psychiatry, Clinics Hospital, University of São Paulo School of Medicine, São Paulo, Brazil 2 Department of Neurology, Central Institute, Clinics Hospital, University of São Paulo School of Medicine, São Paulo, Brazil 3 Mood and Anxiety Disorders Program, Icahn School of Medicine at Mount Sinai, New York, NY, USA 4 Division of Psychology Central Institute, Clinics Hospital, University of São Paulo School of Medicine, São Paulo, Brazil 5 Department of Radiology, Clinics Hospital, University of São Paulo School of Medicine, São Paulo, Brazil (Received 13 June 2013; accepted 12 May 2014) The depression–executive dysfunction syndrome, a late-onset depression of vascular origin with executive dysfunction and psychomotor retardation, has also been described after stroke. We verified whether this syndrome also occurs in nonelderly stroke patients by investigating the association between domains of depressive symptoms with executive functions in 87 first-ever ischemic stroke patients. The retardation domain of the 31-item Hamilton Rating Scale for Depression was associated with decreased performance on verbal fluency (assessed with FAS). The association was maintained for younger patients (aged
