118 Liu et al

World J Emerg Wed, Vol 1, No 2, 2010

Original Article

Factors affecting daily activities of patients with cerebral infarction Peng Liu, Cheng-ye Zhou, Ying Zhang, Yun-feng Wang, Chang-lin Zou Encephalopathy Center, First Affiliated Hospital of Wenzhou Medical College, 325000 Wenzhou, China Corresponding Author: Peng Liu, Email: [email protected]

BACKGROUND: Stroke is the leading cause of death and long-term disability. This study was undertaken to investigate the factors influencing daily activities of patients with cerebral infarction so as to take interventional measures earlier to improve their daily activities. METHODS: A total of 149 patients with first-episode cerebral infarction were recruited into this prospective study. They were admitted to the Encephalopathy Center, Department of Neurology, the First Affiliated Hospital of Wenzhou Medical College in Zhejiang Province from August 2008 to December 2008. The baseline characteristics of the patients and cerebral infarction risk factors on the first day of admission were recorded. White blood cell (WBC) count, plasma glucose (PG), and many others of laboratory targets were collected in the next morning. Barthel index (BI) was calculated at 2 weeks and 3 months respectively after onset of the disease at the outpatient clinic or by telephone call. Lung infection, urinary tract infection and atrial fibrillation if any were recorded on admission. The National Institute of Health Stroke Scale (NIHSS) scores and the GCS scores were recorded within 24 hours on and after admission, at the second week, and at the third month after the onset of cerebral infarction respectively. RESULTS: The factors of BI at 2 weeks and 3 months after onset were the initial PG level, WBC count and initial NIHSS scores. Besides, urinary tract infection on admission was also the factor for BI at 3 months. CONCLUSION: Active measures should be taken to control these factors to improve the daily activities of patients with cerebral infarction. KEY WORDS: Cerebral infarction; Barthel index; Multiple linear regression analysis World J Emerg Med 2010;1(2):118-121

INTRODUCTION Stroke is the second leading cause of death and the main reason for long-term disability. A high degree of disability makes patients lose the daily activities and the ability to work. Therefore, it is necessary to find out the risk factors affecting the daily activities to improve the prognosis of patients with cerebral infarction.

METHODS Patients Altogether 149 consecutive patients with firstepisode cerebral infarction were recruited into this prospective study. They were admitted to the www.wjem.org © 2010 World Journal of Emergency Medicine

Encephalopathy Center of the Department of Neurology, the First Affiliated Hospital of Wenzhou Medical College from August 2008 to December 2008. The patients met the following criteria: first-episode cerebral infarction, one of the National Criteria for Diagnosis of Cerebrovascular Diseases issued in 1995, confirmed by CT or MRI; age≥18 years old; and the time between onset of symptoms to admission≤14 days. Those were excluded according to the following criteria: no symptoms or signs of silent cerebral infarction; noncerebral vascular diseases; and transient ischemic attack.

Methods Of the 149 patients aged 30 to 89 years (average

World J Emerg Med, Vol 1, No 2, 2010

64.67±12.235 years), 89 were male and 60 were female. Their demographic data and factors of ischemic stroke risk were recorded on admission. The National Institute of Health Stroke Scale (NIHSS)[1] scores and GCS scores were taken simultaneously. Red blood cell (RBC) count, white blood cell (WBC) count, platelets, fibrinogens, fasting plasma glucose (PG), low-density lipoprotein, uric acid, calcium, serum magnesium, D-Dmier, neuron-specific enolase (NSE), serum ferritin and other laboratory parameters were measured in the next morning after admission. NIHSS scores and Barthel index (BI) scores were taken on the 14th day after stroke. Lung infection and urinary tract infection were recorded during hospitalization. NIHSS and BI scores were recorded at 2 weeks after onset, and BI scores were recorded again at 3 months after onset by out-patient visit or telephone call. We set the following criteria: WBC≥10×109/L for a higher group,

Factors affecting daily activities of patients with cerebral infarction.

Stroke is the leading cause of death and long-term disability. This study was undertaken to investigate the factors influencing daily activities of pa...
264KB Sizes 1 Downloads 6 Views