894
Correspondence
159. 1976) reported one fetal death seven clays folio\\ing a negative OCT. In a Letter to the Editors (AM. .J ORSTET. GYNF,COI.. 123: 106. 1975). Dr. Baskett related two additional fetal deaths in utero. preceded six and a half days by negative OCT’s. Dr. Klapholr r-worded the earhest fetal death occurring only six hours atict. ;I negative OCT (J. Reprod. Med. lci: 169. 197.5). Our experience of 255 negative OCT’s in 140 highrisk patients favorably supports previous data. I-IO\\ever, one exception has bern noted.
positive) of accepting the difference of the two rates as being significant. Since the mean values (rates) are used as a guide, we feel quite justified in our conservative approach to minimize both the false positive (Type I) and false negative (Type II) errors. Nevertheless, Mr. Sivin’s conclusion that further investigation might be ot‘ value is well taken. Dnniol R. Mkhrll. Jr,, M.D. ProJbssor and Assaciak Chairman Woman’s Hospital 1240 North illi.uion Road Los Angeles. California 90033
A primigravid patient with an uncomplicated pregnancy at 43 weeks’ gestation by firm dates and third-trimester untrasound examination had initiation of monitoring by OC7”s and triweekly estriol determinations. The first estriol level was IOM normal (12 mg per 24 hours). An
Correspondence
159. 1976) reported one fetal death seven clays folio\\ing a negative OCT. In a Letter to the Editors (AM. .J ORSTET. GYNF,COI.. 123: 106. 1975). Dr. Baskett related two additional fetal deaths in utero. preceded six and a half days by negative OCT’s. Dr. Klapholr r-worded the earhest fetal death occurring only six hours atict. ;I negative OCT (J. Reprod. Med. lci: 169. 197.5). Our experience of 255 negative OCT’s in 140 highrisk patients favorably supports previous data. I-IO\\ever, one exception has bern noted.
positive) of accepting the difference of the two rates as being significant. Since the mean values (rates) are used as a guide, we feel quite justified in our conservative approach to minimize both the false positive (Type I) and false negative (Type II) errors. Nevertheless, Mr. Sivin’s conclusion that further investigation might be ot‘ value is well taken. Dnniol R. Mkhrll. Jr,, M.D. ProJbssor and Assaciak Chairman Woman’s Hospital 1240 North illi.uion Road Los Angeles. California 90033
A primigravid patient with an uncomplicated pregnancy at 43 weeks’ gestation by firm dates and third-trimester untrasound examination had initiation of monitoring by OC7”s and triweekly estriol determinations. The first estriol level was IOM normal (12 mg per 24 hours). An
