Accepted Manuscript Title: Field-Flow Fractionation of Nano- and Microparticles in Rotating Coiled Columns Author: Petr S. Fedotov Mikhail S. Ermolin Olesya N. Katasonova PII: DOI: Reference:
S0021-9673(15)00005-9 http://dx.doi.org/doi:10.1016/j.chroma.2014.12.079 CHROMA 356152
To appear in:
Journal of Chromatography A
Received date: Revised date: Accepted date:
31-10-2014 27-12-2014 29-12-2014
Please cite this article as: P.S. Fedotov, M.S. Ermolin, O.N. Katasonova, Field-Flow Fractionation of Nano- and Microparticles in Rotating Coiled Columns, Journal of Chromatography A (2015), http://dx.doi.org/10.1016/j.chroma.2014.12.079 This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
1
Field-Flow Fractionation of Nano- and Microparticles in Rotating
2
Coiled Columns
3
Petr S. Fedotova,b, Mikhail S. Ermolina,b,* and Olesya N. Katasonovab
ip t
4 5
a
6
Moscow, Russia, e-mail: [email protected], [email protected];
7
b
8
19 Kosygin street, 119991 Moscow, Russia, e-mail: [email protected].
cr
National University of Science and Technology “MISiS”, 4 Leninsky Prospect, 119049
us
Vernadsky Institute of Geochemistry and Analytical Chemistry, Russian Academy of Sciences,
an
9
*Corresponding Author. Tel. +7-499-137-8608
11
E-mail address: [email protected] (Mikhail S. Ermolin)
M
10
Ac ce p
te
d
12
Page 1 of 31
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HIGHLIGHTS
Sedimentation field-flow fractionation in rotating roiled columns is discussed. The method allows one to increase the weight of handling particulate samples. Fractionation and quantitative analysis of samples like soil and dust are possible. The method can be used for the preparative separation of partilulate materials.
ip t
13 14 15 16 17 18 19
cr
20
ABSTRACT
22
Field-flow fractionation (FFF) is a very powerful and versatile set of liquid chromatography-like
23
elution methods. However, conventional FFF separations occur in thin channels and the sample
24
weight injected is usually less than 1 mg to avoid overloading. The fractionation in a rotating
25
coiled column (RCC), which can be attributed to sedimentation FFF, enables the handling
26
sample weight to be increased at least up to 1 g. An uneven distribution of particles in RCC was
27
first observed by Y. Ito et al. in 1966. The work in this direction was continued by P.S. Fedotov
28
et al. in 2000. Regularities of the behaviour of nano- and microparticles of different size and
29
origin in RCCs with different design parameters were systematically studied taking as example
30
silica particles, latex beads, quartz sand, clay minerals, and other samples. The basic principles
31
of the new FFF method were established. The developed method was applied to the speciation
32
analysis of polydisperse environmental samples, in particular, for the separation of soils into silt,
33
clay and sand fractions. For the first time, nano- and submicron particles of street dust have been
34
separated, weighted, characterized by electronic microscopy, and quantitatively analyzed by
35
ICP-MS (after digestion). The elements that may be of anthropogenic origin (Zn, Cr, Ni, Cu, Cd,
36
Sn, Pb) were found to concentrate mainly in
S0021-9673(15)00005-9 http://dx.doi.org/doi:10.1016/j.chroma.2014.12.079 CHROMA 356152
To appear in:
Journal of Chromatography A
Received date: Revised date: Accepted date:
31-10-2014 27-12-2014 29-12-2014
Please cite this article as: P.S. Fedotov, M.S. Ermolin, O.N. Katasonova, Field-Flow Fractionation of Nano- and Microparticles in Rotating Coiled Columns, Journal of Chromatography A (2015), http://dx.doi.org/10.1016/j.chroma.2014.12.079 This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
1
Field-Flow Fractionation of Nano- and Microparticles in Rotating
2
Coiled Columns
3
Petr S. Fedotova,b, Mikhail S. Ermolina,b,* and Olesya N. Katasonovab
ip t
4 5
a
6
Moscow, Russia, e-mail: [email protected], [email protected];
7
b
8
19 Kosygin street, 119991 Moscow, Russia, e-mail: [email protected].
cr
National University of Science and Technology “MISiS”, 4 Leninsky Prospect, 119049
us
Vernadsky Institute of Geochemistry and Analytical Chemistry, Russian Academy of Sciences,
an
9
*Corresponding Author. Tel. +7-499-137-8608
11
E-mail address: [email protected] (Mikhail S. Ermolin)
M
10
Ac ce p
te
d
12
Page 1 of 31
12
HIGHLIGHTS
Sedimentation field-flow fractionation in rotating roiled columns is discussed. The method allows one to increase the weight of handling particulate samples. Fractionation and quantitative analysis of samples like soil and dust are possible. The method can be used for the preparative separation of partilulate materials.
ip t
13 14 15 16 17 18 19
cr
20
ABSTRACT
22
Field-flow fractionation (FFF) is a very powerful and versatile set of liquid chromatography-like
23
elution methods. However, conventional FFF separations occur in thin channels and the sample
24
weight injected is usually less than 1 mg to avoid overloading. The fractionation in a rotating
25
coiled column (RCC), which can be attributed to sedimentation FFF, enables the handling
26
sample weight to be increased at least up to 1 g. An uneven distribution of particles in RCC was
27
first observed by Y. Ito et al. in 1966. The work in this direction was continued by P.S. Fedotov
28
et al. in 2000. Regularities of the behaviour of nano- and microparticles of different size and
29
origin in RCCs with different design parameters were systematically studied taking as example
30
silica particles, latex beads, quartz sand, clay minerals, and other samples. The basic principles
31
of the new FFF method were established. The developed method was applied to the speciation
32
analysis of polydisperse environmental samples, in particular, for the separation of soils into silt,
33
clay and sand fractions. For the first time, nano- and submicron particles of street dust have been
34
separated, weighted, characterized by electronic microscopy, and quantitatively analyzed by
35
ICP-MS (after digestion). The elements that may be of anthropogenic origin (Zn, Cr, Ni, Cu, Cd,
36
Sn, Pb) were found to concentrate mainly in
