PostScript the endometrium, and a summary of all seven previously reported cases. Accurate histological interpretation is essential for distinguishing extranodal marginal zone lymphoma from reactive lymphoid aggregates and other B cell lymphomas to ensure optimal management. Anita J Merritt,1 Patrick Shenjere,2 Lia P Menasce,2 Fiona Reid,3 Tim Diss,4 Rhona J McVey,1 Richard J Byers1,5 1

Department of Histopathology, Manchester Royal Infirmary, Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK 2 Department of Histopathology, The Christie NHS Foundation Trust, Manchester, UK 3 Department of Gynaecology, St Marys Hospital, Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK 4 Department of Pathology, UCL-Advanced Diagnostics, University College London, London, UK 5 Institute of Cancer Sciences, The University of Manchester, Manchester, UK Correspondence to Dr Richard Byers, Department of Histopathology, Clinical Sciences Building One, Manchester Royal Infirmary, Oxford Road, Manchester M13 9WL, UK; [email protected] and [email protected] Contributors AJM wrote the manuscript. PS, LPM, RJMcV and RJB made the diagnosis and wrote the manuscript. FR provided clinical liaison and treated the patient. TD undertook scientific analysis detailed in the case report. Competing interests None. Patients Consent Obtained. Provenance and peer review Not commissioned; internally peer reviewed. To cite Merritt AJ, Shenjere P, Menasce L P, et al. J Clin Pathol 2014;67:375–377. Received 20 November 2013 Accepted 24 November 2013 Published Online First 18 December 2013 J Clin Pathol 2014;67:375–377. doi:10.1136/jclinpath-2013-202059







Chorlton I, Karnei RF Jr, King FM, et al. Primary malignant reticuloendothelial disease involving the vagina, cervix, and corpus uteri. Obstet Gynecol 1974;44:735–48. Annibali O, Romeo AA, Agostinelli C, et al. A case of primary MALT lymphoma of the endometrium presenting as an asymptomatic polyp. Ann Hematol 2009;88:491–3. Heeren JHM, Croonen AM, Pijnenborg JMA. Primary extranodal marginal zone B-cell lymphoma of the female genital tract: a case report and literature review. Int J Gynecol Pathol 2008;27:243–6. Hamadani M, Kharfan-Dabaja M, Kamble R, et al. Marginal zone B-cell lymphoma of the uterus: a case report and review of the literature. J Okla State Med Assoc 2006;99:154–6. Frey NV, Svoboda J, Andreadis C, et al. Primary lymphomas of the cervix and uterus: the University of Pennsylvania’s experience and a review of the literature. Leuk Lymphoma 2006;47:1894–901. Iyengar P, Deodhare S. Primary extranodal marginal zone B-cell lymphoma of MALT type of the endometrium. Gynecol Oncol 2004;93:238–41.

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Ballesteros E, Osborne BM, Matsushima AY. CD5+ low-grade marginal zone B-cell lymphomas with localized presentation. Am J Surg Pathol 1998;22:201–7. Wright T, Rule S, Liu H, et al. Extranodal marginal zone lymphoma of the uterine corpus. Leuk Lymphoma 2012;53:1831–4.

Focal nodular hyperplasia-like lesion in a cirrhotic liver mimicking a cholangiocarcinoma INTRODUCTION Focal nodular hyperplasia (FNH) is a common benign liver lesion composed of nodules of proliferating hepatocytes, malformed vessels, and bile ductular proliferation. Classically, FNH has been reported in livers which are normal or near normal. Recently, however, FNH-like lesions have been reported in cirrhotic livers and, as such, FNH should be considered in the clinicopathologic differential diagnosis of hepatocellular carcinoma (HCC) and other nodular liver lesions.1–3 As most of these lesions are detected by imaging studies, it is useful to review the imaging characteristics of FNH. Classical FNH usually has typical imaging characteristics. On unenhanced scans, the lesion is homogenous and well defined and may be either hypo- or iso-dense. It shows bright enhancement on the early arterial phase before becoming iso-dense on the portal phase. The characteristic stellate central scar is hypo-dense on early arterial and portal phases before becoming hyperdense on delayed scans. This, however, is only seen in

Focal nodular hyperplasia-like lesion in a cirrhotic liver mimicking a cholangiocarcinoma.

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