Immunology Today January 1982

Pregnancy

Interferon

From clones to clinic J o h n M o r s e r rep,rl.s ~?ore arl interTmliona/ cong~e.ss ,m interferort, held in San Francisco, Orloher 21-2&

Progress towards an understanding of the molecular biology of interferon has been spectacular but the pace of clinical research has been slower. I. Gresser (Villeneuf) opened the congress with the Kurt Paucker memorial lecture on the theme that 'the unex-

pected is still there'. The unforseen has emerged in the effects of interferons (IFNs) on virus growth and on lymphocyte circulation in ~,iro, their role in inducing disease, and their ability to return the transformed phenotype to normal. The congress was to

Induced ceils 18S mRNA known to code for IFN- 7 I I I I I I I

Reverse transcdptase; DNA polymerase Double-strandedDNA

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Plasmids with DNA insert

nitrocellulose discs

Non induced Colonies lysed. DNA sticks to surface

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From clones to clinic.

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