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BJO Online First, published on September 10, 2014 as 10.1136/bjophthalmol-2014-305361 Clinical science
Ganglion cell and inner plexiform layer thickness determined by spectral domain optical coherence tomography in patients with brain lesions Haein Moon, Joo Young Yoon, Hyun Taek Lim, Kyung Rim Sung Department of Ophthalmology, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, South Korea Correspondence to Dr Kyung Rim Sung, Department of Ophthalmology, University of Ulsan, College of Medicine, Asan Medical Center, 388-1 Pungnap-2dong, Songpa-gu, Seoul 138-736, South Korea; [email protected] HM and JYY contributed equally. Received 7 April 2014 Revised 31 July 2014 Accepted 25 August 2014
To cite: Moon H, Yoon JY, Lim HT, et al. Br J Ophthalmol Published Online First: [ please include Day Month Year] doi:10.1136/bjophthalmol2014-305361
ABSTRACT Purpose To evaluate the thickness of the macular ganglion cell and inner plexiform layer (GCIPL) using spectral domain optical coherence tomography (SD OCT) in patients with brain lesions. Methods This case-control study included 58 healthy subjects and 98 patients with brain lesions confirmed by MRI. GCIPL and peripapillary retinal nerve fiber layer ( pRNFL) thicknesses were determined using the Cirrus SD OCT. Area under the receiver operating characteristic curve (AUC) values of pRNFL and GCIPL thickness were used to discriminate patients with brain lesions from normal controls. Results Average GCIPL thickness showed a good correlation with visual field mean deviation (r2=0.342, p
BJO Online First, published on September 10, 2014 as 10.1136/bjophthalmol-2014-305361 Clinical science
Ganglion cell and inner plexiform layer thickness determined by spectral domain optical coherence tomography in patients with brain lesions Haein Moon, Joo Young Yoon, Hyun Taek Lim, Kyung Rim Sung Department of Ophthalmology, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, South Korea Correspondence to Dr Kyung Rim Sung, Department of Ophthalmology, University of Ulsan, College of Medicine, Asan Medical Center, 388-1 Pungnap-2dong, Songpa-gu, Seoul 138-736, South Korea; [email protected] HM and JYY contributed equally. Received 7 April 2014 Revised 31 July 2014 Accepted 25 August 2014
To cite: Moon H, Yoon JY, Lim HT, et al. Br J Ophthalmol Published Online First: [ please include Day Month Year] doi:10.1136/bjophthalmol2014-305361
ABSTRACT Purpose To evaluate the thickness of the macular ganglion cell and inner plexiform layer (GCIPL) using spectral domain optical coherence tomography (SD OCT) in patients with brain lesions. Methods This case-control study included 58 healthy subjects and 98 patients with brain lesions confirmed by MRI. GCIPL and peripapillary retinal nerve fiber layer ( pRNFL) thicknesses were determined using the Cirrus SD OCT. Area under the receiver operating characteristic curve (AUC) values of pRNFL and GCIPL thickness were used to discriminate patients with brain lesions from normal controls. Results Average GCIPL thickness showed a good correlation with visual field mean deviation (r2=0.342, p
