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Original paper

GV20-based acupuncture for animal models of acute intracerebral haemorrhage: a preclinical systematic review and meta-analysis Hui-qin Li, Ji-huang Li, Ai-ju Liu, Mai-yun Ye, Guo-qing Zheng

▸ Additional material is published online only. To view please visit the journal online (http://dx.doi.org/10.1136/ acupmed-2014-010546). Department of Neurology, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou, China Correspondence to Professor Guo-qing Zheng, Center of Neurology, the Second Affiliated Hospital of Wenzhou Medical University, 109 Xueyuan West Road, Wenzhou 325027, China; [email protected]. Received 14 February 2014 Revised 11 September 2014 Accepted 20 September 2014 Published Online First 23 October 2014

To cite: Li H-qin, Li J-huang, Liu A-ju, et al. Acupunct Med 2014;32:495–502.

ABSTRACT Background Spontaneous intracerebral haemorrhage (ICH) is the most devastating subtype of stroke, but there is currently no evidence-based treatment strategy. Acupuncture is a well-known traditional Chinese therapy for stroke-induced disability, and GV20 is the commonly used acupuncture point. Objective To evaluate the efficacy of GV20based acupuncture in animal models of acute ICH. Methods Studies of GV20-based acupuncture in animal models of acute ICH were identified from six databases up to July 2013. Study quality for each included article was evaluated according to the CAMARADES 10-item checklist. Outcome measures were neurological deficit scores and brain water content. All the data were analysed using RevMan V.5.1 software. Results Nineteen studies were identified describing procedures involving 1628 animals. The quality score of the studies ranged from 3 to 6, with a mean of 4.6. The global estimate of the effect of GV20-based acupuncture was 0.19 (95% CI 0.13 to 0.25, p

GV20-based acupuncture for animal models of acute intracerebral haemorrhage: a preclinical systematic review and meta-analysis.

Spontaneous intracerebral haemorrhage (ICH) is the most devastating subtype of stroke, but there is currently no evidence-based treatment strategy. Ac...
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