American Journal of Transplantation 2015; 15: 535–540 Wiley Periodicals Inc.

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Copyright 2015 The American Society of Transplantation and the American Society of Transplant Surgeons doi: 10.1111/ajt.12987

Brief Communication

High Prevalence of Hepatitis B Nonimmunity in Vaccinated Pediatric Liver Transplant Recipients D. H. Leung1,2,*, M. Ton-That2, J. M. Economides1,2 and C. M. Healy1,3

Received 20 January 2014, revised 11 August 2014 and accepted for publication 12 August 2014

1

Department of Pediatrics, Baylor College of Medicine, Houston, TX 2 Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Texas Children’s Hospital, Houston, TX 3 Division of Pediatric Infectious Diseases, Texas Children’s Hospital, Houston, TX
Corresponding author: Daniel H. Leung, [email protected]

Durable protection from hepatitis B virus (HBV) and other vaccine-preventable diseases assumes great importance due to improved long-term patient and graft survival rates in pediatric liver transplantation. Vaccine immunogenicity data in transplanted children is limited. This was a cross-sectional, single-center, point-prevalence study evaluating HBV immunity in 160 pediatric liver transplant recipients. Patients with hepatitis B surface antibody levels