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Circ Arrhythm Electrophysiol. Author manuscript; available in PMC 2017 June 01. Published in final edited form as: Circ Arrhythm Electrophysiol. 2016 June ; 9(6): . doi:10.1161/CIRCEP.115.003841.
High-Resolution Mapping of Ventricular Scar: Comparison between Single and Multi-Electrode Catheters Cory M. Tschabrunn, CEPS1,2, Sebastien Roujol, PhD2, Nicole C. Dorman, BSc3, Reza Nezafat, PhD2, Mark E. Josephson, MD1,2, and Elad Anter, MD1,2 1Harvard-Thorndike
Electrophysiology Institute, Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA
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2Cardiovascular
Division, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA
3Biosense
Webster, Johnson & Johnson, Diamond Bar, CA
Abstract Background—Mapping resolution is influenced by electrode size and interelectrode spacing. The aims of this study were to establish normal electrogram criteria for 1mm multielectrodemapping catheters (Pentaray®) in the ventricle and to compare its mapping resolution within scar to standard 3.5mm catheters (Smart-Touch Thermocool®).
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Methods and Results—Three healthy swine and 11 swine with healed myocardial infarction underwent sequential mapping of the left ventricle with both catheters. Bipolar voltage amplitude in healthy tissue was similar between 3.5mm and 1mm multielectrode catheters with a 5th percentile of 1.61mV and 1.48mV, respectively. In swine with healed infarction, the total area of low bipolar voltage amplitude (defined as