Hindawi International Journal of Inflammation Volume 2017, Article ID 8608716, 7 pages https://doi.org/10.1155/2017/8608716
Research Article High Vitamin D Levels May Downregulate Inflammation in Patients with Behçet’s Disease Fahd Adeeb,1,2,3,4 Maria Usman Khan,1,2,3 Xia Li,2,5 Austin G. Stack,2,3,6 Joseph Devlin,1 and Alexander D. Fraser1,2,3 1
Department of Rheumatology, University Hospital Limerick, Limerick, Ireland Graduate Entry Medical School, University of Limerick, Limerick, Ireland 3 Health Research Institute, University of Limerick, Ireland 4 Department of Medicine, Universiti Teknologi MARA, Sungai Buloh, Selangor, Malaysia 5 Department of Mathematics and Statistics, La Trobe University, Melbourne, VIC, Australia 6 Department of Nephrology, University Hospital Limerick, Limerick, Ireland 2
Correspondence should be addressed to Fahd Adeeb; [email protected] Received 16 February 2017; Revised 1 May 2017; Accepted 9 May 2017; Published 4 June 2017 Academic Editor: Jian-Dong Li Copyright © 2017 Fahd Adeeb et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Vitamin D plays a significant role in the immune system modulation and may confer a protective role in autoimmune diseases. We conducted a case-control study to compare 25(OH)D levels in patients with BD who were managed at a regional rheumatology programme in the midwest region of Ireland compared to matched controls. Healthy controls were selected from the Irish health system and matched in 1 : 5 ratio for age, sex, and the month of the year. 25(OH)D levels
Research Article High Vitamin D Levels May Downregulate Inflammation in Patients with Behçet’s Disease Fahd Adeeb,1,2,3,4 Maria Usman Khan,1,2,3 Xia Li,2,5 Austin G. Stack,2,3,6 Joseph Devlin,1 and Alexander D. Fraser1,2,3 1
Department of Rheumatology, University Hospital Limerick, Limerick, Ireland Graduate Entry Medical School, University of Limerick, Limerick, Ireland 3 Health Research Institute, University of Limerick, Ireland 4 Department of Medicine, Universiti Teknologi MARA, Sungai Buloh, Selangor, Malaysia 5 Department of Mathematics and Statistics, La Trobe University, Melbourne, VIC, Australia 6 Department of Nephrology, University Hospital Limerick, Limerick, Ireland 2
Correspondence should be addressed to Fahd Adeeb; [email protected] Received 16 February 2017; Revised 1 May 2017; Accepted 9 May 2017; Published 4 June 2017 Academic Editor: Jian-Dong Li Copyright © 2017 Fahd Adeeb et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Vitamin D plays a significant role in the immune system modulation and may confer a protective role in autoimmune diseases. We conducted a case-control study to compare 25(OH)D levels in patients with BD who were managed at a regional rheumatology programme in the midwest region of Ireland compared to matched controls. Healthy controls were selected from the Irish health system and matched in 1 : 5 ratio for age, sex, and the month of the year. 25(OH)D levels
